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Transcript
Activated T cells
In this video we can see a T cell that becomes activate
when interacts with a dendritic cell.
The T cell is label with a dye, the fluorescent when it binds
calcium ions at the moment the T cell is not activated, its
intracellular calcium concentrations are low and so little
green fluorescent is visible as the T cell contacts the surface
of the dendritic cell.
We can see suddenly fluorescent bright green as it
becomes activated. How ever is thus continue to move
crolling over the surface of the DCs, perhaps to sample the
cell display a peptide MHC complexes, eventually the T
cell loses interest while is still contact in the DC we can see
the fluorescent start to fade, the T cell then migrates away
from the dendritic cell.