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1 CELLS AND THEIR COMPONENTS. Embryonic stem cells Proudly made by Jose Antonio Luna 1 What is the basic unit of life? How are prokaryotic cells different from eukaryote cells? Where does photosynthesis and cellular respiration take place? What are chromosomes made of? Explain to your partner 3m.Proudly made by Jose Antonio Luna 2 1. THE CHEMICAL COMPONENTS OF CELLS. All living things are made of bioelements and biomolecules. Biomolecules are made of combinations of bioelements and can be inorganic such as water and mineral salts, and organic biomolecules such as carbohydrates, lipids, proteins and nucleic acids. Proudly made by Jose Antonio Luna 3 1. THE CHEMICAL COMPONENTS OF CELLS. WATER. Water is the most abundant molecule in living things because of its physical and chemical properties, such as its ability to dissolve substances. Proudly made by Jose Antonio Luna 4 1. THE CHEMICAL COMPONENTS OF CELLS. MINERAL SALTS. They are insoluble in water and are useful for forming skeletal structures. This is true for tricalcium phospate, found in bones, and calcium carbonate, present in the shells of molluscs. Proudly made by Jose Antonio Luna 5 1. THE CHEMICAL COMPONENTS OF CELLS. CARBOHYDRATES. They are organic biomolecules composed of carbon, hydrogen and oxygen molecules. There are different types: •Monosaccharides. They are the simplest carbohydrates. Some, such as glucose or fructose, provide energy for cells, while others, such as ribose , form part of nucleic acids. Proudly made by Jose Antonio Luna 6 1. THE CHEMICAL COMPONENTS OF CELLS. CARBOHYDRATES. •Disaccharides are formed by the union of two monosaccharide molecules (Sucrose, lactose and maltose). Proudly made by Jose Antonio Luna 7 1. THE CHEMICAL COMPONENTS OF CELLS. CARBOHYDRATES. •Polysaccharides consist of thousands of linked monosaccharide molecules. They store energy (starch) and provide structural support (cellulose). Proudly made by Jose Antonio Luna 8 1. THE CHEMICAL COMPONENTS OF CELLS. LIPIDS. Lipids are organic biomolecules that are insoluble in water. They are composed of carbon, hydrogen and oxygen. Types: TRIGLYCERIDES, which are formed by a molecule of glycerol and three fatty acids, and store large amounts of energy for cells. Proudly made by Jose Antonio Luna 9 1. THE CHEMICAL COMPONENTS OF CELLS. LIPIDS. WAXES, which are water-repellent and help control evaporation and hydration in both plants and animals. Proudly made by Jose Antonio Luna 10 1. THE CHEMICAL COMPONENTS OF CELLS. LIPIDS. PHOSPHOLIPIDS, which contain phosphoric acid. They make up part of cell membranes. Proudly made by Jose Antonio Luna 11 1. THE CHEMICAL COMPONENTS OF CELLS. LIPIDS. STEROIDS, which are an important group of lipids include cholesterol, vitamin D and male and female sex hormones. Proudly made by Jose Antonio Luna 12 ACTIVITIES. act 1, page 5. Proudly made by Jose Antonio Luna 13 2. PROTEIN AND NUCLEIC ACIDS. PROTEINS. Proteins are a large biomolecules that are made up of different combinations of 20 molecules called amino acids. Structure: The PRIMARY STRUCTURE of proteins is the linear sequence of amino acids in a single protein molecule. Proudly made by Jose Antonio Luna 14 2. PROTEIN AND NUCLEIC ACIDS. PROTEINS. Structure: The SECONDARY STRUCTURE refers to the folding of a protein into regular sub-structures. Proudly made by Jose Antonio Luna 15 2. PROTEIN AND NUCLEIC ACIDS. PROTEINS. Structure: The TERTIARY STRUCTURE refers to the three-dimensional arrangement and interaction of all the secondary structures to one another. Proudly made by Jose Antonio Luna 16 2. PROTEIN AND NUCLEIC ACIDS. PROTEINS. Structure: The QUATERNARY STRUCTURE. It is characteristic of large proteins, such as blood haemoglobin, Proudly made by Jose Antonio Luna 17 2. PROTEIN AND NUCLEIC ACIDS. PROTEINS. FUNCTIONS: Proteins perform many vital roles in the human body, including: Proudly