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2017 Phase 1 Revision Session Annie Evans and Decy Cotter 30/03/17 The Peer Teaching Society is not liable for false or misleading information… Organelles The Peer Teaching Society is not liable for false or misleading information… Nucleus Mitochondria Endoplasmic Reticulum Golgi Apparatus Lysosomes Cytoskeleton Cell Membrane Cell Membrane Cell Membranes DEFINITION!! Link cells that are subject to considerable stretching. Example: Squamous cells, like muscle DEFINITION!! Limit the passage of molecules through the extracellular space between the cells. Example: in the epithelial cells. DEFINITION!! Forms channels between the cytosols between the adjacent cells. Example: in the heart Endocytosis Endocytosis Receptors Cell Communication Peptide Hormone Steroid Hormone Positive Feedback Negative Feedback Water Homeostasis Definition Net movement of solvent molecules through a semipermeable membrane to a higher solute concentration. Definition Measure of the number of dissolved particles per kg of fluid. Definition Measure of the number of dissolved particles per L of fluid. Definition Pressure applied to a solution, by a pure solvent, required to prevent inward osmosis. Through a semipermeable membrane. Definition Form of osmotic pressure exerted by proteins that tends to pull fluid into its solution Sodium Potassium Calcium Definition!! Genetic constitution of an individual Definition!! Appearance of an individual. Combination of environmental and genetic factors Definition!! One of several alternative forms of a gene at a specific locus Definition!! Proportion of people with a gene/genotype who show the expected phenotype Definition Variation in clinical features (type and severity) of a genetic disorder between individuals with the same gene alteration Definition Expression of a particular characteristic limited to one of the sexes e.g sex characteristics BRCA. Definition Disease due to a combination of genetic and environmental factors Joke Time What’s red, hot swollen and painful? INFLAMMATION!! Changes During Inflammation Chemical Mediators of Inflammation What Happens Next? Exudate vs Transudate Things we didn’t cover • • • • • • • Angiotensin – Renin System Oedema Protein structure Forces and bonds DNA/RNA Production of proteins Mitosis and Meiosis DEFINTION ANSWERS! 1. Desmosomes 2. Tight junctions 3. Gap junctions 4. Genotype 5. Phenotype 6. Allele 7. Penetrance 8. Variable Expression 9. Sex Limitation 10. Multifactorial conditions DEFINITION ANSWERS! 1. 2. 3. 4. 5. Osmosis Osmolality Osmolarity Osmotic Pressure Oncotic Pressure