Mycobacterium avium infections in children Johanna Thegerström
... lipoarabinomannans (LAM); in the case of M. avium: ManLAM) have been tested for their immunomodulatory properties with divergent results (Schorey JS and Sweet L 2008). Several studies have observed pro-inflammatory responses in human macrophages induced by GPLs, but responses seem to be dependent on ...
... lipoarabinomannans (LAM); in the case of M. avium: ManLAM) have been tested for their immunomodulatory properties with divergent results (Schorey JS and Sweet L 2008). Several studies have observed pro-inflammatory responses in human macrophages induced by GPLs, but responses seem to be dependent on ...
Ecology of Candida-associated Denture Stomatitis
... studies of bacteria and yeasts showed that the bacterial counts of 1-week-old denture plaque in stomatitis patients were about 10 times higher than those observed in denture wearers with healthy oral mucosa (14)). Furthermore, the corresponding yeast counts were about 100 times higher in stomatitis ...
... studies of bacteria and yeasts showed that the bacterial counts of 1-week-old denture plaque in stomatitis patients were about 10 times higher than those observed in denture wearers with healthy oral mucosa (14)). Furthermore, the corresponding yeast counts were about 100 times higher in stomatitis ...
Chronic Beryllium Disease
... beryllium sensitization” and are encouraged to undergo further medical testing to determine if they have chronic beryllium disease (CBD). Individuals with other combinations of non-normal test results, such as an abnormal and a borderline BeLPT or three borderline results, are also considered sensit ...
... beryllium sensitization” and are encouraged to undergo further medical testing to determine if they have chronic beryllium disease (CBD). Individuals with other combinations of non-normal test results, such as an abnormal and a borderline BeLPT or three borderline results, are also considered sensit ...
WJG-23-2870 - F6 Publishing Home
... physical barriers, H. pylori can transiently enter the intracellular space for a short time to reduce exposure duration to antibiotics, acidic conditions and the immune response[37]. Moreover, as H. pylori is optimally evolved to reduce its exposure to acidic gastric conditions, it can localize in m ...
... physical barriers, H. pylori can transiently enter the intracellular space for a short time to reduce exposure duration to antibiotics, acidic conditions and the immune response[37]. Moreover, as H. pylori is optimally evolved to reduce its exposure to acidic gastric conditions, it can localize in m ...
Sympathetic ophthalmia: to the twenty
... chemokines monocyte chemotactic protein-1 (CCL2/ MCP-1) and stromal cell-derived factor-1 (CXCL12/ SDF-1) within cells in granulomas of sympathetic ophthalmia [42]. Matrix metalloproteinases (MMPs), particularly gelatinase B (MMP-9), play an integral role in leukocyte migration and have been implica ...
... chemokines monocyte chemotactic protein-1 (CCL2/ MCP-1) and stromal cell-derived factor-1 (CXCL12/ SDF-1) within cells in granulomas of sympathetic ophthalmia [42]. Matrix metalloproteinases (MMPs), particularly gelatinase B (MMP-9), play an integral role in leukocyte migration and have been implica ...
Biological Functions of Haptoglobin - New Pieces to an
... association, while others provide contradictory results. For the time being, such inconclusive reports indicate that the haptoglobin phenotype has little if any practical use in clinical science. Some Biological Activities Recent data suggest that haptoglobin may have temporary but specific physiolo ...
... association, while others provide contradictory results. For the time being, such inconclusive reports indicate that the haptoglobin phenotype has little if any practical use in clinical science. Some Biological Activities Recent data suggest that haptoglobin may have temporary but specific physiolo ...
The Role of Macrophages in the Placenta
... 3. Macrophage phenotypes overview Human monocytes and macrophages are players in the innate immune system. Macrophages are bone marrow/hematopoietic-derived cells that migrate through the blood circulation to home to and take up residence within various tissues, where they play a pivotal role in coo ...
... 3. Macrophage phenotypes overview Human monocytes and macrophages are players in the innate immune system. Macrophages are bone marrow/hematopoietic-derived cells that migrate through the blood circulation to home to and take up residence within various tissues, where they play a pivotal role in coo ...
Aloe Vera and Shoe Insoles - Mission Venture Ministries
... In discussing the components of Aloe Vera, Acemannan deserves a special mention because of the very important role it plays. It stimulates the body’s macrophages to produce Interferon and Interleukin, which stop viruses multiplying. Macrophages are the deep cleansers of the immune system that can de ...
... In discussing the components of Aloe Vera, Acemannan deserves a special mention because of the very important role it plays. It stimulates the body’s macrophages to produce Interferon and Interleukin, which stop viruses multiplying. Macrophages are the deep cleansers of the immune system that can de ...
