Download Slide ()

The eukaryotic nuclear genetic code. A, The RNA codons appear in boldface type; the complementary DNA codons are in italics. A = adenine; C =
cytosine; G = guanine; T = thymine; U = uridine (replaces thymine in RNA). In RNA, adenine is complementary to thymine of DNA; uridine is
complementary to adenine of DNA; cytosine is complementary to guanine and vice versa. “Stop” = peptide chain termination. The three-letter and singleletter abbreviations for the amino acids are as follows: Ala (A) = alanine; Arg (R) = arginine; Asn (N) = asparagine; Asp (D) = aspartic acid; Cys (C) =
cysteine; Gln (Q) = glutamine; Glu (E) = glutamic acid; Gly (G) = glycine; His (H) = histidine; Ile (I) = isoleucine; Leu (L) = leucine; Lys (K) = lysine; Met (M)
= methionine; Phe (F) = phenylalanine; Pro (P) = proline; Ser (S) = serine; Thr (T) = threonine; Trp (W) = tryptophan; Tyr (Y) = tyrosine; Val (V) = valine. B,
Source: Genetics, Biochemistry, and Molecular Bases of Variant Human Phenotypes, The Online Metabolic and Molecular Bases of Inherited
The outermost complete circle represents the amino acid in single letter code or a stop codon (*); the DNA sense strand for the triplet codon for each
Disease
amino acid is given on the radial, starting with the first base of the codon in the center. Differences in the mitochondrial genetic code are shown in the
Citation: Valle D, Beaudet AL, Vogelstein B, Kinzler KW, Antonarakis SE, Ballabio A, Gibson K, Mitchell G. The Online Metabolic and Molecular
outermost boxes.
Bases of Inherited Disease; 2014 Available at: http://mhmedical.com/ Accessed: May 05, 2017
Copyright © 2017 McGraw-Hill Education. All rights reserved