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Gamete Cell Division Meiosis Interphase Period of growth and synthesis (replication/duplication) of DNA Preparing the nucleus and cytoplasm for division Meiosis I Prophase I Nuclear membrane begins to break down Spindle fibers form Chromatin (a blob of) genetic material condenses making clear chromosomes Tetrad A set of 2 chromosome pairs Is a set of 4 individual chromosomes (has a centromere) or 4 individual chromatids (no centromere) Crossing over The exchange of material between a pair of chromosomes in a tetrad Source of variety in organisms Non-disjunction The tetrads of chromosomes do not separate properly Metaphase I The centrioles migrate to the cell poles The spindle fibers attach to the centromere of the chromosomes The tetrads line up across the equator Anaphase I The centrioles signal the spindle fibers to pull back The tetrads of chromosomes come apart Telophase I The spindle fibers go away The nuclear membrane regenerates Each new cell has 2 pairs of homologous (same structure) chromosomes *each new cell has a membrane Prophase II Spindle fibers form Nuclear membrane begins to break down Metaphase II The centrioles migrate to the cell poles The spindle fibers attach to the centromere of the chromosomes The homologous chromosomes line up across the equator Anaphase II The centrioles signal the spindle fibers to pull back The homologous chromosomes come apart Telophase II & Cytokinesis The spindle fibers go away The nuclear membrane regenerates Each new cell has 2 chromosomes *each new cell has a membrane