Immune responses to vaccines involving a combined antigen
... emulsion was formed by sonication (120 W; Digital Sonifier 450, Branson Ultrasonics Corp., Danbury, CT, USA) in a tube over an ice bath for 1 min (4 s on and 2 s off). To prepare the double emulsion, the resulting primary emulsion was added into 65 mL external water phase containing 1.5% w/v PVA and ...
... emulsion was formed by sonication (120 W; Digital Sonifier 450, Branson Ultrasonics Corp., Danbury, CT, USA) in a tube over an ice bath for 1 min (4 s on and 2 s off). To prepare the double emulsion, the resulting primary emulsion was added into 65 mL external water phase containing 1.5% w/v PVA and ...
Allergic disease: the diagnosis of peanut allergy and the role of heat
... group 2 innate lymphoid cells (ILC2) and dendritic cells. Activated ILC2 cells produce large quantities of IL-5 and IL-13.The activated dendritic cells present the allergen via interaction ...
... group 2 innate lymphoid cells (ILC2) and dendritic cells. Activated ILC2 cells produce large quantities of IL-5 and IL-13.The activated dendritic cells present the allergen via interaction ...
xia immune activation 1
... of susceptible regions such as aortic arches through Toll-like receptors 2/4 to promote vascular inflammation and atherosclerosis.12,13 Stressed endothelial cells also upregulate chemokines and adhesion molecules (including CCL5, CXCL1, macrophage migration inhibitory receptor, E-selectin, and vascu ...
... of susceptible regions such as aortic arches through Toll-like receptors 2/4 to promote vascular inflammation and atherosclerosis.12,13 Stressed endothelial cells also upregulate chemokines and adhesion molecules (including CCL5, CXCL1, macrophage migration inhibitory receptor, E-selectin, and vascu ...
ABSTRACT Title of Document:
... required for WASP and N-WASP activation. Inhibition of Btk activity by a point mutation or a specific inhibitor prevents BCR-induced increases in PtdIns-4,5-P2 as well as in phosphorylated WASP, N-WASP and Vav. Furthermore, Btk deficiency or inhibition leads to a severe reduction in BCR-mediated an ...
... required for WASP and N-WASP activation. Inhibition of Btk activity by a point mutation or a specific inhibitor prevents BCR-induced increases in PtdIns-4,5-P2 as well as in phosphorylated WASP, N-WASP and Vav. Furthermore, Btk deficiency or inhibition leads to a severe reduction in BCR-mediated an ...
Granulocyte Macrophage Colony-Stimulating Factor
... activated macrophages (M2-polarized) generated by exposure to interleukin 4 (IL-4)/IL-13. In addition, it is known that regulatory monocytes and macrophages that produce IL-10 or transforming growth factor-b are generated in response to glucocorticoids or interferon-g alone.8,9 Advances in our under ...
... activated macrophages (M2-polarized) generated by exposure to interleukin 4 (IL-4)/IL-13. In addition, it is known that regulatory monocytes and macrophages that produce IL-10 or transforming growth factor-b are generated in response to glucocorticoids or interferon-g alone.8,9 Advances in our under ...
IL-17/IL-17 receptor system in autoimmune disease
... Left-hand panel, naive mouse T-cells can be differentiated into three subsets of effector Th cells. Differentiation of each subset is under the control of a distinct set of cytokines. IL-12 and IL-4 promote Th1 and Th2 differentiation respectively, whereas the Th17 differentiation is under the contr ...
... Left-hand panel, naive mouse T-cells can be differentiated into three subsets of effector Th cells. Differentiation of each subset is under the control of a distinct set of cytokines. IL-12 and IL-4 promote Th1 and Th2 differentiation respectively, whereas the Th17 differentiation is under the contr ...
History of Immunology
... disease that the sick and the dying found most compassion. These knew what it was from experience, and had now no fear for themselves; for the same man was never attacked twice - never at least fatally” Resistance to re-infection-Immunity Department of Immunology ...
... disease that the sick and the dying found most compassion. These knew what it was from experience, and had now no fear for themselves; for the same man was never attacked twice - never at least fatally” Resistance to re-infection-Immunity Department of Immunology ...
