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Clinical Neuroscience
by Kelly Lambert and Craig Howard Kinsley
Chapter 13
Psychoneuroimmunology
Fundamentals of Immune System
Function: The Body’s Federal Bureau
of Investigation
 The
Body’s Most-Wanted Invaders
 Innate Immunity: The Immune System’s
Front-Line Defense
Fundamentals of Immune System Function: The Body’s
Federal Bureau of Investigation (cont.)
 Acquired
Immunity: Cells That Plan for the
Future
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
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Antibodies and B cells
T cells
Contrasting acquired immune defense
strategies
Fundamentals of Immune System Function: The Body’s
Federal Bureau of Investigation (cont.)
 Major
Histocompatibility Complex and
Information Dissemination
 When Good Cells Turn Bad
Integrative Operations:
Immunological and Nervous System
Communication
 Conditioning
the Immune System: A
Serendipitous Discovery
 Additional Pieces of the Neuroimmune
Puzzle
Integrative Operations: Immunological and Nervous System
Communication (cont.)
 Stress:
Mediator Between the Immune and
Neural Agencies
 Sickness Behavior and Its Role in
Maintaining Health
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

Fever
Loss of appetite
Role of cytokines
Putting the “Psych” in
Psychoneuroimmunology
 Psychological
Factors Leading to
Compromised Immune Function
 Psychological Factors Leading to
Enhanced Immune Function
Summary