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Site map of the walk-through cell the cell AN AIR OBJECT TO FEEL AND EXPLORE 2 8 4 6 5 1 8 Photo of the giant cell: diameter 6 m, height 3.5 m 7 3 The following system was created to describe very long and very short lengths: 1 000 000 000 1 000 000 1 000 100 10 m m m m m = = = = = 1 m 0.1 0.01 0.001 0.000 001 0.000 000 001 0.000 000 000 001 m m m m m m 1 Gm 1 Mm 1 km 1 hm 1 dam 1 gigameter 1 megameter 1 kilometer 1 hectometer 1 decameter basic unit 1 meter = = = = = = 1 dm 1 cm 1 mm 1 µm 1 nm 1 pm 1 decimeter 1 centimeter 1 millimeter 1 micrometer 1 nanometer 1 picometer 1 km = 1093.61 yds, 1 meter = 1.09361 yds 1 cm = 0.39370 inches; 1 mm = 0.03937 inches “If the DNA from all the cells in the human body were stretched out in a line, it would reach 1000 times as far as the distance of the Earth from the Sun.” The “walk-through cell” is a joint project of the University of Basel and Interpharma. 1 Cell nucleus cell – this is 1 Zellkern “Control center” of5 the Ribosom Zellmembran 6 Golgi-Apparat where23 genetic information (DNA) is stored. Mitochondrium 7 Lysosom 4 Endoplasmatisches 8 Vesikel 2 Cell membrane TheRetikulum “choosy” cover – it controls the exchange of substances between the cell and its surroundings. 3 Mitochondrium “Powerhouse” of the cell – it is here that energy is released from nutrients and made available to the cell. 4 Endoplasmic reticulum (ER) “Canal system” of the cell – this is where biomolecules are formed, stored and then forwarded. 5 Ribosome “Nanomachine” in the cell – this is where proteins are made in huge amounts. 6 Golgi apparatus “Distribution center” of the cell – it is here that cell products are finished, sorted, packed and delivered to their destinations. 7 Lysosome “Gut” and “waste bin” of the cell – this is where surplus cell material is digested. 8 Vesicle “Means of transport” for the cell – it contains substances that it transports within the cell. Welcome The “walk-through cell” is the model of a human cell magnified approx. 300,000 times. This is about the same ratio of the size of the small hot-air balloon versus the size of the Earth. The model shows in as much detail as possible the inner structure of the cell and its subdivision into different areas and structures. The cell invites exploration: When you feel it and look more closely at its constituent parts, you find out a lot of details about the various parts and the cell as a whole. Individual cell structures are shown somewhat larger or smaller than other elements either for practical purposes or for didactic reasons. The ratio of 1:300,000 corresponds to the size of a small hot-air balloon (diameter 42.3 meters) versus the size of the Earth (diameter approx. 12,700 kilometers). www.facebook.com/TheGiantCell http://thegiantcell.blogspot.com www.thecell.ch, www.diezelle.ch The cell – basic building block of all life Cells are the smallest units of life. The simplest living creatures consist of just one cell (e.g., ameba), whereas large plants and animals are made up of several billion cells. In the case of humans the figure is about 100 billion – that is 100,000,000,000,000 cells! Our body contains many different types of cell, and every cell performs a very specific task. The interior of the cell can be likened to a complicated factory in which thousands of chemical reactions take place. Organism Organism Most cells are quite small. For example, if you enlarge a blood cell 1000 times, it will be about as large as a grain of rice. Because cells are so tiny, they are measured not in centimeters or millimeters, but in micrometers. Most animal and human cells measure 10–50 micrometers. “Our body produces about 300 million new cells every minute – of these, about 2.5 million cells are red blood cells.” Our body grows as a result of cells dividing and each of these new cells then growing as large as the original cell and dividing in turn. We are in constant need of new cells to replace cells that have worn out or died. The human body consists of more than 200 different cell types, all of which are basically identical in structure. consists mainly of proteins. Embedded in the cytoplasm, the cell contains various structures known as organelles (from Greek organon = tool or organ). The name indicates that these organelles perform very specific, vital functions – rather like an organ in the body. For example, certain organelles supply the energy that other organelles need for the production of vital nutrients. So the cell is a “joint operation” of its various constituent parts: If one is separated from another, they cannot work on their own. “The life of the cells varies depending on their activity: The cells that line our gut, for example, live for about 1 to 2 days. Bone cells can live for as long as 15 to 20 years.” In a complete cell, all the characteristic features of life are reflected, such as growth, movement, metabolism, excitability and reproduction. All cells consist of a jelly-like cytoplasm that is covered by a thin cell membrane. Apart from water and substances dissolved in the water, cytoplasm Organ system Organ system Organ Organ Tissue Tissue Cell Cell Organelle Organelle Large Large molecule molecule Small Small molecule molecule 1 meter 1 meter 1 centimeter 1 centimeter 0.10.1 millimeter millimeter 1 micrometer 1 micrometer Organizational levels of the human body Graphics: © vasp datatecture GmbH, Zürich / Ernst Klett Verlag, Stuttgart 1 nanometer 1 nanometer Atom Atom