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Spinal Cord and Nerves The Nervous System  Coordinates the activity of muscles, organs, senses, and actions  Made up of nervous tissue  Has 3 main functions:    1. Receives sensory Input 2. Integration 3. Dictates motor output Divisions of the Nervous System  Central Nervous System (CNS)  Brain and spinal cord  Interprets incoming sensory signals  Dictates motor responses  Peripheral Nervous System (PNS)  Ganglia  Nerves  Cranial nerves and spinal nerves  Communication between regions of body and CNS Review of Nervous Cells  Neuron  Cell body  Dendrite  Axon  Myelin Sheath  Neuroglia  Interneuron  Reflex Arc  Synapse Organization of a Nerve  Endoneurium  Surrounds each axon (nerve fiber)  Myelinated and Unmyelinated axons  Motor and Sensory nerve fibers  Loose CT  Perineurium  Bundles axons into fascicles  CT  Epineurium  Bundles fascicles into a nerve  Fibrous CT  CT layers contain blood vessels Types of Nerve Signals/Fibers  Sensory (afferent)   Picked up by sensory receptors thru body Carried by nerve fibers of PNS into CNS  Motor (efferent)    Carried away from the CNS by nerve fibers into PNS Innervate muscles and glands Causes these organs to contract or secrete  Remember: SAME Sensory and Motor Signals/Fibers  Somatic sensory Body senses  touch, pressure, temperature, vibration of body, muscles stretching, balance  Visceral sensory  Organ senses  Stretch, pain, temperature in organs  (eg) nausea, hunger, cramps  Somatic motor  Body movement  Voluntary contraction of skeletal muscles  Visceral motor  Organ movement  Contraction of smooth muscle, glands  = Autonomic Nervous System (involuntary)  CNS – Spinal Cord  Runs through vertebral canal of the vertebral     column Protected by bone, meninges, and cerebrospinal fluid Spinal cord made of a core of gray matter surrounded by white matter 31 pairs of spinal nerves branch off spinal cord through intervertebral foramen Functions in many ways:    Involved in sensory and motor innervation of body inferior to the head (through spinal nerves) Provides a 2-way conduction pathway for signals between body and brain Major center for reflexes Gross Structure of Inferior End of Spinal Cord Spinal Cord Segments Meninges of Spinal Cord  Dura mater (superficial) Spinal dural sheath  Does not attach to bone  Epidural space  Fat and veins  Between dura mater and vertebra  Subdural space   Between dura mater and arachnoid Meninges of Spinal Cord  Arachnoid mater (middle) Impermeable layer = barrier  Raised off pia mater by rootlets  Subarachnoid space  Between arachnoid and pia mater  Contains CSF  Pia mater (deep)  Highly vascular  Adheres to brain/spinal cord tissue  Regions of Spinal Cord  Cervical  Thoracic  Lumbar  Sacral  Coccygeal  Cervical + Lumbar enlargements  Cauda equina  Conus medullaris  Filum terminale Gray Mater  Consists of neuron cell bodies, unmyelinated axons, dendrites, and neuroglia  Shaped like an “H”   Gray commissure (crossbar) Central canal  Posterior horns  Anterior horns Gray Mater  Posterior horns   Consist of interneurons that transmit in from outside spinal cord into it Dorsal root contain sensory fibers   Somatic Sensory (SS) Visceral Sensory (VS) Dorsal root ganglia - swelling in dorsal root that these interneurons pass through  Anterior horns  Cell bodies of motor neurons send info out of spinal cord to muscles and glands  Ventral Root contains Motor Fibers    Visceral Motor Somatic Motor White Mater  Surrounds gray matter  Composed of myelinated and unmyelinated axons  Divided into white columns (funiculi)    Posterior funiculus Anterior funiculus Lateral funiculus  Allow for communication between   Parts of the spinal cord Spinal cord and brain White Mater  3 types of nerve fibers:  Ascending    Descending     Carry sensory info from sensory neurons of body to brain touch, pressure, pain, temperature Carry motor instructions from brain to spinal cord Contraction of muscles and secretion of glands control precise, skilled movement = writing, maintain balance, create movement Commissural  Cross from one side of cord to the other Spinal Nerves (31 Pairs)  Part of the PNS (Somatic)  Lie in intervertebral foramina Send lateral branches to body  Named according to their point of issue from the vertebral column  8 pairs of cervical spinal nerves; C1-C8  12 pairs of thoracic spinal nerves; T1-T12  5 pairs of lumbar spinal nerves; L1-L5  5 pairs of sacral spinal nerves; S1-S5  1 pair of coccygeal spinal nerves; C01  Spinal Nerves  Each spinal nerve connected to spinal cord via dorsal (sensory) and ventral (motor) root  Spinal nerves branch into dorsal ramus and ventral ramus   Ventral ramus  Connects to rami communicates, which then lead to sympathetic chain ganglia  Supply anterior and lateral regions of the neck, trunk, and limbs Dorsal ramus  Supply the dorsum of the neck and trunk (back) The Big Picture  Just lateral to intervertebral foramen, each spinal nerve then splits in 2   Dorsal Rami Ventral Rami  Contain BOTH Sensory and Motor fibers!! Put It All Together! Autonomic Nervous System = Visceral Motor Autonomic Nervous System  Visceral Motor Function  Not easily controlled by will  Get nervous and sweat  Innervate smooth muscle, cardiac muscle, glands  Regulate visceral function  Heart rate, blood pressure, digestion, urination  Has 2 divisions:  Parasympathetic  Sympathetic ANS  Parasympathetic  Enables body to unwind and calm down  Most active when body at rest  Routine maintenance functions  Craniosacral division  Fibers emerge from brain and sacral spinal cord  Sympathetic  “fight or flight”  Mobilizes the body during extreme situations  Becomes active when extra metabolic effort needed  Thoracolumbar division  Fibers arise from thoracic and lumbar parts of spinal cord Autonomic Division of PNS Parasympathetic Innervation Somatic Nervous System  Innervates skeletal muscle  Neurons runs from CNS directly to muscle  Consists of single neuron plus skeletal muscle cells  Voluntary control  Running, moving limbs, typing on a computer! Nervous System Overview
 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                            