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Cells Structure and Function What We Will Learn • How were cells discovered? • What are the basic differences between types of cells? • How are cells structured? • What are the functions of different cell structures – how do they work? Cellular Basis of Life • Cell – Smallest living unit of any organism – Capable of carrying out all life functions • Uni-cellular life – single cell • Multi-cellular life – many cells with different functions History of Cell Discovery • Most cells too small to see with naked eye • Invention of microscope enabled scientists to discover and study cells Scientists and Cell Study Leewenhoek: – Simple microscope – Observed organisms in pond water, blood cells, bacteria Hooke: – Crude compound microscope – Observed cell walls of cork – Coined term “cells” Schleiden: (Botanist) – Stated all plants are made of cells Schwann: (Zoologist) – Stated all animals made of cells Virchow: – Stated all cells come from pre-existing cells Brown: – First to identify an internal cell structure (nucleus) From this research and observation of living things a scientific theory was developed (took over 200 years!) Cell Theory 1. All living things made up of cells 2. Cells are the basic units of structure and function in living things 2. New cells come from existing cells Exceptions to Cell Theory Viruses: – Need host cell to carry out life processes Exceptions to Cell Theory Mitochondria & Chloroplasts: – Organelles that reproduce inside cell – Have own unique genetic material – Can’t survive outside of cell Exceptions to Cell Theory The First Cell • Where did it come from? • What was it like? 2 Basic Types of Cells • Prokaryotes • Eukaryotes Both Types: – Contain DNA – Are surrounded by cell (plasma) membrane – Carry out all life functions Prokaryotes – No nucleus – Lack internal membrane bound organelles – DNA in cytoplasm – Metabolic functions take place in cytoplasm – Smaller, simpler more primitive cells • Ex: bacteria Eukaryotes – Nucleus encloses DNA – Specialized membrane bound organelles (more compartmentalized) – Larger, more complex • Ex: protists, plants, animals, fungi Cell Structure and Organelles The Cell as a Factory • Each organelle carries out a specialized function. • Ex: – Oversee cell activities – Provide energy – Produce products – Get rid of wastes Cell as Factory Cell Membrane • Also called “plasma membrane” • Separates inside of cell from outside environment • Made of lipid and protein bi-layer • Called the “fluid mosaic model” • Controls substances going in and out of cell (selectively permeable) http://youtu.be/Rl5EmUQdkuI Channel Proteins: allow for selective movement of materials in and out of cell membrane Phospholipids: molecules that line up in a bi-layer (two layers) to make cell membrane Hydrophilic = “water loving” end Hydrophobic = “water fearing” end Cell Wall • Found in plants, fungi, some bacteria and protists • NOT in animal cells • Inflexible structure • Made of cellulose fibers woven together – In fungi made of chitin • Protect cell and give it support and shape Liquid, gel-like substance inside cell membrane (75% water) Many substances dissolved in it Most chemical reactions take place here. Cytoplasm “Cyclosis”: the movement of materials through cytoplasm http://youtu.be/7jw-N82tHjc Cytoskeleton • Internal framework inside cytoplasm • Made of fibrous rods – microfilaments – microtubules • Maintains cell shape • Supports and moves organelles Images of Cytoskeleton Nucleus • Directs cell activities • Eukaryotic Cells ONLY!! • Control center for metabolic functions and reproduction • Provides instructions for making proteins and other molecules for the cell Structure of the Nucleus Nuclear envelope: membrane surrounding nucleus Nuclear pores: allow materials to leave or enter Nucleolus: dark inner area. Ribosomes formed here Chromatin: • coiled DNA, in the nucleus • contains instructions for building proteins • unwound and spread out • Communicates with rest of cell by movement of molecules through nuclear pores • During cell division, chromatin condenses to form chromosomes that replicate and divide Endoplasmic Reticulum (E.R.) • Channels to move materials inside cell • Highly folded (increases surface area) Rough ER: “bumpy” with ribosomes attached to surface Smooth ER: doesn’t have ribosomes on surface Ribosomes • Site of protein synthesis • Small round structures • Cell has a lot of them (needs proteins!) • May be free floating in cytoplasm or attached to the “rough” E.R. Golgi Bodies • Stack of membranes (like pancakes) • Involved in modifying, packaging, storing and releasing products Vesicles: packages containing proteins that are pinched off to be used inside cell or transported out. Lysosomes • Membrane enclosed vesicles • Hydrolytic digestive enzymes • Breaks down food and worn out cell parts • Formed by Golgi Bodies http://youtu.be/ekdIEpSf-1I Vacuoles • Stores water, food, wastes • Much larger in plant cells – Used to help give cell shape, structure • Food Vacuoles: merge with lysosomes to digest food Contractile Vacuoles: – Found in single celled freshwater organisms like paramecium – “contract” to pump out excess water from cell Energy and the Cell Mitochondria • Powerhouse of the cell • Site of cellular respiration • Makes usable energy (ATP) • Simple sugars are broken down to release energy as ATP • The more energy a cell needs the more mitochondria it has! Cristae: Highly folded inner membrane that allows for increased surface area for cellular respiration reactions Chloroplasts • FOUND IN PLANT CELLS ONLY!! • Site of photosynthesis Light energy is transformed to chemical energy in the form of sugar • Chlorophyll: (green pigment) that captures sunlight • Grana: Inner membranes in “coin” stacks containing chlorophyll • Stroma: enzyme filled fluid surrounding grana Endosymbiotic Theory • Mitochondria and chloroplasts have own DNA and can reproduce on their own. • Perhaps they were a primitive type of prokayotic cell that became incorporated into another • Symbiotic relationship = both cells benefit Evolution of Complex Life http://youtu.be/q71DWYJD-dI Centrioles • FOUND IN ANIMAL CELLS ONLY!! • Pair of small cylindrical organelles found near nucleus • Function in cell division to pull chromosomes apart Cell Movement • Cilia: short hair like projections used for locomotion • Flagella: long whip-like tail used for locomotion • http://youtu.be/QGAm6hMysTA • • • • Pseudopods: “false foot” Projections of the cell membrane Used for locomotion Used to surround and engulf food Limitations of Cell Size • Size is limited by the cell’s need to intake nutrients and excrete wastes • Smaller the cell is, the closer all parts are to the external environment. • Surface area to volume ratio • http://www.youtube.com/watch?v=rnNAcLJNc3s&feature =share&list=ULrnNAcLJNc3s • http://youtu.be/LP7xAr2FDFU • • • • • • Passive transport http://youtu.be/JShwXBWGMyY Osmosis http://youtu.be/XclGRjnilsk Membrane http://youtu.be/GW0lqf4Fqpg Cellular Organization • In multicelluar organisms cells are just the start of how things are organized. – Cells – Tissues: groups of cells that function together to perform an activity – Organs: groups of tissues performing one main function – Organ Systems: organs working together – Organism