
Getting to grips with the plant metabolic network
... genome.ad.jp/ [23]), though the only specific maps for higher plants are for Arabidopsis thaliana (thale cress) and Oryza sativa (rice)}, and searching for each enzyme in the database BRENDA {BRaunschweig ENzyme DAtabase (http://www.brenda.unikoeln.de/ [24])} for organism-specific literature. The go ...
... genome.ad.jp/ [23]), though the only specific maps for higher plants are for Arabidopsis thaliana (thale cress) and Oryza sativa (rice)}, and searching for each enzyme in the database BRENDA {BRaunschweig ENzyme DAtabase (http://www.brenda.unikoeln.de/ [24])} for organism-specific literature. The go ...
Tetrahymena Contain Two Distinct and Unusual High Mobility Group
... these HMG-like proteins in acid extracts from macronuclei isolated by the method of Gorovsky et al. (1975) suggested the possibility that LG-1 and LG-2 may be proteolytic breakdown products of histone H1 (see Gorovsky et al., 1974). Fig. 1, A and C, however, indicate that significant quantities of L ...
... these HMG-like proteins in acid extracts from macronuclei isolated by the method of Gorovsky et al. (1975) suggested the possibility that LG-1 and LG-2 may be proteolytic breakdown products of histone H1 (see Gorovsky et al., 1974). Fig. 1, A and C, however, indicate that significant quantities of L ...
design of lupin seeds lactic acid fermentation – changes of
... the use of legumes as a source of protein is somewhat limited because of low digestibility of most plant proteins. The digestibility of lupin protein could be improved by using lactic acid fermentation. The aim of this study was to evaluate the influence of solid state fermentation (SSF) with Lactob ...
... the use of legumes as a source of protein is somewhat limited because of low digestibility of most plant proteins. The digestibility of lupin protein could be improved by using lactic acid fermentation. The aim of this study was to evaluate the influence of solid state fermentation (SSF) with Lactob ...
PDF File
... the exocyclic amine group of G is proposed to be involved in an additional interaction with residue G264 (Figures 1, 2, and 3),[11] and the residual sevFigure 3. Testing the possible contact between the 2’-OH group of A261 and the exocyclic amine group of guanosine. a) Values of kcat/KM for the reac ...
... the exocyclic amine group of G is proposed to be involved in an additional interaction with residue G264 (Figures 1, 2, and 3),[11] and the residual sevFigure 3. Testing the possible contact between the 2’-OH group of A261 and the exocyclic amine group of guanosine. a) Values of kcat/KM for the reac ...
2006 Program
... “Production of the cold shock protein CspA by Staphylococcus aureus” Andrei Pomerantsev; Tallant-Blanco C.; Yeh, L; Gomis-Ruth, F.X.; Leppla, S.H. “Cre/Lox application to functional genomics of bacteria” Kimberly J. Mueller, Maurine D. Miner, Dr. Nancy E. Freitag “Novel mutations contributing to the ...
... “Production of the cold shock protein CspA by Staphylococcus aureus” Andrei Pomerantsev; Tallant-Blanco C.; Yeh, L; Gomis-Ruth, F.X.; Leppla, S.H. “Cre/Lox application to functional genomics of bacteria” Kimberly J. Mueller, Maurine D. Miner, Dr. Nancy E. Freitag “Novel mutations contributing to the ...
Identification and Analysis of Dicer Associated Proteins in
... We aimed to identify proteins interacting with human Dicer. Specific antiDicer antibodies were used to immunoprecipitate Dicer from HEK293 and HeLa cells and co-immunoprecipitating proteins were analyzed by mass spectrometry. Proteins identified to specifically co-purify with Dicer fall into differe ...
... We aimed to identify proteins interacting with human Dicer. Specific antiDicer antibodies were used to immunoprecipitate Dicer from HEK293 and HeLa cells and co-immunoprecipitating proteins were analyzed by mass spectrometry. Proteins identified to specifically co-purify with Dicer fall into differe ...
Tendency for Local Repetitiveness in Amino Acid Usages in Modern
... Systematic analyses of human proteins show that neural and immune system-speci®c, and therefore, relatively ``modern'' proteins have a tendency for repetitive use of amino acids at a local scale (1-20 residues), while ancient proteins (human homologues of Escherichia coli proteins) do not. Those pr ...
