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Date:
ID: A
Chapter t1 Pre-test
Multiple Choice
Identifi the choice that best completes the statement or snswers rhe question
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I
-
Which of the following is caused bv a dominant allele?
a. Huntington'sdisease
b,
c.
d.
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Tay-Sachs disease
none ofthe above
Which of the following geno\pes result in the same phenotype?
c,
a. i'l a,Jd,1'1'
b- Plts and lBt
c. FP andl F
d. Jtst and ii
If
a man
wth blood tlpe A
and a woman with blood type B produce an offspring, what might be the offspring's
a. ABorO
b. A, B,orO
c. ÀB,aB,orO
d. AB only
People who are hetero4ygous for sickle cell disease are generall¡r healthv because
they are resistanL to malaria.
they usually have some normal hemoglobin in tleir red blood cells.
a.
b.
c.
&eir abno¡¡al herncglobin usuatly dc*-sn't cause *ùeir ¡ed blccd cells to beccne
d.
they do not producæ abnormal hemoglobin.
sickle-shaped.
C,
c
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6.
Alleles found on the same ch¡omosomes
a. are dominantb- are never sçarated by recombinationc. are linked.
d- contain repetitive DNA.
Colorblindness is more common in males thal h females i¡ecause
fathers pass the allele for colorbli¡dness to their sons only.
the allele for colorblindness is located on tÀe Y chromosome.
the allele for colorblindness is recessive and located on the X chromosome.
males who a¡e colorblind have two copies ofthe allele for colorblindness.
a.
b.
c.
d.
Which of the following statements is true?
a.
b.
c.
d.
Females cannot have hemophilia.
The father of a colorblind boy may be colorblind.
A sex-linked allele cannot be dominant
The mother of a colorblind boy must be colorblind.
ID: A
Name:
_,L 8. The failure ofchromosomes to separate during meiosis is called
a- nondisjunction,
b. X-chromosomeinactivation.
c- Tumer's syndrome.
d- Dovm syndrome9.
10.
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Ifnondisjunction occurs during meiosis,
å.
bc.
d.
The purpose ofgene therapy is to
a.
b.
c.
ci.
tt
.
iorm instead oi four.
gametes
may have an extra copy of some genes.
some
the chromaúds do not separate.
it occurs during prophase.
or'¡iy ¿wo gaflie'res ïnay
cure genetic Cisorders.
determine the sequences ofgenes.
remove mutations from genes.
change dominant alleles to recessive aileies.
which of the following is the first step in gene úerapy?
a. splicing the normal gene to viral DNA
b. allowing recombinant vinses to infect human cells
c.
d.
using restriction enãÃnes to cût out the normal gene fiom DNA
ident$-ing the ftr:lç gene that causgs the diseâse
Modified Truey'False
Indicate whether the statement is true or false-
f
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In a human karyotype.
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Ifþße,
change the identifed word or phrase to make the statement true
ofthe chromosomes are autosomes.
ifa
mother is represented by a shaded circle and a father is represented by a shaded square, their
children c¿Dnot be represenæd by half-shaded circles or squares.
Úr a pedigree,
A person who has Down s¡.ndrome has two copies of cfuomosome 21.
Name:
ID: A
Other
USING SCIENCE SKILLS
The pedigree shows the inheritance offree earlobes and ætached earlobes in five generæions ofa familyAttached ea¡lobes are caused by a rec€ssive allete (/. Flalf-shaded symbols a¡e NOT used in this pedigree to
shou' carriers ofthe allele.
Att".tretl
______ô
eadobes eartobes
i
--fte"
I
I
_
Drrr4ls
f---_-__ ------_t
J--LI
Lt u
f
lr'¿¿"fl
tt
lFemae
Q
a
I
I
I
Lr--r---1J
67819
!
T--T_--l
â
1o 11 =-!a
12 l13
Ë
¡ir
14
Figure 14-2
15. Inferring
Is
indiú{al
a. homoz¡,gous
tu
lli.oïlr:
(
2 in Figure l4-2 homozygous or heterorygous for free earlobes?
b-äeteroz-vgous c. both d. neither
a.Tnîrö"
I4-2, how many child¡en of individuals 4 and 5 have atrached earlobes?
17. Predicting Predict the genotype and phenot)?e of individual 14 in Fþre l4-2.
a- heterozygous and attached earlobes
h hctcrn^,on"c ¡n¡! Êæ p¡¡ lnhec
z^----- --r Þ--(c,þomo.rygous recessive (ff) and attached earlobes.
homozygous domina-ot (FF) and auached ea¡lobes.
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