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Form: IKMP-SIF IN SILICO KINASE MATCH PREDICTION SERVICE IDENTIFICATION FORM NAME: KINEXUS ORDER NUMBER COMPANY/INSTITUTE: (Authorized Representative or Principal Investigator) STANDARD IN SILICO PROTEIN KINASE MATCH PREDICTION SERVICES REQUESTED: Use this form to order one or more of the three Standard In Silico Protein Kinase Match Prediction (IKMP) Services currently offered by Kinexus. Please check the appropriate tick boxes. If you need assistance, please contact a technical service representative by calling toll free in North America 1-866-KINEXUS (866546-3987) or by email at [email protected]. A. CLIENT SCREEN ID NAME: STANDARD SERVICES REQUESTED: IKMP KINEXUS ID NUMBER Prediction Services with Kinexus’ proprietary algorithms and databases to permit identification of protein kinase – phospho-site (P-site) interactions A human protein kinase name or P-site peptide amino acid (AA) sequence provided by the client is required (Bar Code Identification Number) Customer ID: Provide ID name of your choice for this order for your own reference For Kinexus Internal Use Only. B. IKMP SCREEN SELECTION: Use one of the two options shown below for this sheet. Complete a second IKMP-SIF sheet for also using the other option or if additional analyses are required. Consult the IKMP Customer Information Package for more details. Option 1 - IKMP-PK Service – Identification of up to 100 top scoring human protein kinases that target the same 15 AA P-site sequence Note that the P-site amino acid must appear in position 0. Use “X” to denote a space if the P-site originates from the Nor C-terminus of a protein (e.g. if the phospho-acceptor AA Serine is in the second AA residue position of the substrate protein after a Methionine, then the sequence would begin “XXXXXXMS”). -7 -6 -5 -4 -3 –2 –1 0 +1 +2 +3 +4 +5+6 +7 Client Name for Peptide C. PRICING: IKMP-PK for 1 analysis (1 P-site) = $ 89 IKMP-PS-1K for 1 analysis (1 kinase) = $ 89 IKMP-PS-5K for 1 analysis (1 kinase) = $ 179 Use this pricing information for completion and submission of Service Order Form IKMP-SOF. Phosphopeptide 1 Phosphopeptide 2 D. AMINO ACID REFERENCE CODES Phosphopeptide 3 Phosphopeptide 4 Phosphopeptide 5 Phosphopeptide 6 Phosphopeptide 7 Phosphopeptide 8 Option 2A or Option 2B - IKMP-PS-1K Service – Identification of 1000 top predicted human phospho-sites for a target human protein kinase. - IKMP-PS-5K Service – Identification of 5000 top predicted human phospho-sites for a target human protein kinase. Short Name for Kinase Uniprot ID Number Protein Kinase 1 Protein Kinase 2 Protein Kinase 3 Protein Kinase 4 Protein Kinase 5 Protein Kinase 6 Protein Kinase 7 Protein Kinase 8 A C D E F G H I K L M N P Q R S T V W Y - Ala - Alanine Cys - Cysteine Asp - Aspartic acid Glu - Glutamic acid Phe - Phenylalanine Gly - Glycine His - Histidine Ile - Isoleucine Lys - Lysine Leu - Leucine Met - Methionine Asn - Asparagine Pro - Proline Gln - Glutamine Arg - Arginine Ser - Serine Thr - Threonine Val - Valine Trp - Tryptophan Tyr - Tyrosine Use standard single amino acid letter codes from this section to specify the target P-site sequences in. Section B under Option 1. Name of person completing this form Signature Date (Y/M/D)