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CHAPTER 15 Name________________________ THE CHROMOSOMAL BASIS OF INHERITANCE 15.1 Relating Mendelian Inheritance to the Behavior of Chromosomes 1. Explain how the observations of cytologists and geneticists provided the basis for the chromosome theory of inheritance. 15.2 Sex Chromosomes 2. Explain why sex-linked diseases are more common in human males. 3. Describe the inheritance patterns and symptoms of color blindness, Duchenne muscular dystrophy, and hemophilia. 15.3 Linked Genes 4. Distinguish between linked genes and sex-linked genes. 5. Explain why linked genes do not assort independently. Explain how crossing over can unlink genes. 6. Explain why Mendel did not find linkage between seed color and flower color, despite the fact that these genes are on the same chromosome. 7. Explain the effect of multiple crossovers between loci. 15.4 Errors and Exceptions in Chromosomal Inheritance 8. Explain how nondisjunction can lead to aneuploidy. 9. Distinguish among deletions, duplications, inversions, and translocations. 15.5 Exceptions to Standard Chromosome Theory 10. Define genomic imprinting. Describe the evidence that suggests that the Igf2 gene is maternally imprinted. Learning Objectives for Campbell/Reece Biology, 8th Edition, © Pearson Education, Inc. 1 of 1