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Transcript
CELLS AND TISSUES
Cell Parts
Suzanne D'Anna
1
Basic Cell
defined as the structural and functional unit
of all living things
- as small as 1/1000th of an inch (bacteria)
- as large as 4 feet (certain nerve cells)
 Shape:
- disc shaped, thread-like, cube-like, etc.
 Functions:
- protection, hormones, chemical
regulation, gas exchange, cleanse blood

Suzanne D'Anna
2
Main Regions of a Cell
plasma (cell) membrane
 cytosol (cytoplasm)
 organelles
- specialized highly
organized structures for
specific cellular activities
 inclusions
- temporary structures

Suzanne D'Anna
3
Plasma (cell) Membrane
outer layer of the cell
 fragile barrier
 separates internal components of the
cell from the external environment
 contains cell contents
 two lipid layers - protein molecules are
suspended between lipid layers

Suzanne D'Anna
4
Plasma (cell) Membrane
(cont.)
unique structure which determines
which substances enter or leave the cell
 Consists of:
- phopholipids
- cholesterol
- proteins

Suzanne D'Anna
5
Functions of Membrane
Proteins
channels
 enzymes
 transportation of substances across
membrane
 receptor sites for hormones,
neurotransmitters, or nutrients
 cytoskeleton anchors
 cell identity markers

Suzanne D'Anna
6
Cytoplasm
outside nucleus
 inside plasma membrane
 site of most cellular activities
 Major elements include:
- cytosol
- inclusions
- organelles

Suzanne D'Anna
7
Cytosol
viscous, transparent, gel-like
 75% H2O + solid components:
- proteins, carbohydrates, lipids, and
inorganic substances
- inorganic substances and smaller
organic substances soluble in H2O
are present as solutes
- larger organic compounds are
found as colloids (semi-solid matrix)

Suzanne D'Anna
8
Organelles
little organs
 specialized structures
 characteristic appearances
 specific roles in growth, maintenance,
repair, and control
 chemically different with one another

Suzanne D'Anna
9
Nucleus

Three distinct components:
- nuclear membrane
- nucleoli
- chromatin
Suzanne D'Anna
10
Nucleus
(cont.)
largest organelle in the cell
 usually oval or spherical - conforms to
shape of the cell
 contains genetic material (DNA)
 controls cellular functions
 directs cellular activities
 surrounded by nuclear membrane

Suzanne D'Anna
11
Nuclear Membrane
double layer
 bound to nucleus
 encloses nucleoplasm in which nucleoli
and chromatin are suspended
 has large pores

Suzanne D'Anna
12
Nucleoli
little nucleus
 dense body
 composed mostly of RNA and protein
 ribosome production (migrate through
pores in nuclear envelope and enter
cytoplasm)
 disappear during cell division and
reappear in daughter cells

Suzanne D'Anna
13
Chromatin
loosely coiled fibers of DNA and
associated proteins
 before cell division DNA duplicates,
chromatin fibers coil and shorten to form
chromatids
 one of two spiral filaments joined at the
centromere which make a chromosome

Suzanne D'Anna
14
Ribosomes
tiny, round dark bodies
 sites of protein synthesis
 contain ribosomal RNA (rRNA)

Suzanne D'Anna
15
Endoplasmic Reticulum
system of membrane-enclosed tubules
or channels that coil and twist; called
cisterns
 continuous with nuclear envelope
 serves as minicirculatory system
 provides surface area for chemical
reactions
 Two types:
- granular and agranular

Suzanne D'Anna
16
Endoplasmic Reticulum
Granular
rough
 studded with ribosomes which synthesize
protein
 temporary storage area
 together with Golgi body it synthesizes
and packages molecules that will be
excreted from the cell

Suzanne D'Anna
17
Endoplasmic Reticulum
Agranular (smooth)
site of fatty acid, phospholipid, and
steroid synthesis
 inactivates or detoxifies chemicals such
as alcohol, pesticides, and carcinogens

Suzanne D'Anna
18
Golgi Apparatus
(body or complex)
 stacks of flattened sacs with bulges at
ends
 located close to nucleus
 modifies, packages, and secretes
proteins and lipids
 as proteins accumulate in sacs, the
sacs swell; swollen sac pinches off to
form vesicles that travel to cell
membrane
Suzanne D'Anna
19
Route of Proteins for Export
ribosomes
rough ER
transport
vesicles
Golgi body
vesicles
release to exterior of cell
Suzanne D'Anna
secretory
20
Lysosomes
membrane-enclosed vesicles
 formed in Golgi body
 contain powerful digestive enzymes (as
many as 40) responsible for breaking
down molecules
 can also digest worn-out cell structures
(autophagy) and foreign substances

Suzanne D'Anna
21
Peroxisomes
membrane sacs similar to lysosomes
but smaller
 contain enzymes that use molecular
oxygen to oxidize organic substances
 detoxify potentially harmful substances
that may enter the bloodstream
(e.g., free radicals)
 especially important in liver and kidneys

Suzanne D'Anna
22
Mitochondria
(powerhouse of the cell)
sausage-shaped fluid filled sacs
 double membrane wall
 outer wall is smooth
 inner wall - series of folds called cristae
 cristae provide surface area for cellular
respiration (only occurs if O2 is present)
 enzymes on cristae catalyze reactions
that generate ATP

Suzanne D'Anna
23
Cytoskeleton
responsible for cell movement and for
movement of organelles and chemicals
within the cell
 Network of protein structures:
- microfilaments
- microtubules
- intermediate filaments

Suzanne D'Anna
24
Microfilaments
rod-like structures
 formed from the protein actin
 in muscle tissue - actin filaments (thin)
and myosin (thick) slide past one
another to produce contraction
 in non-muscle - actin filaments support
and shape

Suzanne D'Anna
25
Microtubules
larger than microfilaments
 straight, slender cylindrical structures contain the protein tubulin
 support and shape cells
 movement of substances

Suzanne D'Anna
26
Intermediate Filaments
medium size
 strong and tough
 provide structural reinforcement

Suzanne D'Anna
27
Centrosome
cytoplasmic material
 within centrosome is pair a of rodshaped bodies called centrioles
- lie at right angles to each other
- during cell division, centrioles direct
formation of mitotic spindle
- like mitochondria, they contain DNA
and control self replication

Suzanne D'Anna
28
Cilia
minute projection extending from cell
surface
 contain ten pairs of microtubules
 act to move substances along cell surface
 beat rhythmically to move fluids or
particles over cell surface

Suzanne D'Anna
29
Flagella
long whip-like projections extending
from free cell surface
 act to propel a cell
 contain ten pairs of microtubules
 tail of sperm is a flagellum

Suzanne D'Anna
30