Department of Cellular Biology, Physiology and Immunology Faculty of Medicine
... proteomic analysis, we have detected 161 microvesicle-associated proteins, including many related to the complement and coagulation signal-transduction cascades. However, when exosomes-enriched preparations were analysed the number of proteins identified was much reduced, suggesting that under healt ...
... proteomic analysis, we have detected 161 microvesicle-associated proteins, including many related to the complement and coagulation signal-transduction cascades. However, when exosomes-enriched preparations were analysed the number of proteins identified was much reduced, suggesting that under healt ...
the gln223arg polymorphism of the leptin receptor gene and
... distributed ubiquitously in peripheral tissues (4, 6). Leptin also plays an important role in immunity, hematopoesis, cell cycle regulation, and susceptibility to infections. It can modulate hematopoiesis by stimulating proliferation and inhibiting apoptosis of myelocytic and primitive hematopoietic ...
... distributed ubiquitously in peripheral tissues (4, 6). Leptin also plays an important role in immunity, hematopoesis, cell cycle regulation, and susceptibility to infections. It can modulate hematopoiesis by stimulating proliferation and inhibiting apoptosis of myelocytic and primitive hematopoietic ...
Curriculum Vitae - Institute of Experimental Immunology
... 3. Reinhard Obst, Christian Münz, Stefan Stevanović and Hans-Georg Rammensee, "Generation of allo- and self-restricted cytotoxic T lymphocytes against a peptide library: evidence for a functionally diverse allo-restricted T cell repertoire", European Journal of Immunology (1998), 28:2432-2443. 4. Jo ...
... 3. Reinhard Obst, Christian Münz, Stefan Stevanović and Hans-Georg Rammensee, "Generation of allo- and self-restricted cytotoxic T lymphocytes against a peptide library: evidence for a functionally diverse allo-restricted T cell repertoire", European Journal of Immunology (1998), 28:2432-2443. 4. Jo ...
Dendritic cells expand antigen-specific Foxp3+ CD25+ CD4+
... Although antigen-specific Tregs are likely to be critical in regulating immune responses to antigens in self-tissues, tumors, transplants, and infections, the literature clearly indicates that once the Treg is triggered, suppression extends to immune responses elicited by other antigens presented on ...
... Although antigen-specific Tregs are likely to be critical in regulating immune responses to antigens in self-tissues, tumors, transplants, and infections, the literature clearly indicates that once the Treg is triggered, suppression extends to immune responses elicited by other antigens presented on ...
24. Lymphatic System
... Lymphatic structures contain T-lymphocytes, B-lymphocytes, and macrophages (monocytes that have migrated from the bloodstream into other tissues). These cells are constantly monitoring the blood and the interstitial fluid for antigens (an ́ti-gen; anti(body) + gen = ...
... Lymphatic structures contain T-lymphocytes, B-lymphocytes, and macrophages (monocytes that have migrated from the bloodstream into other tissues). These cells are constantly monitoring the blood and the interstitial fluid for antigens (an ́ti-gen; anti(body) + gen = ...
PDF - Thomsen Lab
... both subunits of CBF are mutated in human leukemias. The human homolog of cbfa2 is one of the most commonly affected genes in translocations associated with acute myeloid leukemia and is therefore termed aml1 (Miyoshi et al., 1991). More recently, cbfb has also been found to be mutated in leukemias ...
... both subunits of CBF are mutated in human leukemias. The human homolog of cbfa2 is one of the most commonly affected genes in translocations associated with acute myeloid leukemia and is therefore termed aml1 (Miyoshi et al., 1991). More recently, cbfb has also been found to be mutated in leukemias ...
1 2. Endoscopic Anatomy of the Paranasal Sinuses Anatomical
... the frontonasal duct. This is normally approached from the semilunar hiatus via the ethmoidal infundibulum, but after ethmoidectomy and clearance of the infundibulum it is entered directly from the nasal cavity. Identification of the agger nasi from the nasal introitus is therefore important. The ag ...
... the frontonasal duct. This is normally approached from the semilunar hiatus via the ethmoidal infundibulum, but after ethmoidectomy and clearance of the infundibulum it is entered directly from the nasal cavity. Identification of the agger nasi from the nasal introitus is therefore important. The ag ...
