* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Demonstrate skill in organic chemistry techniques.
Survey
Document related concepts
Cracking (chemistry) wikipedia , lookup
Discodermolide wikipedia , lookup
Bottromycin wikipedia , lookup
Marcus theory wikipedia , lookup
Strychnine total synthesis wikipedia , lookup
Elias James Corey wikipedia , lookup
Enantioselective synthesis wikipedia , lookup
George S. Hammond wikipedia , lookup
Hydroformylation wikipedia , lookup
Diels–Alder reaction wikipedia , lookup
Ring-closing metathesis wikipedia , lookup
Asymmetric induction wikipedia , lookup
Stille reaction wikipedia , lookup
Ene reaction wikipedia , lookup
Petasis reaction wikipedia , lookup
Wolff rearrangement wikipedia , lookup
Transcript
South Central College Organic Chemistry I Course Outcome Summary Course Information Description Organic Chemistry I is the first course in a two semester sequence which covers the structure, stereochemistry, physical properties, reactivity, reaction mechanisms and synthesis of carbon-containing compounds. Emphasis on alkanes, alkenes, alkynes, alcohols, alkyl halides, aldehydes, ketones, and carboxylic acids and their derivatives. Laboratory experiments will integrate green methods into common synthetic techniques and the preparation and reactions of functional groups. Instructional Level Associate Degree Total Credits 5.00 Total Hours 96.00 Types of Instruction Instruction Type Credits Lecture 4 Lab 1 Pre/Corequisites Prerequisite Chem 121 Course Competencies 1 Demonstrate understanding of the structure and properties of organic molecules. Learning Objectives Use valence bond theory and molecular orbital theory to describe covalent bonding. Draw resonance structures, identify isomers, and explain the difference between them. Predict general trends in physical properties. Identify the general classes of organic compounds. 2 Describe the structure and stereochemistry of alkanes. Learning Objectives Draw and name isomers of alkanes and cycloalkanes, draw alkane conformations. Draw alkane and cycloalkane conformations, compare their energies, and predict the most stable conformations. 3 Demonstrate understanding of organic reactions through the study of mechanisms, thermodynamics, and kinetics. Course Outcome Summary - Page 1 of 4 Thursday, September 13, 2012 2:10 PM Learning Objectives Propose mechanisms for reactions. Draw reaction-energy diagrams. Use the mechanism, thermodynamics, and kinetics of a reaction to predict which of several possible products is the major product. Identify reactive intermediates and explain their properties. 4 Compare and differentiate stereoisomers using an understanding of their three-dimensional structures. Learning Objectives Recognize structures that have stereoisomers, chiral structures, and asymmetric carbon atoms, and identify the relationships between stereoisomers. Explain the relationships between optical activity and chirality, optical purity, and enantiomeric excess. 5 Demonstrate understanding of the properties and reactions of alkyl halides. Learning Objectives Name alkyl halides and explain their physical properties and common uses. Predict the products of substitution and elimination reactions and explain what factors favor each type of reaction. Predict which mechanisms and products are most likely for a given set of reaction conditions. 6 Describe the properties of alkenes and show how they can be synthesized. Learning Objectives Draw and name alkenes and cycloalkenes, and calculate the number of double bonds and rings from a molecular formula. Use the structure of alkenes to explain their stability. Demonstrate the synthesis of alkenes by eliminations from alkyl halides and alcohols. 7 Predict reactions of alkenes. Learning Objectives Demonstrate understanding of electrophilic additions. Predict products of reactions of alkenes, including regiochemistry and stereochemistry. Explain observed products of alkene reactions using a mechanistic approach. Solve multistep synthesis problems. 8 Demonstrate understanding of the properties and reactions of alkynes. Learning Objectives Draw and name alkynes, cycloalkynes, and their derivatives. Show how alkynes are synthesized by eliminations, additions, and substitutions. Predict products of the reactions of alkynes and propose mechanisms to explain observed products. Solve multistep synthesis problems. 9 Discuss the physical properties of alcohols and summarize the methods used to synthesize them. Learning Objectives Draw structures and name alcohols, phenols, diols, and thiols. Predict relative boiling points, acidities, and solubilities. Show the conversion of alcohols from alkenes, alkyl halides, and cabonyl compounds. Discuss the use of greener methods for the synthesis reactions using Grignard and organolithium reagents. 