The Effect of Chitin Size, Shape, Source and Purification Method on
... In the present work there was a specific interest in reporting the human immune responses to fungal chitin, since this is an understudied area of research. Exposure of whole C. albicans cells to hPBMCs results in the induction of a protective Th17 response [33]. Both IL-1β and IL-6 are two cytokines ...
... In the present work there was a specific interest in reporting the human immune responses to fungal chitin, since this is an understudied area of research. Exposure of whole C. albicans cells to hPBMCs results in the induction of a protective Th17 response [33]. Both IL-1β and IL-6 are two cytokines ...
The Role of Macrophages in the Placenta
... signaling is absent. Stimulation of macrophages with IL-4 and IL-13 (cytokines produced by induced CD4+ Th2 and CD8+ Tc2 cells, NK cells, basophils, mast cells, eosinophils) results in “alternative activation“ of macrophages . These “alternatively activated“ macrophages were first termed M2 macropha ...
... signaling is absent. Stimulation of macrophages with IL-4 and IL-13 (cytokines produced by induced CD4+ Th2 and CD8+ Tc2 cells, NK cells, basophils, mast cells, eosinophils) results in “alternative activation“ of macrophages . These “alternatively activated“ macrophages were first termed M2 macropha ...
VENEZUELAN EQUINE ENCEPHALITIS VIRUS REPLICON
... delivery. Here we demonstrate that following nonmucosal VRP vaccination, several markers of mucosal lymphoid tissues were present in the draining lymph node (DLN). This included the presence of antigen-specific polymeric IgA antibodies, upregulated expression of the α4β7 integrin on DLN lymphocytes, ...
... delivery. Here we demonstrate that following nonmucosal VRP vaccination, several markers of mucosal lymphoid tissues were present in the draining lymph node (DLN). This included the presence of antigen-specific polymeric IgA antibodies, upregulated expression of the α4β7 integrin on DLN lymphocytes, ...
The Role of Macrophages in Murine Intraocular - Ti
... et al. 2001). A special characteristic of intraocular melanomas is their hematogenous pathway of metastasis due to the absence of lymphatic vessels in the eye. The metastases show a predisposition to the liver and are rarely detected in the lungs or other sites (Singh, Shields et al. 2001). At the t ...
... et al. 2001). A special characteristic of intraocular melanomas is their hematogenous pathway of metastasis due to the absence of lymphatic vessels in the eye. The metastases show a predisposition to the liver and are rarely detected in the lungs or other sites (Singh, Shields et al. 2001). At the t ...
Immunobiology janeway - Mount Allison University
... therefore directly reflect the infections to which he or she has been exposed. Indeed, it quickly became clear that specific antibodies can be induced against a vast range of substances. Such substances are known as antigens because they can stimulate the generation of antibodies. We shall see, howe ...
... therefore directly reflect the infections to which he or she has been exposed. Indeed, it quickly became clear that specific antibodies can be induced against a vast range of substances. Such substances are known as antigens because they can stimulate the generation of antibodies. We shall see, howe ...
Untitled
... therefore directly reflect the infections to which he or she has been exposed. Indeed, it quickly became clear that specific antibodies can be induced against a vast range of substances. Such substances are known as antigens because they can stimulate the generation of antibodies. We shall see, howe ...
... therefore directly reflect the infections to which he or she has been exposed. Indeed, it quickly became clear that specific antibodies can be induced against a vast range of substances. Such substances are known as antigens because they can stimulate the generation of antibodies. We shall see, howe ...
The Role of RNase L in Thymic Homeostasis and Humoral Responses
... spleen size and antibody production in TD or TI antigen immunized RNase L-/- mice were severely altered. A combination of GM-CSF, a hematopoietic growth factor facilitating both humoral and cellular mediated immunities, and the antigen in immunization, augmented TD antigen-directed immune responses ...
... spleen size and antibody production in TD or TI antigen immunized RNase L-/- mice were severely altered. A combination of GM-CSF, a hematopoietic growth factor facilitating both humoral and cellular mediated immunities, and the antigen in immunization, augmented TD antigen-directed immune responses ...