made by Jose Antonio Luna 18 2. PROTEIN AND NUCLEIC ACIDS. NUCLEIC ACIDS. They are large, organic biomolecules, which are formed by the bonding of smaller molecules called nucleotides. Each nucleotide consists of three parts: a monosaccharide molecule (deoxyribose or ribose) a nitrogenous base (Adenine, guanine, thymine cytosine or uracil) and a phosphoric molecule. Proudly made by Jose Antonio Luna 19 2. PROTEIN AND NUCLEIC ACIDS. DNA. It is a molecule that carries genetic information. This information is stored in the genes, which are the functional units of DNA. Proudly made by Jose Antonio Luna 20 2. PROTEIN AND NUCLEIC ACIDS. DNA. A DNA molecule has the following characteristics: 1) Its nucleotides are composed of deoxyribose, phophoric acid and one of the following bases: adenine, guanine, cytosine or thymine. It does not contain ribose or uracil. 2) It has 2 strands of nucleotides, which are complementary because the base pairs are always opposite each other. 3) Double helix. Proudly made by Jose Antonio Luna 21 2. PROTEIN AND NUCLEIC ACIDS. DNA. A DNA molecule has the following characteristics: Proudly made by Jose Antonio Luna 22 2. PROTEIN AND NUCLEIC ACIDS. Proudly made by Jose Antonio Luna 23 3. THE STRUCTURE OF PROKARYOTIC AND EUKARYOTIC. PROKARYOTIC CELLS They are smaller and less complex. Bacteria, cyanobacteria and archaea are prokaryotes. The most important characteristics of prokaryotic cells are the following: 1) They don´t have a nucleus, consequently their genetic material is free in the cytoplasm. They can also have plasmids, which are small DNA fragments. Proudly made by Jose Antonio Luna 24 3. THE STRUCTURE OF PROKARYOTIC AND EUKARYOTIC. PROKARYOTIC CELLS: 2) They have a cell membrane. They can have other types of membranes such as cell wall and capsule. Proudly made by Jose Antonio Luna 25 3. THE STRUCTURE OF PROKARYOTIC AND EUKARYOTIC. PROKARYOTIC CELLS: 3) They have ribosomes, where proteins are produced, located in the cytoplasm 4) Many bacteria have pili and flagella. Proudly made by Jose Antonio Luna 26 3. THE STRUCTURE OF PROKARYOTIC AND EUKARYOTIC. EUKARYOTIC CELLS: They are large and complex, and have membranous organelles. The genetic material is found in the nucleus. The cell membrane transports and exchanges molecules between the cell and its environment. It contains cytosol, cytoskeleton, organelles and ribosomes. Proudly made by Jose Antonio Luna 27 Nucleoplasm: liquid similar to cytoplasm. Chromatin: genetic material- DNA and Histones. Nucleolus: spherical structure which is involved in the synthesis of ribosomes. Nuclear envelope is made uo of two membranes and has pores that allow molecules to move. NUCLEUS. Nucleus: which contains genetic material, is the control centre of the cell. It can be considered a special type of organelle. Proudly made by Jose Antonio Luna 28 4. ANIMAL AND PLANT CELLS. Animal cells. They are very complex and have many internal areas with different functions. CELL STRUCTURE. There are many different types of cells, but they all have the same THESE ARE THE MAIN PARTS THEY HAVE IN COMMON: basic structure. The membrane is a thin layer that separates the cell from the external environment. The substances necessary for nutrition can pass through it into the cell and waste products can pass out of the cell. Proudly made by Jose Antonio Luna 29 4. ANIMAL AND PLANT CELLS. Proudly made by Jose Antonio Luna 30 4. ANIMAL AND PLANT CELLS. The cytosol is the semi-liquid interior of the cell. It contains biological molecules that are needed to carry out the biochemical reactions that keep the cell alive. Proudly made by Jose Antonio Luna 31 4. ANIMAL AND PLANT CELLS. The cytoskeleton is a set of protein filaments and microtubules. Proudly made by Jose Antonio Luna 32 4. ANIMAL AND PLANT CELLS. The centrioles. They form part of the centrosome. It is composed of microtubules and they are important during cell division. Proudly