Repertoire Genetic Control of Human NK Cell
... blood stem cells (n ⫽ 4) from HLA-matched sibling donors. The remaining six patients received bone marrow from unrelated donors (MUD). This group included 6 males and 12 females, with a median age of 39 years (range, 21–54 years). Pretransplant myeloablative regimens included a combination of busulf ...
... blood stem cells (n ⫽ 4) from HLA-matched sibling donors. The remaining six patients received bone marrow from unrelated donors (MUD). This group included 6 males and 12 females, with a median age of 39 years (range, 21–54 years). Pretransplant myeloablative regimens included a combination of busulf ...
Intracellular NAD+ levels are associated with LPS-induced TNF
... It is thus clear that NAD + is involved in macrophage proinflammatory responses involving TNF-α. Previous interest in the pharmacological modulation of NAD + homoeostasis has led to a number of drugs entering clinical trials as chemotherapeutic agents for cancer [10]. Given the link between NAD + an ...
... It is thus clear that NAD + is involved in macrophage proinflammatory responses involving TNF-α. Previous interest in the pharmacological modulation of NAD + homoeostasis has led to a number of drugs entering clinical trials as chemotherapeutic agents for cancer [10]. Given the link between NAD + an ...
The Equine Endometrial Cup Reaction
... observed a “whitish band nearly a quarter of an inch in width consisting of numerous delicate folds separated from each other by deep furrows, which helps to fix the horse embryo to the uterus” (Figure 1b) (2, p.16). Ewart’s chorionic girdle (Figure 2c,d), a discrete, thickened band of rapidly multi ...
... observed a “whitish band nearly a quarter of an inch in width consisting of numerous delicate folds separated from each other by deep furrows, which helps to fix the horse embryo to the uterus” (Figure 1b) (2, p.16). Ewart’s chorionic girdle (Figure 2c,d), a discrete, thickened band of rapidly multi ...
autoimmunity - Thyroid Disease Manager
... approximately equal ratios of T and B cells. B lymphocytes synthesize immunoglobulins that are first expressed on their membranes as clonally distributed antigen-specific receptors and then secreted as antibodies following antigenic stimulation. The ability of the immune system to recognize antigens ...
... approximately equal ratios of T and B cells. B lymphocytes synthesize immunoglobulins that are first expressed on their membranes as clonally distributed antigen-specific receptors and then secreted as antibodies following antigenic stimulation. The ability of the immune system to recognize antigens ...
Immune Notes 1 - Little Miami Schools
... -Antigens are unique molecules recognized by the immune system that mark cells, viruses, etc. ...
... -Antigens are unique molecules recognized by the immune system that mark cells, viruses, etc. ...
Thymus Gland - Spirit of Health
... colostrum immediately prior to giving birth to their young. Bovine colostrum has been used medicinally for thousands of years. or to and after birth. If the newborn calf does not get colostrum from its mother within the first week, it will die. Unlike in human ws, so the calf must get it all from t ...
... colostrum immediately prior to giving birth to their young. Bovine colostrum has been used medicinally for thousands of years. or to and after birth. If the newborn calf does not get colostrum from its mother within the first week, it will die. Unlike in human ws, so the calf must get it all from t ...
International Society for Biological Therapy of Cancer 24th Annual
... eliminate them through apoptosis as none histocompatible cell forms! This elimination of cancer cells is succeeded by a wellcoordinated but very complex immune-biochemical mechanism! That autologous immune response eliminate everywhere, the patient’s body, the recognized none histocompatible cancer ...
... eliminate them through apoptosis as none histocompatible cell forms! This elimination of cancer cells is succeeded by a wellcoordinated but very complex immune-biochemical mechanism! That autologous immune response eliminate everywhere, the patient’s body, the recognized none histocompatible cancer ...
Lymphopoiesis
Lymphopoiesis (lĭm'fō-poi-ē'sĭs) (or lymphocytopoiesis) is the generation of lymphocytes, one of the five types of white blood cell (WBC). It is more formally known as lymphoid hematopoiesis.Pathosis in lymphopoiesis leads to any of various lymphoproliferative disorders, such as the lymphomas and lymphoid leukemias.