Download Immunity Student Outline

AP Biology Organism Form and Function
Unit 5: Immunology Outline
J. Miller
Learning Objectives:
2.28 The student is able to use representations or models to analyze quantitatively and
qualitatively the effects of disruptions to dynamic homeostasis in biological systems.
2.29 The student can create representations and models to describe immune responses.
2.30 The students can create representations or models to describe nonspecific immune defenses
in plants and animals.
3.34 The student is able to construct explanations of cell communication through cell-to-cell
direct contact or through chemical signaling.
3.35 The student is able to create representation(s) that depict how cell-to-cell communication
occurs by direct contact or from a distance through chemical signaling.
Lecture Outline:
I.
II.
III.
Overview and Historical Background to Immunology
A. Pathogen
B. Smallpox inoculations
C. Jenner and cowpox
D. Pasteur
Innate Immunity (non-specific)
A. Barriers to invasion
B. Phagocytes
C. Complement System
D. Inflammation
E. Interferons
Adaptive or Acquired Immunity (specific
A. General
B. Cells:
1. Macrophages
2. Helper T cells
3. B cells
4. Killer T cells
5. Suppressor T cells
6. Memory cells
C. Weapons
1. Antibodies
2. Lymphokines and interleukins
3. Perforin
IV.
V.
VI.
VII.
VIII.
IX.
X.
XI.
XII.
Recognition of Self and Non-Self
A. Major Histocompatibility Complex (MHC) and MHC markers
B. Antigens
Primary Immune Response
A. Antibody mediated immune response (humoral)
1. Role of B cells
2. Specificity
3. Virgin B cells
4. MHC markers
5. Helper T cells
6. Lymphokines
7. B cell clones
B. Plasma cells
C. Immunoglobulins (Ig)
Cell Mediated Immune Response
A. T cells and the thymus
B. Killer T cells
Control of Immune Responses
Antibody Diversity and Clonal Selection Theory
Secondary Immune Response
Immunization
Allergies
Auto-immune disorders
XIII.
Deficient Immune Response: AIDS And HIV Virus
XIV.
HIV Replication cycle
XV.
XVI.
XVII.
Modes of Transmission of AIDS
HIV Drugs
Hybridoma Technology