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Transcript
Other Players in the IMMUNE RESPONSE Specialized Cells are Circulated via the Lymphatic System ANTIGEN-ANTIBODY • Antibody—Protein known as an immunoglobin. Produced by the B cells. An effector of the immune response. • Antigen—ANTIbody GENerator. A foreign macromolecule that elicits an immune response. • The specificity between the shapes of antigens and antibodies are the basis of the immune response. Chemical Signals • Chemokines—Molecules secreted by epithelial cells & monocytes to attract phagocytes to an area. • Complement System—20 serum proteins that act to lyse microbes. • Interferon—Protein secreted by virus invaded cells to warn neighboring cells. Chemical Signals • Major Histocompatibility Complex (MHC)Glycoprotein molecules that mark cells as “self”. • Most polymorphic genes known—we all have unique combinations of MHC molecules. • Cytotoxic T cells bind to MHC I molecules • Helper T cells bind to MHC II molecules