Doctoral thesis from the Department of Immunology,
... the release of cytotoxic reactive oxygen intermediates (ROI) [16]. The ability of pathogenic mycobacteria to adapt to the hostile environment of macrophages has been instrumental in its success as a pathogen. Mycobacteria interfere with host trafficking pathways by modulating events in the endosoma ...
... the release of cytotoxic reactive oxygen intermediates (ROI) [16]. The ability of pathogenic mycobacteria to adapt to the hostile environment of macrophages has been instrumental in its success as a pathogen. Mycobacteria interfere with host trafficking pathways by modulating events in the endosoma ...
Full-Text PDF
... In brief prion or TSE agents are opsonized by complement components including C1q and C3, most likely via the classical complement activation pathway, which may aid in their targeting of the agent to lymphoid follicles. Mice lacking in complement components C1qa, C2 or C3 revealed deficient peripher ...
... In brief prion or TSE agents are opsonized by complement components including C1q and C3, most likely via the classical complement activation pathway, which may aid in their targeting of the agent to lymphoid follicles. Mice lacking in complement components C1qa, C2 or C3 revealed deficient peripher ...
The Spheno-Palatine Ganglion of the Albino Rat
... From the histological viewpoint, then,there seems to be a unanimity of morphological findings among the various workers, even though different staining. ...
... From the histological viewpoint, then,there seems to be a unanimity of morphological findings among the various workers, even though different staining. ...
BIOL 105 S 2011 Ch 14 Practice Midterm Exam 2 110429.1
... 44) In an experimental situation, a virus is injected into a rabbit and the rabbit is allowed to make antibodies for the viral antigen. These antibodies are then removed from the rabbit plasma and injected into a human to help deal with the same viral disease. This would be an example of A) innate i ...
... 44) In an experimental situation, a virus is injected into a rabbit and the rabbit is allowed to make antibodies for the viral antigen. These antibodies are then removed from the rabbit plasma and injected into a human to help deal with the same viral disease. This would be an example of A) innate i ...
Monocytes high Differentiation of Ly-6C from the CCR2
... We previously demonstrated that CCR2 mediates the accumulation of large numbers of DC within the lungs of mice infected with Cryptococcus neoformans (7). This encapsulated yeast, acquired by the respiratory tract, causes pneumonia and disseminated infection in immunocompromised patients (21–23) and ...
... We previously demonstrated that CCR2 mediates the accumulation of large numbers of DC within the lungs of mice infected with Cryptococcus neoformans (7). This encapsulated yeast, acquired by the respiratory tract, causes pneumonia and disseminated infection in immunocompromised patients (21–23) and ...
Analysis of the roles of Interleukin 15 and CD4+ T cells specific of a
... availability in spite of your tight schedule, for all regular meetings and discussions that we had. Thank you for having given me a large autonomy and your precious advice at moments when I particularly needed it. Thanks for the time you devoted for improving of our manuscripts and correction of thi ...
... availability in spite of your tight schedule, for all regular meetings and discussions that we had. Thank you for having given me a large autonomy and your precious advice at moments when I particularly needed it. Thanks for the time you devoted for improving of our manuscripts and correction of thi ...
surgical anatomy for endoscopic sphenoethmoidectomy
... anterior and posterior ethmoid cells. ◦ Pneumatization of the suprabullar recess: insertion of basal lamella to skull base superiorly is located posterior to nferior part of oblique segment ◦ Pneumatization of retrobullar recess: inferior part of basal lamella assumes a more posterior position a ...
... anterior and posterior ethmoid cells. ◦ Pneumatization of the suprabullar recess: insertion of basal lamella to skull base superiorly is located posterior to nferior part of oblique segment ◦ Pneumatization of retrobullar recess: inferior part of basal lamella assumes a more posterior position a ...
Colon Carcinoma Model to Cure Established Tumors in a Murine
... oligodeoxynucleotides (CpG ODN) that mimic bacterial DNA (9). CpG ODN represent a major improvement over bacterial DNA, since they are well-defined molecules that can be protected chemically against degradation by nucleases and synthesized in large quantities. CpG ODN are potent vaccine adjuvants wi ...
... oligodeoxynucleotides (CpG ODN) that mimic bacterial DNA (9). CpG ODN represent a major improvement over bacterial DNA, since they are well-defined molecules that can be protected chemically against degradation by nucleases and synthesized in large quantities. CpG ODN are potent vaccine adjuvants wi ...
Lectins, Mitogens and Agglutinins
... Cells require attachment to a substrate to grow; when denied anchorage or when attachment is prevented, they undergo a particular type of apoptosis known as ‘anoikia.’ Strategies aimed at blocking the effects. ...
... Cells require attachment to a substrate to grow; when denied anchorage or when attachment is prevented, they undergo a particular type of apoptosis known as ‘anoikia.’ Strategies aimed at blocking the effects. ...
ABSTRACT Title of Document: INTERFERON
... Leishmania are intracellular parasites that reside inside macrophages and induce weak innate immune responses. We hypothesize that transgenic parasites that express immune response genes could modify the nature of the host response to the parasite. We previously generated transgenic parasites that p ...
... Leishmania are intracellular parasites that reside inside macrophages and induce weak innate immune responses. We hypothesize that transgenic parasites that express immune response genes could modify the nature of the host response to the parasite. We previously generated transgenic parasites that p ...
Th1/Th2 Balance - Alternative Medicine Review
... They suggested these “Th1” and “Th2” cells were “important regulators of the class of immune response.” The concept subsequently was applied to human immunity,2 and 10 years after the original discovery the effects of Th1 and Th2 in disease became a major research focus.3,4 Currently much of the lit ...