BCG plus Interferon-alpha for Superficial Bladder Cancer
... encouraging. IFN-β, closely related to IFN-α , protects against infection by a related mycobacterial pathogen MAI. BCG plus IFN-α or BCG plus the interferon inducer bropiramine are more effective than either agent alone in the murine MBT-2 and MB-49 bladder cancer models. Several pilot clinical stud ...
... encouraging. IFN-β, closely related to IFN-α , protects against infection by a related mycobacterial pathogen MAI. BCG plus IFN-α or BCG plus the interferon inducer bropiramine are more effective than either agent alone in the murine MBT-2 and MB-49 bladder cancer models. Several pilot clinical stud ...
Factors Affecting Wound Healing
... impaired wound healing, while others have reported that CD 4+ cells (T-helper cells) have a positive role in wound healing and CD8+ cells (T-suppressor-cytotoxic cells) play an inhibitory role in wound healing (Swift et al., 2001; Park and Barbul, 2004). Interestingly, recent studies in mice deficie ...
... impaired wound healing, while others have reported that CD 4+ cells (T-helper cells) have a positive role in wound healing and CD8+ cells (T-suppressor-cytotoxic cells) play an inhibitory role in wound healing (Swift et al., 2001; Park and Barbul, 2004). Interestingly, recent studies in mice deficie ...
Human papillomavirus infections in early childhood
... Human papillomaviruses (HPV) are small DNA viruses that infect epithelial cells of the skin or mucosal sites and cause epithelial lesions varying from common warts, condylomas and papillomas to invasive cancer. HPV is generally accepted as the most important independent risk factor for ...
... Human papillomaviruses (HPV) are small DNA viruses that infect epithelial cells of the skin or mucosal sites and cause epithelial lesions varying from common warts, condylomas and papillomas to invasive cancer. HPV is generally accepted as the most important independent risk factor for ...
Psoriasis - Wikipedia, the free encyclopedia
... The cause of psoriasis is not fully understood. There are two main hypotheses about the process that occurs in the development of the disease. The first considers psoriasis as primarily a disorder of excessive growth and reproduction of skin cells. The problem is simply seen as a fault of the epider ...
... The cause of psoriasis is not fully understood. There are two main hypotheses about the process that occurs in the development of the disease. The first considers psoriasis as primarily a disorder of excessive growth and reproduction of skin cells. The problem is simply seen as a fault of the epider ...
nature`s everyday - Standard Process
... independent analytical laboratory accredited by the Australian Therapeutic Goods Administration. 2-ene are only found in Echinacea angustifolia and are an important measure of quality. MediHerb’s research has found that 2-ene alkylamides improve the bioavailability of 2,4-diene alkylamides in Echina ...
... independent analytical laboratory accredited by the Australian Therapeutic Goods Administration. 2-ene are only found in Echinacea angustifolia and are an important measure of quality. MediHerb’s research has found that 2-ene alkylamides improve the bioavailability of 2,4-diene alkylamides in Echina ...
Hepatitis B vaccination: a completed schedule...enough to control
... This meeting provided the opportunity to review long-term immunogenicity and efficacy of a complete course of hepatitis B (HepB) vaccine and field effectiveness of the implemented HepB immunization programmes. Recent data on immune memory induced by HepB vaccine and on the anamnestic response after ...
... This meeting provided the opportunity to review long-term immunogenicity and efficacy of a complete course of hepatitis B (HepB) vaccine and field effectiveness of the implemented HepB immunization programmes. Recent data on immune memory induced by HepB vaccine and on the anamnestic response after ...
Evaluation of Immune Responses to Novel Adeno-Associated Viruses
... successfully in the past using existing Adeno-associated viruses (AAVs). Also, it has recently been shown that AAV can stimulate robust antibody responses due to long-term transgene expression or abolishment of transgene product by cell-mediated immune responses, suggesting the potential use of AAVs ...
... successfully in the past using existing Adeno-associated viruses (AAVs). Also, it has recently been shown that AAV can stimulate robust antibody responses due to long-term transgene expression or abolishment of transgene product by cell-mediated immune responses, suggesting the potential use of AAVs ...
UNIVERSIDAD DE MURCIA FACULTAD DE BIOLOGÍA
... IL-1 is a major mediator of inflammation and in general initiates and/or increases a wide variety of non-structural function-associated genes that are characteristically expressed during inflammation, particularly other cytokines. It is one of the key mediators of the body’s response to microbial in ...