... Systematic analyses of human proteins show that neural and immune system-speci®c, and therefore, relatively ``modern'' proteins have a tendency for repetitive use of amino acids at a local scale (1-20 residues), while ancient proteins (human homologues of Escherichia coli proteins) do not. Those pr ...
Molecular Recognition of Amino Acids, Peptides, and Proteins by
... Molecular recognition is the process by which one molecule associates with another molecule via specific noncovalent interactions. The specificity of these interactions allows molecules to assemble in manner that is predetermined by their structural attributes, including size, shape, and polarity. I ...
... Molecular recognition is the process by which one molecule associates with another molecule via specific noncovalent interactions. The specificity of these interactions allows molecules to assemble in manner that is predetermined by their structural attributes, including size, shape, and polarity. I ...
Plasmodium falciparum enolase - Tata Institute of Fundamental
... showing quite promising behavior as detection tools, drug targets and vaccine candidates [5–8]. P. falciparum enolase (Pfen) (EC 4.2.1.11), the dehydrating glycolytic metalloenzyme that catalyzes the inter conversion of 2-phosphoglyceric acid (2-PGA) and phosphoenolpyruvate (PEP), has not yet been c ...
... showing quite promising behavior as detection tools, drug targets and vaccine candidates [5–8]. P. falciparum enolase (Pfen) (EC 4.2.1.11), the dehydrating glycolytic metalloenzyme that catalyzes the inter conversion of 2-phosphoglyceric acid (2-PGA) and phosphoenolpyruvate (PEP), has not yet been c ...
pH-induced conformational changes in human ABO(H) blood group
... Glycosyltransferases are a diverse group of enzymes (Paulson and Colley 1989; Sinnott 1990; Campbell et al. 1997; Charnock and Davies 1999; Unligil and Rini 2000; Bourne and Henrissat 2001; Breton et al. 2001; Coutinho et al. 2003; Qasba et al. 2005; Breton et al. 2006; Thiyagarajan et al. 2012) tha ...
... Glycosyltransferases are a diverse group of enzymes (Paulson and Colley 1989; Sinnott 1990; Campbell et al. 1997; Charnock and Davies 1999; Unligil and Rini 2000; Bourne and Henrissat 2001; Breton et al. 2001; Coutinho et al. 2003; Qasba et al. 2005; Breton et al. 2006; Thiyagarajan et al. 2012) tha ...
The phosphopantetheinyl transferases
... Vagelos and Elovson.3 Since then, many other PPTases have been discovered to play the same role in a wide variety of secondary metabolic pathways.1,4 Many of these PPTases have been described on the gene and protein levels providing for intense biochemical characterization. With the mapping of their ...
... Vagelos and Elovson.3 Since then, many other PPTases have been discovered to play the same role in a wide variety of secondary metabolic pathways.1,4 Many of these PPTases have been described on the gene and protein levels providing for intense biochemical characterization. With the mapping of their ...
Distinct C-terminal Amino Acid Sequence Motifs Serve
... Tail-anchored (TA) proteins are a unique class of functionally diverse membrane proteins that are defined by their single C-terminal transmembrane domain and their ability to insert post-translationally into specific organelles in an Ncytosol-CIMS orientation. While in recent years considerable prog ...
... Tail-anchored (TA) proteins are a unique class of functionally diverse membrane proteins that are defined by their single C-terminal transmembrane domain and their ability to insert post-translationally into specific organelles in an Ncytosol-CIMS orientation. While in recent years considerable prog ...
University: Suez Canal University Faculty of Medicine Course
... Knowledge and Understanding: By the end of the course the student should be able to: A1 Life, Water& Acid Base Balance: 1. Explain the structure of an atom, molecules and define isotopes and show how they are used for diagnosis of diseases . 2. Recognize the essential elements required for life. 2. ...
... Knowledge and Understanding: By the end of the course the student should be able to: A1 Life, Water& Acid Base Balance: 1. Explain the structure of an atom, molecules and define isotopes and show how they are used for diagnosis of diseases . 2. Recognize the essential elements required for life. 2. ...
