CLICKER QUESTIONS For CAMPBELL BIOLOGY, NINTH EDITION Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson Chapter 12 The Cell Cycle Click to edit Master title style Click to edit Master subtitle style Questions prepared by Louise Paquin McDaniel College © 2011 Pearson Education, Inc. Prokaryotic Division Why don’t prokaryotic cells need to go through the same cell cycle as eukaryotic cells? © 2011 Pearson Education, Inc. S Phase How might you prove experimentally that DNA replication (and therefore the replication of chromosomes) happens during the S phase of the cell cycle and not during mitosis? © 2011 Pearson Education, Inc. Chromosomes in the Cell Cycle At what part of the cell cycle would you see a chromosome that looks like this? Give your reasons. © 2011 Pearson Education, Inc. Evolution What do the differences among the division of these cells demonstrate? © 2011 Pearson Education, Inc. Kinetochore Which of the following best describes the kinetochore? a) a structure composed of several proteins that associate with the centromere region of a chromosome and that can bind to spindle microtubules b) the centromere region of a metaphase chromosome at which the DNA can bind with spindle proteins c) the array of vesicles that will form between two dividing nuclei and give rise to the metaphase plate d) the ring of actin microfilaments that will cause the appearance of the cleavage furrow e) the core of proteins that forms the cell plate in a dividing plant cell © 2011 Pearson Education, Inc. Rate of Mitosis If you were to examine a sample of connective tissue cells from a small but adult mammal and a second sample from a fetus of the same species, in which would you expect to find more cells undergoing mitosis? Why? © 2011 Pearson Education, Inc. Regulation of the Cell Cycle A. What would you expect to happen if you fuse a cell in S with a cell in G1? Why? B. What would you expect to happen to a nucleus from a G1 cell if it is introduced into an enucleated M cell? Why? © 2011 Pearson Education, Inc. Regulation Which of the following would need to be present to produce a realistic signal to control the cell cycle? (More than one may be required.) a) a set of molecules that are sensitive to fluctuations in the abundance of regulators b) protein kinases c) molecules that activate kinases d) molecules that degrade activators e) All of the above. © 2011 Pearson Education, Inc. Cancer Cells At which part of the cell cycle would you expect that a change in regulation could result in cancer? Provide a reason for your answer. © 2011 Pearson Education, Inc.