Download A Test to Assess the Auditory Brainstem Response to Speech

A Test to Assess the Auditory
Brainstem Response to Speech
Approximately 5% to 10% of children are diagnosed with learni
products, is a neurophysiological test used to quickly & objectiv
Developed at Northwestern University,
BioMARK is an electrophysiologic
response from the brainstem that
mimics the characteristics of speech with
remarkable fidelity.
Why BioMARK?
• Studies at the Northwestern University Auditory Neuroscience Laboratory on children from 8-12 years of age have
shown that the BioMARK response is abnormal in approximately 30% of children who have been diagnosed with various learning problems1
• Children with learning problems who have abnormal BioMARK responses will benefit most from auditory training programs
• BioMARK is an objective test, requiring no behavioral response
LD
BioMARK responses have been studied on normal hearing children from
ADHD
AUDITORY
PERCEPTION &
NEURAL
ENCODING
DEFICITS
SLI
Dyslexia
8-12 years of age who have various diagnoses that may include auditorybased learning problems, such as dyslexia, central auditory processing
disorders (CAPD), specific language impairment (SLI), learning disability
CAPD
(LD), and attention deficit hyperactivity disorder (ADHD).
Who is a candidate for the BioMARK test?
Normative data for the BioMARK response is available for normal hearing children between 8-12 years of age. The child
must be capable of sitting relatively quietly for approximately 30 minutes.
How is the BioMARK test performed?
• Child should be awake, but comfortable & quiet for 20-30 minutes
(i.e. watching video)
• Electrodes are placed on the head using a standard, 1-channel ABR montage
• An insert earphone is placed in the right ear for delivery of the acoustic stimulus
• Click evoked ABR is performed first to confirm normal standard ABR
BioMARK responses
• Two trials of 3000 averages are performed, added together & responses averaged
• Wave V and A are marked by user with normative wave template as guide
• Computer-assisted measures of latency, slope & spectral amplitude along with overall BioMARK score are
calculated & displayed for review
• Standard BioMARK report templates are available for printing results
B i o - l o g i c
ing disabilities. BioMARK (Biological Marker of Auditory Processing), part of the Navigator PRO family of diagnostic
vely identify disordered processing of sound that has been associated with learning impairments in many children.
Elements of the speech stimulus
corresponding to peaks in the
BioMARK response
~ 120 Hz
~ 120 Hz
BioMARK score & response measures
display for easy analysis
0
1
2
~ 120 Hz
~ 120 Hz
3
Time (ms)
4
5
6
Graphic courtesy of Auditory Neuroscience Laboratory, Northwestern University. Nina Kraus, Director.
If the child’s BioMARK response is abnormal, what is the next step?
The child may be a good candidate for auditory-based intervention training. Research at Northwestern University Auditory
Neuroscience Laboratory has shown that some children who have disordered neural responses to sound (reflected by
BioMARK) may benefit from commercially available computer-based auditory training programs.1
If BioMARK results are normal, but other types of behavioral tests suggest that the child has auditorybased learning problems, what is the next course of action?
Studies at Northwestern University showed that 70% of children with diagnosed learning problems had normal BioMAP
responses. No single test, including BioMARK, assesses all of a child’s abilities. Because BioMARK is only one test, other
types of evaluations, such as a psychoeducational assessment, which may be available through the child's school or a
private practitioner, should be considered.
Future Developments
• Studies are currently underway at Northwestern University to assess the BioMARK response on normally developing
children from 3-5 years of age
• Test potential may be even greater if the BioMARK response can identify young children at-risk for auditory-based learning problems before their formal education begins
For more information on the research behind BioMARK, visit the website of Northwestern University Auditory
Neuroscience Laboratory at www.communication.northwestern.edu/brainvolts/clinicaltechnologies/.
1References on file.
*BioMARK was developed by Nina Kraus, Trent Nicol, Erika Skoe and Steven Zecker at Northwestern University Auditory Neuroscience Laboratory, Evanston, IL.
B i o - l o g i c
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Standard auditory evoked
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Biological Marker
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Your Local Bio-logic Representative:
*
Developed in cooperation with Sasha John, Ph.D. and Terence W. Picton M.D., Ph.D. at Rotman Research Institute
of Baycrest Centre, Toronto, Ontario, Canada. Patent Number: 6602202.
**
Developed in cooperation with Manuel Don, Ph.D. at House Ear Institute. Patent Numbers: 6080112 and 6264616B1.
*** Developed in cooperation with Manuel Don, Ph.D. at House Ear Institute. Patent applied for.
**** Developed in cooperation with Nina Kraus, Ph.D. and Trent Nicol at Northwestern University Auditory Neuroscience Laboratory.
*****Developed in cooperation with Sigfrid Soli, Ph.D. at House Ear Institute.
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