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Four processes were needed for the spontaneous origin of life on Earth. #3 Origin of self-replicating molecules that made inheritance possible Read “Hunting the Replicators, How Did Life Begin?” and write a 5 sentence summary here. In living systems, information flows from _______ ________ _______________ What is RNA? Ribonucleic acid is a___________________ RNA is essential for _____________________________________ Like DNA, RNA is made up of a long chain of _________________ Each consists of a _______, a __________________ and a ____________ How is RNA different than DNA? RNA contains the sugar __________, while DNA contains the REVIEW: draw ribose slightly different sugar _____________ RNA has the base ____________ while DNA contains ___________________ Unlike DNA, most RNA molecules are ________________________ and can adopt very complex _______________________________ Remember, in living systems, information flows from _______ ________ _______________ This sequence probably developed in stages. RNA FIRST HYPOTHESIS 1. The first _______________________ and enzymes were RNA molecules 2. Why RNA? RNA can act as a catalyst to: a. Bind ____________________ together to form _______________ b. ______________________ itself to create more RNA 3. __________ can be transcribed to __________ (using reverse transcriptase); this could have given rise to the first DNA 4. DNA is more stable than RNA and eventually took over carrying the genetic information Arguments for the RNA First hypothesis • In Miller’s experiments, ___________ was created and _________________ was harder to produce. • ______ has a simpler structure then ________. • RNA exists in _______________ (and no DNA) • It has been proved experimentally that RNA has _____________________ • The DNA-protein system cannot work without ____________.