Leukocyte surface antigen CD47
... 1996a). Upon binding to CD47 4N1K is shown to inhibit human Th1 T-cell differentiation by blocking production of IL12 (Avice et al. 2001). In the same study this effect was corroborated using human antibodies against CD47, showing that this peptide regulates CD47-mediated development of Th1 cells wi ...
... 1996a). Upon binding to CD47 4N1K is shown to inhibit human Th1 T-cell differentiation by blocking production of IL12 (Avice et al. 2001). In the same study this effect was corroborated using human antibodies against CD47, showing that this peptide regulates CD47-mediated development of Th1 cells wi ...
Outlines
... containing nerve fibers in primary and secondary lymphoid organs from which NPY can be released within the local immunological microenvironment. ...
... containing nerve fibers in primary and secondary lymphoid organs from which NPY can be released within the local immunological microenvironment. ...
Boundless Study Slides
... • mucous membranes Specialized epithelium for internal and semi-internal structures that usually secrete mucus and provide some barrier immune system function. • Natural Killer T cells A heterogeneous group of T cells that share properties of both T cells and natural killer (NK) cells, and recognize ...
... • mucous membranes Specialized epithelium for internal and semi-internal structures that usually secrete mucus and provide some barrier immune system function. • Natural Killer T cells A heterogeneous group of T cells that share properties of both T cells and natural killer (NK) cells, and recognize ...
Amal Ghonemy Metwali Abo Zekry_review
... squamous and the petrous parts of temporal bone .Between these two parts there is a sutural line that is normally obliterated but occasionally , a plate of a bone persist which is called korner's septum. When this septum is present it divides the mastoid process into superficial (squamous) portion a ...
... squamous and the petrous parts of temporal bone .Between these two parts there is a sutural line that is normally obliterated but occasionally , a plate of a bone persist which is called korner's septum. When this septum is present it divides the mastoid process into superficial (squamous) portion a ...
Immune Responses In Vitro and In Vivo Oligodeoxynucleotide for
... a phosphodiester ODN with a single copy of the optimal human CpG motif triggers ⬃60% of human peripheral blood B cells to proliferate and express high levels of CD86. We also demonstrated that this ODN, of sequence 2080, promotes growth, activation, and maturation of human peripheral blood dendritic ...
... a phosphodiester ODN with a single copy of the optimal human CpG motif triggers ⬃60% of human peripheral blood B cells to proliferate and express high levels of CD86. We also demonstrated that this ODN, of sequence 2080, promotes growth, activation, and maturation of human peripheral blood dendritic ...
Cenchao Shen - RMIT Research Repository
... qualify for any other academic award; the content of the thesis is the result of work which has been carried out since the official commencement date of the approved research program; any editorial work, paid or unpaid, carried out by a third party is acknowledged; and, ethics procedures and guideli ...
... qualify for any other academic award; the content of the thesis is the result of work which has been carried out since the official commencement date of the approved research program; any editorial work, paid or unpaid, carried out by a third party is acknowledged; and, ethics procedures and guideli ...
Combined action of anti-CD4 autoantibodies
... AIDS in HIV-infected patients is known to result from CD4 T lymphocyte depletion. Although a direct cytopathic effect of HIV-1 on CD4 T cells contributes to the depletion, most cells destined to die are not infected with HIV. Understanding how uninfected CD4 Т cells are eliminated is critical to the ...
... AIDS in HIV-infected patients is known to result from CD4 T lymphocyte depletion. Although a direct cytopathic effect of HIV-1 on CD4 T cells contributes to the depletion, most cells destined to die are not infected with HIV. Understanding how uninfected CD4 Т cells are eliminated is critical to the ...
Thesis_Panitz
... The diverse subsets exert different functions as professional antigen-presenting cells that produce either pro-inflammatory or immunoregulatory cytokines and interferons (IFNs) [158] and decide that way over immunity or tolerance. DCs can be roughly subdivided in classical/ myeloid DCs and plasmacyt ...
... The diverse subsets exert different functions as professional antigen-presenting cells that produce either pro-inflammatory or immunoregulatory cytokines and interferons (IFNs) [158] and decide that way over immunity or tolerance. DCs can be roughly subdivided in classical/ myeloid DCs and plasmacyt ...