made by Jose Antonio Luna 33 4. ANIMAL AND PLANT CELLS. The Genetic material contain the information necessary to control cellular activity and to give the cell its specific characteristics. Proudly made by Jose Antonio Luna 34 4. ANIMAL AND PLANT CELLS. CELL DIFFERENTIATION. It is the process by which a less specialised cell becomes more specialised to perform particular functions. Proudly made by Jose Antonio Luna 35 4. ANIMAL AND PLANT CELLS. Plant cells. -They don´t have centrioles. Instead of the centrosome of animal cells, plant cells have a microtubule-organising centre (MTOC) without centrioles. -They have a cell wall of cellulose. The walls have holes called plasmodesmata. Proudly made by Jose Antonio Luna 36 4. ANIMAL AND PLANT CELLS. Plant cells. -They have chloroplasts. -Large vacuoles. Proudly made by Jose Antonio Luna 37 THE ORIGIN OF EUKARYOTIC CELLS: SYMBIOGENESIS. The theory of Endosymbiosis explains the origin of chloroplasts and mitochondria and their double membranes. This concept postulates that chloroplasts and mitochondria are the result of years of evolution initiated by the endocytosis of bacteria and blue-green algae. According to this theory, blue green algae and bacteria were not digested; they became symbiotic instead. Proudly made by Jose Antonio Luna 38 THE ORIGIN OF EUKARYOTIC CELLS: SYMBIOGENESIS. •Mitochondria and chloroplasts are similar in size and morphology to bacterial prokaryotic cells. •Mitochondria and chloroplasts divide by binary fission, just as bacteria do, and not by mitosis as eukaryotes do. •Mitochondria and chloroplasts have their own DNA and their own ribosomes. •Organelle ribosomes are more similar in size to prokaryotic ribosomes. •Mitochondria arise from preexisting mitochondria; chloroplasts arise from preexisting chloroplasts. •Many antibiotics that kill or inhibit bacteria also inhibit protein synthesis of these organelles. Proudly made by Jose Antonio Luna 39 4. TYPES OF CELL. There is a great variety of cell types. They can be classified according to their size, shape and complexity. 1)CELL SIZE. Cells are measured in micrometres. The size of cells varies. Proudly made by Jose Antonio Luna 40 4. TYPES OF CELL. There is a great variety of cell types. They can be classified according to their size, shape and complexity. 2)CELL SHAPE. Cells can be a variety of shapes which are related to their function. They can be anything from spherical or star-shaped. Plant cells are geometrically shaped while animal cells are often irregularly shaped. Proudly made by Jose Antonio Luna 41 4. TYPES OF CELL. 2)CELL SHAPE. Proudly made by Jose Antonio Luna 42 4. TYPES OF CELL. There is a great variety of cell types. They can be classified according to their size, shape and complexity. 3)CELL COMPLEXITY. There are two types of cell according to their complexity: prokaryotic and eukaryotic cells. Prokaryotic cells are simpler than eukaryotic cells. Only bacteria and Archeae have prokaryotic cells. All other organisms have eukaryotic cells. Proudly made by Jose Antonio Luna 43 4. TYPES OF CELL. Proudly made by Jose Antonio Luna 44 ACTIVITIES. PAGE 82. 2, 3, 4, 5 . Proudly made by Jose Antonio Luna 47 5. STRUCTURES AND ORGANELLES IN EUKARYOTIC CELLS Eukaryotic cells appeared later in the evolution process than prokaryotic cells. They are more developed cells and as a consequence, have several advantages over prokaryotic cells. ORGANELLES are structures that consists of a space that is usually enclosed by a membrane. They are adapted and specialised to perform specific functions. There are two main groups of organelles:organelles with membranes or without membranes. Proudly made by Jose Antonio Luna 48 ORGANELLES THAT PROCESS NUTRIENTS. A ORGANELLES WITH MEMBRANES. Proudly made by Jose Antonio Luna 49 5. EUKARYOTIC CELLS. Organelles that process nutrients. THE ENDOPLASMIC RETICULUM. It made up of a complicated network of tubes and