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THE CELL CYCLE: MITOSIS OVERVIEW: • The cell theory states that all cells come from preexisting cells. (Virchow) • New cells are made through cell division. • The cell cycle is the sequence of growth and division of a cell. INTERPHASE • Majority of cell’s life is spent in Interphase. • Cell grows in size. • Genetic material (DNA) is replicated (S Phase of Interphase) in preparation for division. INTERPHASE G1 phase-cell grows and protein production is high G0 phase-optional…no cell division S phase-DNA synthesis and replication of genetic material G2 phase-Centrioles replicate; cell prepares for division MITOSIS (M PHASE) • After Interphase, cells enter Mitosis. • Mitosis is the process by which 2 new identical cells are formed (each with its own complete set of chromosomes). 1. PROPHASE • First and longest phase of Mitosis. • Long, stringy chromatin coils up into visible chromosomes. • Nuclear membrane disappears. • Spindle fibers form attached to the centrioles. (animal cells) METAPHASE • Chromosomes move to equator (middle) of the cell and line up. ANAPHASE • The centromeres are split and the sister chromatids are pulled apart to opposite sides of the cell. TELOPHASE • Two new daughter cells are formed. The cells separate completely in a process called cytokinesis which is the end of mitosis. SUMMARY Mitosis