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Unit # 5 Cell Genetics Molecular Essential Questions: 1) How do living systems store, retrieve, and transmit genetic information critical to life processes? 2) How does the expression of genetic material control cell products which, in turn, determine the metabolism and nature of the cell? 3) What is the relationship between changes in genotype and phenotype and evolution? 4) How can humans use genetic engineering techniques to manipulate genetic information? What are the ethical issues raised by the application of these techniques? Big Idea 3: Living systems store, retrieve, transmit and respond to information essential to life processes. Essential knowledge DNA, and in some cases RNA, is the primary source of heritable information. . Learning Objectives: 1)The student is able to construct scientific explanations that use the structures and mechanisms of DNA and RNA to support the claim that DNA and, in some cases, that RNA are the primary sources of heritable information. 2) The student is able to justify the selection of data from historical investigations that support the claim that DNA is the source of heritable information. 3) The student is able to describe representations and models that illustrate how genetic information is copied for transmission between generations. 4)The student is able to describe representations and models illustrating how genetic information is translated into polypeptides. 5) The student can predict how a change in a specific DNA or RNA sequence can result in changes in gene expression. Essential knowledge: Changes in genotype can result in changes in phenotype. Learning Objectives: 1) The student can create a visual representation to illustrate how changes in a DNA nucleotide sequence can result in a change in the polypeptide produced.