... IL-1 is a major mediator of inflammation and in general initiates and/or increases a wide variety of non-structural function-associated genes that are characteristically expressed during inflammation, particularly other cytokines. It is one of the key mediators of the body’s response to microbial in ...
Design of Noninflammatory Synthetic siRNA Mediating Potent Gene
... As part of the innate defense mechanism against invading pathogens, the mammalian immune system is activated by a number of exogenous RNA [10–12] and DNA species [13], resulting in the release of inflammatory cytokines and interferons (IFN) such as IFN-a. Initial studies on the off-target effects of ...
... As part of the innate defense mechanism against invading pathogens, the mammalian immune system is activated by a number of exogenous RNA [10–12] and DNA species [13], resulting in the release of inflammatory cytokines and interferons (IFN) such as IFN-a. Initial studies on the off-target effects of ...
Micro Chapter 13 [4-20
... If not, innate immunity still can opsonize it, especially by complement that bind to the bacteria when there’s no antibodies, to opsonize o Complement binding is more efficient against some strains than others, make some more or less virulent Also, C reactive protein (CRP) reacts with phosphoryl ...
... If not, innate immunity still can opsonize it, especially by complement that bind to the bacteria when there’s no antibodies, to opsonize o Complement binding is more efficient against some strains than others, make some more or less virulent Also, C reactive protein (CRP) reacts with phosphoryl ...
Detectable levels of interleukin-18 in uterine luminal secretions at
... from inadequate uterine receptivity. There is currently no way to predict this receptivity. METHODS: We investigated whether the detection of interleukin-(IL)18 by ELISA in uterine luminal secretions might predict implantation failure. Secretions of 133 patients enrolled in our IVF-ET program were s ...
... from inadequate uterine receptivity. There is currently no way to predict this receptivity. METHODS: We investigated whether the detection of interleukin-(IL)18 by ELISA in uterine luminal secretions might predict implantation failure. Secretions of 133 patients enrolled in our IVF-ET program were s ...
Critical care Immunology
... the mediators (cytokines) responsible for cellular and clinical changes during the inflammatory response. Correlate the clinical significance of immunoparalysis to trauma, sepsis and open heart surgery. Evaluate strategies used to manage patients with immunoparalysis. [email protected] ...
... the mediators (cytokines) responsible for cellular and clinical changes during the inflammatory response. Correlate the clinical significance of immunoparalysis to trauma, sepsis and open heart surgery. Evaluate strategies used to manage patients with immunoparalysis. [email protected] ...
Cancer immunotherapy
Cancer immunotherapy (immuno-oncology) is the use of the immune system to treat cancer. Immunotherapies fall into three main groups: cellular, antibody and cytokine. They exploit the fact that cancer cells often have subtly different molecules on their surface that can be detected by the immune system. These molecules, known as cancer antigens, are most commonly proteins, but also include molecules such as carbohydrates. Immunotherapy is used to provoke the immune system into attacking the tumor cells by using these antigens as targets.Antibody therapies are the most successful immunotherapy, treating a wide range of cancers. Antibodies are proteins produced by the immune system that bind to a target antigen on the cell surface. In normal physiology the immune system uses them to fight pathogens. Each antibody is specific to one or a few proteins. Those that bind to cancer antigens are used to treat cancer. Cell surface receptors are common targets for antibody therapies and include the CD20, CD274, and CD279. Once bound to a cancer antigen, antibodies can induce antibody-dependent cell-mediated cytotoxicity, activate the complement system, or prevent a receptor from interacting with its ligand, all of which can lead to cell death. Multiple antibodies are approved to treat cancer, including Alemtuzumab, Ipilimumab, Nivolumab, Ofatumumab, and Rituximab.Cellular therapies, also known as cancer vaccines, usually involve the removal of immune cells from the blood or from a tumor. Immune cells specific for the tumor are activated, cultured and returned to the patient where the immune cells attack the cancer. Cell types that can be used in this way are natural killer cells, lymphokine-activated killer cells, cytotoxic T cells and dendritic cells. The only cell-based therapy approved in the US is Dendreon's Provenge, for the treatment of prostate cancer.Interleukin-2 and interferon-α are examples of cytokines, proteins that regulate and coordinate the behaviour of the immune system. They have the ability to enhance anti-tumor activity and thus can be used as cancer treatments. Interferon-α is used in the treatment of hairy-cell leukaemia, AIDS-related Kaposi's sarcoma, follicular lymphoma, chronic myeloid leukaemia and malignant melanoma. Interleukin-2 is used in the treatment of malignant melanoma and renal cell carcinoma.