... They suggested these “Th1” and “Th2” cells were “important regulators of the class of immune response.” The concept subsequently was applied to human immunity,2 and 10 years after the original discovery the effects of Th1 and Th2 in disease became a major research focus.3,4 Currently much of the lit ...
Immunity against Mucosal Pathogens?
... Downloaded from http://www.jimmunol.org/ by guest on June 14, 2017 ...
... Downloaded from http://www.jimmunol.org/ by guest on June 14, 2017 ...
SERIES "RECENT DEVELOPMENTS IN PULMONARY INFECTIONS" Number 5 in this Series
... by CD4z cytotoxic T cells does not reduce the viability of the contained bacteria [54]. Progression of tuberculosis in mice deficient in perforin is not different from progression in the wild-type [55, 56]. The major role of murine CD8z cells at this stage may be the secretion of IFNc [57, 58]. Rece ...
... by CD4z cytotoxic T cells does not reduce the viability of the contained bacteria [54]. Progression of tuberculosis in mice deficient in perforin is not different from progression in the wild-type [55, 56]. The major role of murine CD8z cells at this stage may be the secretion of IFNc [57, 58]. Rece ...
The Inflammatory Response Initiated by the Spleen to Ischemic Stroke
... individuals and individuals with hyperglycemia have an increased risk of ICH with thrombolytic therapy (Martini and Kent 2007). ...
... individuals and individuals with hyperglycemia have an increased risk of ICH with thrombolytic therapy (Martini and Kent 2007). ...
Crosstalk between cancer and immune cells: role of
... cancers. Furthermore, many tumour-produced factors, such as IL-10, IL-6 and VEGF, which are crucial for both tumour growth and immunosuppression, activate STAT3 to create an efficient ‘feedforward’ mechanism to ensure increased STAT3 activity both in tumour cells and in tumour-associated immune cell ...
... cancers. Furthermore, many tumour-produced factors, such as IL-10, IL-6 and VEGF, which are crucial for both tumour growth and immunosuppression, activate STAT3 to create an efficient ‘feedforward’ mechanism to ensure increased STAT3 activity both in tumour cells and in tumour-associated immune cell ...
Basophils, IgE, and Autoantibody-Mediated Kidney
... allows basophils to contribute to Th2 immune responses is their transient mobilization into secondary lymphoid tissues. Basophils within draining lymph nodes are observed in many in vivo immune responses: immunization with protease Ags, such as papain (29) and house dust mite Ags (48), and infection ...
... allows basophils to contribute to Th2 immune responses is their transient mobilization into secondary lymphoid tissues. Basophils within draining lymph nodes are observed in many in vivo immune responses: immunization with protease Ags, such as papain (29) and house dust mite Ags (48), and infection ...
THE LYMPHATIC SYSTEM AND LYMPHOID TISSUE
... was required. In many women with early-stage breast cancer, however, the axillary bodies do not contain cancerous cells. In addition, about 20 percent of the women whose lymphatic ...
... was required. In many women with early-stage breast cancer, however, the axillary bodies do not contain cancerous cells. In addition, about 20 percent of the women whose lymphatic ...
Immunology - Department of Pathology
... All those who undertake a Research Project will have the opportunity to present their work at a day of Project Presentations starting at 10:00 am on Thursday 4 May 2017 in the Seminar Room. Details will be emailed to students closer to the date. In preparation for the “practical exam” on data handli ...
... All those who undertake a Research Project will have the opportunity to present their work at a day of Project Presentations starting at 10:00 am on Thursday 4 May 2017 in the Seminar Room. Details will be emailed to students closer to the date. In preparation for the “practical exam” on data handli ...
Macrophages and Dendritic Cells Entry Is Required for the Function
... of the CRAC channel (2–4). Opening of ORAI1 results in storeoperated Ca2+ entry (SOCE), thus called because this form of Ca2+ influx is regulated by the ER Ca2+ concentrations (5). SOCE has been demonstrated not only in T cells but also in many other types of immune cells, including B cells, mast ce ...
... of the CRAC channel (2–4). Opening of ORAI1 results in storeoperated Ca2+ entry (SOCE), thus called because this form of Ca2+ influx is regulated by the ER Ca2+ concentrations (5). SOCE has been demonstrated not only in T cells but also in many other types of immune cells, including B cells, mast ce ...
Establishment of immunohistochemical double staining
... The cells of the immune system are divided in cells involved in the innate immune response and cells of the acquired immune response, with some overlap. The acquired immune system consists of cells i ...
... The cells of the immune system are divided in cells involved in the innate immune response and cells of the acquired immune response, with some overlap. The acquired immune system consists of cells i ...
Candida albicans morphogenesis and host defence
... How the immune system interacts with the various morphogenetic forms of fungi is relatively poorly understood. In the case of C. albicans, one intriguing possibility is that differential recognition of yeast and hypha could be the key to understanding the mechanisms through which different immune re ...
... How the immune system interacts with the various morphogenetic forms of fungi is relatively poorly understood. In the case of C. albicans, one intriguing possibility is that differential recognition of yeast and hypha could be the key to understanding the mechanisms through which different immune re ...
Lymphopoiesis
Lymphopoiesis (lĭm'fō-poi-ē'sĭs) (or lymphocytopoiesis) is the generation of lymphocytes, one of the five types of white blood cell (WBC). It is more formally known as lymphoid hematopoiesis.Pathosis in lymphopoiesis leads to any of various lymphoproliferative disorders, such as the lymphomas and lymphoid leukemias.