* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Immunology Male et al., 8 th Ed. 2013.
Germ theory of disease wikipedia , lookup
Gluten immunochemistry wikipedia , lookup
Inflammation wikipedia , lookup
Monoclonal antibody wikipedia , lookup
Adoptive cell transfer wikipedia , lookup
Rheumatoid arthritis wikipedia , lookup
Complement system wikipedia , lookup
Sociality and disease transmission wikipedia , lookup
Immunocontraception wikipedia , lookup
Sjögren syndrome wikipedia , lookup
Vaccination wikipedia , lookup
DNA vaccination wikipedia , lookup
Herd immunity wikipedia , lookup
Adaptive immune system wikipedia , lookup
Molecular mimicry wikipedia , lookup
Cancer immunotherapy wikipedia , lookup
Immune system wikipedia , lookup
Polyclonal B cell response wikipedia , lookup
Social immunity wikipedia , lookup
Innate immune system wikipedia , lookup
Immunosuppressive drug wikipedia , lookup
Autoimmunity wikipedia , lookup
An-Najah National University Faculty of Medicine & Health Sciences Department of Pathology, Immunology and Microbiology Immunology7105306 (Compulsory course) Course Credit Hours: 3 Students Workload: 3 Teacher workload: 3 PREREQUISITES General Microbiology 7105301 INSTRUCTORS Alaeddin Abu-Zant, PhD Microbiology and Immunology Office phone: 2571 Email: [email protected] TEXT BOOK: Immunology Male et al., 8th Ed. 2013. Cellular and Molecular Immunology Abbas et al., 7thEd. 2012. Basic Immuniology, Abbas et al 2012 REFERENCES Published scientific papers. Murphy et al. Janeway's Immunobiology, 8th Ed. 2011 ADDITIONAL MATERIALS OR EQUIPMENT NEEDED FOR THE COURSE Internet resources SUPPLEMENTARY MATERIALS Reviews and articles from the international journals on the web The references in the library of the University Commercial Immunology Kit manuals COURSE DESCRIPTION This course concentrates on the basic and clinical science of the immune system and its relationship to other sciences and biological systems of mammals. This course will concentrate on function-structure relationship of the immune system and its components such as the lymphoid tissue and cells, the development and function of the immune system, as well as the clinical science of the immune system and its role in the prevention, causation and diagnosis of human diseases such as cancer, autoimmune disease and other topics. . INTENDED LEARNING OUTCOMES After this course the students should know the basic elements of immunology namely lymphocyte biology, antigen presentation, humoral, cellular, mucosal immune responses, inflammation, complement and cytokines. The student should be familiar with different categories of diseases related to the immune system highlight the hypersensitivity reactions, autoimmunity and immunodeficiency diseases. Intended Learning Outcomes of Course (ILOs) a- Knowledge and Understanding: a.1. Recognize the normal immune system.. a.2. Describe the mechanisms of innate immunity. a.3. Recognize antigens, Immunoglobulins and describe antigen - antibody reactions.. a.4. Describe antigen presentation and the major histocompatibility complex.. a.5. Identify inflammation and the inflammatory response. a.6. Recognize the humoral and cell mediated immune response a.7. Describe the hypersensitivity reactions and immunodeficiency diseases. a.8. Explain Immune tolerance and principles of autoimmunity a.9.Describe the basics of Transplantation and tumor immunity b- Intellectual Skills. b.1. Interpret the results of serological tests. b.2. Recognize the warning signs of immune disorders.. b.3. Recognize the mechanisms and type of graft rejection. b.4. Recognize the mechanism of autoimmune diseases. c- Professional and Practical Skills: c.1. Interpret different immunological reports. c.2. Distinguish methods of tissue typing. c.3. Distinguish the methods and tools used in clinical immunology. c.4. Evaluate results of different immunological tests. d- General and transferable skills: d.1. Search Internet data base for diagnostic measures in microbiology. d.2. Independently learning d.3. Work in a team d.4.Respect assisting personal d.5. Appreciate team work in seminar. COURSE OUTLINE AND CALENDER TOPICS SECTION I:Componenets of the Immune System Introduction to the Immune System Cells, Tissues and Organs of the Immune System Antigens and antibodies Complement T cell Receptors and MHC Molecules HOURS FIRST HOUR EXAM Section II: Modes of the Immune Response Mechanisms of Innate Immunity Inflamation Mononuclear Phagocytes in Immune Defense Antigen presentation Cell- Mediated Cytotoxicity T-cell activation Cell Cooperation in the Antibody Response Regulation of the Immune Response Immune Responses in Tissues 25% SECOND HOUR EXAM Section III: Defense Against Infectious Agents Immunity to Viruses Immunity to bacteria and Fungi Immunity to Protozoa and Worms Primary Immunodeficiencies AIDS, Secondary Immunodeficiencies and Immunosuppression Vaccination 25% Section IV: Immune Responses Against Tissues Immunological Tolerance Autoimmunity and Autoimmune Disease Transplantation and Rejection Immunity to Cancers Section V: Hypersensitivity Hypersensitivity Type I ( Immediate Type) Hypersensitivity Type II Hypersensitivity Type III Hypersensitivity Type IV FINAL EXAM Total 2 4 4 3 3 1 2 1 2 1 2 2 1 1 1 1 1 2 2 1 1 1 2 2 1 1 40% 45 hours TEACHING AND LEARNING METHODS: Tool Lectures Case study, small group discussion sessions and seminars. Micro project (e.i. Review article) Gateway Science Workshop Purpose To explain the theoretical knowledge for each topic To apply the knowledge on a real case, answer the questions of the students and evaluate their knowledge To teach the students how to examine the references and periodicals ILOs a.1, a.2, a.3, a.4, a.5,a.6, a.7, a.8, a.9 b.1, b.2, b.3, b.4, d.3, d.4, d.5 peer-led program designed to enhance students' learning d.1, d.2, d.3, d.4, d.5 TEACHING RESOURCES: White board One lecture hall in the department. Overhead projector Computer COURSE POLICIES Class attendance (Participation) Student must attend at least 75% of lecture Moodle participation Case presentation GRADING: First & Second Exams 50% Final Exam 40% Presentation 10% d.1, d.2, a.4, a.5, a.7, a.8, a.9