POLYPEPTIDE SEQUENCING
... The two techniques most commonly used are I.E.F. followed by SDSPAG electrophoresis. Analysis of proteins is performed using MALDI - a new(-ish) mass spectrometry ionisation technique which uses lasers (Matrix Assisted ...
... The two techniques most commonly used are I.E.F. followed by SDSPAG electrophoresis. Analysis of proteins is performed using MALDI - a new(-ish) mass spectrometry ionisation technique which uses lasers (Matrix Assisted ...
Purified Hexameric Epstein-Barr Virus-Encoded BARF1 Protein for Measuring Anti-BARF1 Antibody
... (37). Unfortunately, the study does not agree with the more recent knowledge of rapid and complete secretion of BARF1. Aberrant EBV serology is commonly used to support NPC diagnosis and provides an affordable approach for population screening (8, 26). Antibodies targeting the BARF1 protein could be ...
... (37). Unfortunately, the study does not agree with the more recent knowledge of rapid and complete secretion of BARF1. Aberrant EBV serology is commonly used to support NPC diagnosis and provides an affordable approach for population screening (8, 26). Antibodies targeting the BARF1 protein could be ...
αII-Spectrin interacts with Tes and EVL, two actin
... the erythrocyte plasma membrane, is considered as an essential scaffold underlying different lipid bilayers in all animal cells [1]. Spectrins are giant extended flexible molecules composed of two subunits (α and β), which intertwine to form αβ-heterodimers, a pair of αβ-heterodimers forms the spect ...
... the erythrocyte plasma membrane, is considered as an essential scaffold underlying different lipid bilayers in all animal cells [1]. Spectrins are giant extended flexible molecules composed of two subunits (α and β), which intertwine to form αβ-heterodimers, a pair of αβ-heterodimers forms the spect ...
Structure and function of the eukaryotic ADP
... ADPGKs are known, no structure of a eukaryotic ADPGK had been solved before the work undertaken in this thesis. In this thesis, the kinetic analysis of a recombinant form of Homo sapiens ADPGK and the crystal structure of a truncated form of Mus musculus ADPGK are presented. Both enzymes were expres ...
... ADPGKs are known, no structure of a eukaryotic ADPGK had been solved before the work undertaken in this thesis. In this thesis, the kinetic analysis of a recombinant form of Homo sapiens ADPGK and the crystal structure of a truncated form of Mus musculus ADPGK are presented. Both enzymes were expres ...
promoting training adaptations through nutritional
... AMPK is a critical signalling protein involved in the regulation of multiple metabolic and growth responses in skeletal muscle in response to exercise. This ‘fuel sensing’ enzyme is involved in acute exercise-induced events and also plays an obligatory role in adapting skeletal muscles to repeated b ...
... AMPK is a critical signalling protein involved in the regulation of multiple metabolic and growth responses in skeletal muscle in response to exercise. This ‘fuel sensing’ enzyme is involved in acute exercise-induced events and also plays an obligatory role in adapting skeletal muscles to repeated b ...
PCNA Protein Expression during Spermatogenesis of the
... PCNA are derived from different mRNAs produced by alternative splicing processes. The two proteins were equally recognized by antibodies raised against different epitopes, and were identical in the N-terminal amino acid sequence. Anti-phosphoamino acid antibodies recognized the 36-kDa form of PCNA b ...
... PCNA are derived from different mRNAs produced by alternative splicing processes. The two proteins were equally recognized by antibodies raised against different epitopes, and were identical in the N-terminal amino acid sequence. Anti-phosphoamino acid antibodies recognized the 36-kDa form of PCNA b ...
Globins in Nonvertebrate Species: Dispersal by Horizontal Gene
... John Czeluzniak, 5 Morris Goodman, 5 Mark Blaxter,ll and Serge Vinogradofl *Department of Biochemistry, University of Antwerp; TDepartment of Morphology, Systematics and Ecology, University of Ghent; *Department of Radiology and Enrico Fermi Institute, University of Chicago; SDepartment of Anatomy, ...
... John Czeluzniak, 5 Morris Goodman, 5 Mark Blaxter,ll and Serge Vinogradofl *Department of Biochemistry, University of Antwerp; TDepartment of Morphology, Systematics and Ecology, University of Ghent; *Department of Radiology and Enrico Fermi Institute, University of Chicago; SDepartment of Anatomy, ...
Interactome

In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.