vesicles. It makes and transports various substances such as lipids and proteins. Proudly made by Jose Antonio Luna 50 5. EUKARYOTIC CELLS. Organelles that process nutrients. -Rough Endoplasmic reticulum. It has ribosomes which make proteins and pass them to the Golgi apparatus. -Smooth endoplasmic reticulum DON´T have ribosomes but produce fats and eliminate toxins. Proudly made by Jose Antonio Luna 51 5. EUKARYOTIC CELLS. Organelles that process nutrients. THE GOLGIS APPARATUS is an organelle made up of vesicles and flattened sacs. It takes the substances from the endoplasmic reticulum which modifies and sends them through the vesicles to be delivered to other places within the cell. Proudly made by Jose Antonio Luna 52 5. EUKARYOTIC CELLS. Organelles that process nutrients. THE GOLGIS APPARATUS Proudly made by Jose Antonio Luna 53 5. EUKARYOTIC CELLS. Organelles that process nutrients. LYSOSOMES AND PEROXISOMES, are tiny vesicles that contains enzymes that can digest large molecules. Lysosomes carry out intracellular digestion and peroxisomes control different oxidation reactions. Proudly made by Jose Antonio Luna 54 5. EUKARYOTIC CELLS. Organelles that process nutrients. VACUOLES, are structures that store various substances, including nutrients and water. They are bigger and more numerous in plant cells than in animal cells and can occupy up to 80% os a plant cell´s total volume. Proudly made by Jose Antonio Luna 55 5. EUKARYOTIC CELLS. MITOCHONDRIA, are tube-shaped with a double membrane. The mitochondrial matrix contains genetic material, ribosomes and enzymes. Mitochondria are found in all eukaryotic cells. Mitochondria are the energy provides in eukaryotic cells, using cellular respiration. Proudly made by Jose Antonio Luna 56 5. EUKARYOTIC CELLS. Proudly made by Jose Antonio Luna 57 5. EUKARYOTIC CELLS. CHLOROPLASTS are organelles with a double membrane. They contain thylakoids, which contain chlorophyll, the pigment that gives them their characteristic green colour. Photosynthesis occurs in the chloroplasts. They convert the radiant energy from the sun into chemical energy. This is then used to convert inorganic molecules such as carbon dioxide into organic molecules like glucose. Proudly made by Jose Antonio Luna 58 ACTIVITIES. PAGE 75. 15, 16, 17, 18. Homework. Proudly made by Jose Antonio Luna 59 B. ORGANELLES WITHOUT MEMBRANES. Organelles without membranes are ribosomes, cytoskeleton, the centrosome and cilia and flagella 1) Ribosomes. They are composed of RNAr and proteins. They can be free in the cytoplasm or in ER. Ribosomes translate mRNA in order to synthetise proteins. Proudly made by Jose Antonio Luna 60 B. ORGANELLES WITHOUT MEMBRANES. 2) THE CYTOSKELETON. It is a network of protein, which supports the cytoplasm and is responsible for cell movement. It is made up of: -Microfilaments made of actin which participate in muscle contraction and cytokinesis in cell division. -Intermediate filaments, which are made up of different proteins and help maintain cell shape. -Microtubules. Make up the mitotic spindle, cilia and flagella . Proudly made by Jose Antonio Luna 61 Some eukaryotic cells are capable of movement. Movement can be produced in two different ways: Using cilia and flagella. Cilia are shorter and more numerous than flagella. Proudly made by Jose Antonio Luna 62 5.3 CELLS THAT MOVE. Some eukaryotic cells are capable of movement. Movement can be produced in two different ways: Using cilia and flagella. Cilia and flagella are organelles that can move. They are formed from the protein fibres of the cytoskeleton. They are external to the cell. Proudly made by Jose Antonio Luna 63 CENTROSOME. Includes two centrioles composed of microtubules. It is resposible for organising microtubules in animal cells and forming spindles during cell division. Proudly made by Jose Antonio Luna 64 DEVELOPMENT OF BASIC COMPETENCES Page 83. Proudly made by Jose Antonio Luna 65