10 Summarize the types of reactions that alcohols undergo and the reagents that used in these reactions. Course Outcome Summary - Page 2 of 4 Thursday, September 13, 2012 2:10 PM Learning Objectives Identify oxidized and reduced species in an oxidation-reduction reaction. Predict products of reactions of alcohols with various agents. Propose mechanisms to explain alcohol reactions. Plan multistep syntheses. 11 Identify and explain the formation and reactions of ethers, epoxides, and thioethers. Learning Objectives Draw and name ethers and heterocyclic ethers. Explain trends in their physical properties. Predict products and propose mechanisms for the reactions of ethers and epoxides. Explain why sulfides are more reactive than ethers. 12 Discuss the properties and reactions of ketones and aldehydes. Learning Objectives Draw and name ketones and aldehydes. Propose syntheses of ketones and aldehydes from compounds containing other functional groups, and propose syntheses using ketones and aldehydes as starting materials and intermediates. Predict products and propose mechanisms for the reactions of ketones and aldehydes. 13 Analyze the structure, properties, and reactions of amines, including their importance as biological compounds. Learning Objectives Draw and name amines and explain the variation in their basicity. Predict products and propose mechanisms for the reactions of amines and propose syntheses of amines from compounds containing other functional groups. 14 Analyze and examine the structure, properties, and reactions of carboxylic acids. Learning Objectives Draw and name carboxylic acids and dicarboxylic acids; describe trends in acidity and physical properties and explain variations in their acidity. Predict products and propose mechanisms for reactions of carboxylic acids. Propose syntheses of carboxylic acids from compounds containing other functional groups and propose syntheses using carboxylic acids and chlorides as starting materials and intermediates. 15 Show understanding of the properties and reactions of carboxylic acid derivatives. Learning Objectives Draw and name carboxylic acid derivatives, describe trends in their properties and compare reactivities. Predict products and propose mechanisms for the reactions of carboxylic acid derivatives. Propose syntheses of acid derivatives from compounds containing other functional groups and propose syntheses using acid derivatives as starting materials and intermediates. 16 Analyze chemical reactions or processes to determine greenness. Learning Objectives Compare methods using parameters such as relative chemical hazards of reagents, environmental impact of materials and waste, transportation hazards, difficulty of synthetic method, and reaction efficiency. Perform an economic analysis of an experiment to demonstrate the economic vs. chemical issues involved in green chemistry. Recognize impact of solvent choice on reaction rate through experimentation of the kinetics of hydrolysis of tertButyl Chloride (exp 10) Monitor waste generated in a chemical reaction or process. Use computational methods in a molecular modeling program to explore design of safer products and synthetic efficiency (exp 11) Course Outcome Summary - Page 3 of 4 Thursday, September 13, 2012 2:10 PM Explore the use of alternative reaction media and reuse of reagents through synthesis and recrystallization of adipic acid. (exp 5) Demonstrate understanding of the use of mild reagents thorough the Glaser-Eglinton-Hay coupling. (exp 6) Compare methods of the preparation of stilbene dibromide. (exp 2, 3) Explore the use of water as a solvent through a palladium-catalyzed alkyne coupling. (exp 13) Calculate atom economy through experimentation of the diels-alder reaction in water. (exp) Demonstrate understanding of renewable feedstocks and design for degradation through experimentation of biodiesel syntheses. (exp) 17 Demonstrate skill in organic chemistry techniques. Learning Objectives Determine melting points of solids and liquids and demonstrate recrystallization through experimentation with an aldol condensation reaction. (exp 1) Perform a fractional distillation through the preparation and distillation of cyclohexene. (exp 4) Extract d-limonene from orange peel using liquid carbon dioxide. (exp) SCC Accessibility Statement If you have a disability and need accommodations to participate in the course activities, please contact your instructor as soon as possible. This information will be made available in an alternative format, such as Braille, large print, or cassette tape, upon request. If you wish to contact the college ADA Coordinator, call that office at 507-389-7222. Disabilities page http://southcentral.edu/academic-policies/disability-rights.html Course Outcome Summary - Page 4 of 4 Thursday, September 13, 2012 2:10 PM