Document
... (CTLs) specific for R. equi would have to derive from antigen-presenting signals (i.e., IL-12 production) in the initial stages of infection. Therefore, in immunocompetent individuals, R. equi induces a protective response that starts from the innate immune system. The effect of R. equi on dendritic ...
... (CTLs) specific for R. equi would have to derive from antigen-presenting signals (i.e., IL-12 production) in the initial stages of infection. Therefore, in immunocompetent individuals, R. equi induces a protective response that starts from the innate immune system. The effect of R. equi on dendritic ...
Biological properties of extracellular vesicles and their physiological
... the cell membrane during the differentiation of immature red blood cells (1214). More than a decade later, Raposo and colleagues demonstrated that these vesicles, then termed exosomes, isolated from EpsteinBarr virustransformed B lymphocytes, were antigen-presenting and able to induce T cell respo ...
... the cell membrane during the differentiation of immature red blood cells (1214). More than a decade later, Raposo and colleagues demonstrated that these vesicles, then termed exosomes, isolated from EpsteinBarr virustransformed B lymphocytes, were antigen-presenting and able to induce T cell respo ...
Mucosal Vaccines: Where Do We Stand?
... Mucosal immunization, especially via the intranasal and sublingual routes, also can induce substantial levels of IgA and IgG in serum [26] because mucosal DCs may migrate and carry antigen to systemic inductive sites (lymph nodes and spleen) [27,28] and a fraction of the B cells activated in the muc ...
... Mucosal immunization, especially via the intranasal and sublingual routes, also can induce substantial levels of IgA and IgG in serum [26] because mucosal DCs may migrate and carry antigen to systemic inductive sites (lymph nodes and spleen) [27,28] and a fraction of the B cells activated in the muc ...
Human CD8 CD25 thymocytes share phenotypic
... recessive disease, called IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome), is selectively ex- ...
... recessive disease, called IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome), is selectively ex- ...
13 20 s si
... system, linking innate and adaptive immune responses. However, it has been suggested a dual role of DC in Human Immunodeficiency Virus type 1 (HIV-1) infection by increasing the spread of HIV-1 while trying to trigger an adaptive response against viral infection. The classical immunological paradigm ...
... system, linking innate and adaptive immune responses. However, it has been suggested a dual role of DC in Human Immunodeficiency Virus type 1 (HIV-1) infection by increasing the spread of HIV-1 while trying to trigger an adaptive response against viral infection. The classical immunological paradigm ...
Mammary Gland Involution: Events, Regulation and
... primary research models, and the mouse serves as the archetype because of the extraordinary advances in our understanding of this species. However, comparative biology provides crucial insights into the functional intricacies of the mammary glands, and we will focus attention on various other mammal ...
... primary research models, and the mouse serves as the archetype because of the extraordinary advances in our understanding of this species. However, comparative biology provides crucial insights into the functional intricacies of the mammary glands, and we will focus attention on various other mammal ...
Immunology and Immunopathogenesis of Malaria
... thorough understanding of the mechanisms and antigens recognized at both these stages, and the differentiation of immunity to disease and infection, will be important for the construction of an effective vaccine. For each stage of the infection there are several potential targets of the protective i ...
... thorough understanding of the mechanisms and antigens recognized at both these stages, and the differentiation of immunity to disease and infection, will be important for the construction of an effective vaccine. For each stage of the infection there are several potential targets of the protective i ...
The human spleen after trauma Leemans, Rob
... B-cells (centroblasts and centrocytes), a few T-cells and follicular dendritic reticulum cells. In the lymphoid follicles a special type of dendritic cells (follicular dendritic cells) is found, which are able to bind immune complexes. They can maintain immune complexes on their cell surface for a l ...
... B-cells (centroblasts and centrocytes), a few T-cells and follicular dendritic reticulum cells. In the lymphoid follicles a special type of dendritic cells (follicular dendritic cells) is found, which are able to bind immune complexes. They can maintain immune complexes on their cell surface for a l ...
Lymphopoiesis
Lymphopoiesis (lĭm'fō-poi-ē'sĭs) (or lymphocytopoiesis) is the generation of lymphocytes, one of the five types of white blood cell (WBC). It is more formally known as lymphoid hematopoiesis.Pathosis in lymphopoiesis leads to any of various lymphoproliferative disorders, such as the lymphomas and lymphoid leukemias.