UNIVERSIDAD DE MURCIA FACULTAD DE BIOLOGÍA
... (Nakae et al., 2001). Both IL-1α and IL-1β are produced by many different cell types
(Oppenheim et al., 1986), including neutrophils, natural killer cells, B-lymphocytes, Tlymphocytes and cells of the central nervous system. However the main producing cells
are blood monocytes and tissue macrophages ...