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FOXP2 -The “Language Gene“Presentation by Melanie Selle & Hüseyin Balim Outline • Introduction • Discovery – – KE-family Pedigree of the KE family • Description of F0XP2 • Function • FOXP2 in humanbeings – • FOXP2 in animals – • Developmental dyspraxia Songbirds Evolution Aspect and Scientific Background – – – Scientists find gene 'switch' linked to speech The importance of being human * Mice Given 'Human' Version of Speech Gene* • Conclusion • References Central Questions Why can just a single gene have such a huge impact on our language ability? What really differs animal from human communication? Discovery • 1990 discovered by Myrna Gopnik • During research on the KE family KE family • Affected family members exhibit specific language impairment • Disorder is associated with a mutation in a single autosomal-dominant gene Pedigree of the KE family Where is the FOXP2 gene located? • Correlation of sets of small stretches of DNA between affected and notaffected members of the KE family Variations in the small locus of the long arm of chromosome 7