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Download Cardiff International School Dhaka (CISD) Lost Class Make Up
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Cardiff International School Dhaka (CISD) Lost Class Make Up Assignment Class: A2/A3 Subject: Chemistry Date: 22nd (Sunday)-28th (Saturday) March 2015 Total Mark- 20 Instructions: All of your assignment must be done in A4 size paper. Mention your Name, Class, Roll and Section clearly on the top sheet of your assignment. Submission Deadline: Saturday 28th March 10.00 AM to the respective subject teacher. The deadline is strict. Name:................................................................................................................................................. Class: .........................Roll: ........................ Sec: .................. Teacher: ...................................... Sunday-Saturday 22-28 March 2015 Lesson: 28.8 Genetic Mutations Task: Study – i. Explanation of genetic mutations ii. Sickle-cell anaemia iii. Cystic fibrosis iv. Modification of protein structure Worksheet/Exercise: Q1. Three levels of protein structure are primary, secondary and tertiary. a) Describe the primary structure of a typical protein containing one polypeptide chain. Name the type of chemical bonding involved in the primary structure of a protein. [4] b) Name 2 types of protein secondary structure. For each type give a named example and its location in the cell. Describe the bonding that stabilizes these secondary structures. [8] c) Describe four different types of interactions that maintain the tertiary structure of a protein. For each type of interaction give an explanation how the attractive forces arise. [8] Text Book/Reference Book: Chemistry Coursebook, Page No. 430 - 432, Chapter – 28 Answer Keys: Q1. a) The primary structure of a protein is the level of protein structure which refers to the specific sequence of amino acids. When two amino acids are in such a position that the carboxyl groups of each amino acid are adjacent to each other, they can be combined by undergoing a dehydration reaction which results in the formation of a peptide bond. Amino acids in a polypeptide (protein) are linked by peptide bonds that begin with the N-terminal with a free amino group and ends at C-terminal with a free carboxyl group. Chemical bonding involved are covalent bonds such as peptide bonds, which are made during the process of protein biosynthesis or translation. b) α-helix and β-pleated sheet structure c) Disulphide bridges, weak van der Waal’s forces, relatively weak hydrogen bonds, ionic bonds Help Lines: For any assistance, please contact Chemistry Teacher: Jobaida Akther, [email protected] Principal Head of School: G.M.Nizam Uddin, +88-01622181818, [email protected]