Download Cell to cell junctions

CELL TO CELL JUNCTIONS
BY: ASHLEY COHN
SURFACE MARKERS
STRUCTURE
FUNCTION
EXAMPLE
VARIABLE, INTEGRAL
OR GLYCOLIPIDS
IDENTIFY THE CELL
MHC COMPLEXES,
BLOOD GROUPS,
ANTIBODIES
IN PLASMA
MEMBRANE.
SEPTATE JUNCTIONS/ TIGHT JUNCTIONS
STRUCTURE
FUNCTION
EXAMPLE
TIGHTLY BONDED,
LEAK PROOF,
FIBROUS CLAUDIN
PROTEIN THAT SEALS
THE CELL
HOLDS CELL
TOGETHER SO THAT
MATERIALS PASS
THROUGH BUT NOT
BETWEEN THE CELLS
JUNCTIONS
BETWEEN EPITHELIAL
CELLS IN THE GUT
ADHESIVE JUNCTION(DESMOSOME)
STRUCTURE
FUNCTION
EXAMPLE
VARIENT CADHERINS,
DESMOCOLLINS, BIND
TO INTERMEDIATE
FILAMENTS OF
CYTOSKELETON
CREATES STRONG
FLEXIBLE
CONNECTIONS
BETWEEN CELLS,
FOUND IN
VERTEBRATES
EPITHELIUM
• CADHERIN IS A PROTEIN WHICH
IS A CA2+ DEPENDENT
ADHESION MOLECULE WITH
VERY WIDE POLYGENETIC
DISTRIBUTION.
• DESMOSOMES ARE A
CADHERIN BASED JUNCTION
UNIQUE TO VERTEBRATES. THEY
CONTAIN THE CADHERIN'S
DESMOCOLLIN.
ADHESIVE JUNCTION ( ADHERENS JUNCTION)
STRUCTURE
FUNCTION
EXAMPLE
CLASSIC ADHERINS
BIND TO
MICROFILAMENTS
OF CYTOSKELETONS
CONNECTS CELLS
TOGETHER, OLDEST
FORM OF JUNCTION,
FOUND IN ALL
MULTICELLULAR
ORGANISMS
TISSUE WITH HIGH
MECHANICAL STRESS
SUCH AS THE SKIN
ADHESIVE JUNCTION
(HEMIDESMOSOMES, FOCAL ADHESION)
STRUCTURE
FUNCTION
EXAMPLE
INTEGRIN PROTEINS
BINDS CELL TO
EXTRACELLULAR
MATRIX
PROVIDE
ATTACHMENT TO A
SUBSTRATE
INVOLVED IN CELL
MOVEMENT AND
IMPORTANT DURING
DEVELOPMENT
COMMUNICATING JUNCTION (GAP JUNCTION )
STRUCTURE
FUNCTION
EXAMPLE
SIX TRANSMEMBRANE
CONNEXON
/PANNEXIN PROTEINS
CREATING A PORE
THAT CONNECTS
CELLS
ALLOWS FOR
PASSAGE OF SMALL
MOLECULES FROM
CELLS TO CELL IN A
TISSUE
EXCITABLE TISSUE
SUCH AS HEART
MUSCLE
•PANNEXINS ARE
PROTEIN FOUND IN
INVERTEBRATES
•CONNEXONS ARE A
PROTEIN IN
VERTEBRATES
COMMUNICATING JUNCTION ( PLASMODESMATA)
STRUCTURE
FUNCTION
EXAMPLE
CYTOPLASMIC
CONNECTIONS
BETWEEN GAPS IN
CONJOINING
PLANTS CELL WALLS
COMMUNICATING
JUNCTIONS
BETWEEN PLANT
CELLS
PLANT TISSUE
• PLASMODESMATA IS CYTOPLASMIC
CONNECTIONS THAT FORM ACROSS THE
TOUCHING PLASMA MEMBRANES
ALL INFORMATION IN THIS POWER
POINT CAN BE FOUND IN MGRAW
TH
HILL BIOLOGY 10 EDITION ON
PAGES 83-85