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DNA, RNA, Protein Graphic Organizer DNA Shape: Structure: Bases: Base Pairings: RNA Shape: Structure: Bases: Base Pairings: Three Types of RNA mRNA: rRNA: tRNA: Proteins Replication: Transcription: Translation: Example #1 Try on your own: Replication DNA (DNA) T A C C T A G A C T A T mRNA tRNA (Transcription) (Translation) Amino Acid Instructions: 1. Use the DNA code to create your mRNA code. 2. Use the mRNA code to create your tRNA code. 3. Use the mRNA code and the Genetic Code to determine your amino acids. 1. DNA T C C G C G C A G A G C T A G A C A A G A C G G T A C T G A mRNA tRNA Amino Acids 2. DNA mRNA tRNA Amino Acid Sickle Cell DNA/RNA Mutation Worksheet Sickle cell anemia is a disease that is passed down through families. Normal red blood cells are shaped like a disc, while sickle blood cells are shaped in a crescent shape. Sickle cell anemia is caused by an abnormal type of hemoglobin. Hemoglobin helps carry oxygen throughout the body. Sickle cell anemia is caused by a point mutation in the genetic code. 1. AUG-GUU-CAU-CUG-GUG-GAA-GAG-CAC-GUA-GAA-CAC-UAG The above RNA codons code for a person who has sickle cell anemia. Translate the above RNA codons into amino acids. One codon translates to one amino acid. - - - - - - - - - - - - 2. The following amino acid sequence is sequence for normal red blood cells Methionine – Valine – Histidine – Leucine – Glutamine – Glutamine – Glutamine – Histidine – Valine – Glutamine – Histidine – STOP What is the difference between the amino acid sequence in question 1 and the amino acid sequence in question 2? What is the correct RNA codon sequence for someone with normal red blood cells?