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Honors Biology – Chapter 11 and 14 Genetics: Learning Objectives Name Date 1. Demonstrate an ability to meet deadlines by turning in assignments on time. 2. Demonstrate an ability to use appropriate grammar and spelling and to make corrections as necessary. Essential Question A. How is DNA organized in cells, and why is this important? 3. How DNA is stored as chromosomes (including how DNA, histones, nucleosomes interact) 4. Explain how most cells contains two copies of each chromosome Essential Question B. How does DNA get distributed as organisms create reproductive cells (e.g. sperm and egg), and how is DNA combined when these cells join during fertilization? 5. Describe and model the process of meiosis in which reproductive cells (e.g., egg, sperm) are formed with only one set of chromosomes from each parent. 6. Explain what occurs during all steps of meiosis I and II 7. Compare and contrast meiosis and mitosis 8. Model and explain the process of genetic recombination that may occur during meiosis and how this then results in differing characteristics in offspring (e.g., differences in how chromosomes “line up” during Metaphase I, crossing over of chromosome tips) 9. Describe the process of fertilization that restores the original chromosome number while reshuffling the genetic information, allowing for variation among offspring. Essential Question C. What happens if mistakes or problems occur during meiosis and/or fertilization? 10. Explain how “mistakes” in the copying of genetic material can be inherited by future generations (mutations). 11. Explain how these mistakes can occur in meiosis Essential Question D. How does DNA that is combined during fertilization interact? In other words, how does an organism inherit its traits, and how do chromosomes from two different parents work together to create your traits? 12. Predict the outcome of genetic crosses involving two characteristics assuming independent assortment) 13. Explain the principle of dominance (one gene with a dominant and recessive allele) 14. Explain other inheritance patterns, including incomplete dominance, codominance, multiple alleles and polygenic traits 15. Set up and complete Punnett squares for how one or two traits could be inherited and expressed, including traits that follow the principle of dominance as well as those show incomplete dominance and codominance 16. Explain the following terms: genotype, phenotype, trait, hybrid, gene, allele, segregation, gamete, F1 generation, F2 generation, homozygous, heterozygous, haploid, diploid, homologous, autosomal chromosome and sex chromosome 17. Explain gene linkage, independent assortment, crossing over, and generally explain how the inheritance of traits is affected by the location of genes on chromosomes 18. Explain how a karyotype is arranged and how karyotypes can be used to show the presence of chromosomal mutations; explain how “nondisjunction” can occur 19. Construct and interpret pedigrees using information about dominant/recessive traits passed down through families 20. Explain the term and predict outcomes of crosses involving “sex-linked traits”.