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Transcript
Name __________________________________ Ms. Foglia Period _________ Date ______________________ AP: CHAPTER 12: CELL CYCLE 1. What is meant by the concept that cells go through a cell cycle? __________________________________________________________________________ __________________________________________________________________________ 2. What are the key roles of cell division? __________________________________________________________________________ __________________________________________________________________________ 3. What is the significance of chromosome replication? __________________________________________________________________________ __________________________________________________________________________ 4. Sketch and label replicated chromosomes. 5. List the phases of the cell cycle with a brief description of what occurs in each phase. a. _______________________________________________________________________ b. _______________________________________________________________________ c. _______________________________________________________________________ d. _______________________________________________________________________ e. _______________________________________________________________________ 1 of 5 2004-2005 Name __________________________________ Ms. Foglia 6. Label the stages and key features of each stage. 2 of 5 2004-2005 Name __________________________________ Ms. Foglia 7. How does the spindle apparatus distribute chromosomes to the daughter cells? __________________________________________________________________________ __________________________________________________________________________ 8. What is the role of the kinetochores and the microtubules? __________________________________________________________________________ __________________________________________________________________________ 9. How does cytokinesis differ in animal and plant cells? Label the diagrams below. __________________________________________________________________________ __________________________________________________________________________ __________________________________________________________________________ 3 of 5 2004-2005 Name __________________________________ Ms. Foglia 10. Eukatyotic mitosis is thought to have evolved from _________________________________ 11. Why is the regulation of the cell cycle critical to normal cells? __________________________________________________________________________ __________________________________________________________________________ 12. What is the G1 checkpoint and where does it fit into the cycle? __________________________________________________________________________ __________________________________________________________________________ 13. What evidence is there that regulation is chemical in nature? __________________________________________________________________________ __________________________________________________________________________ __________________________________________________________________________ 14. Identify the role of the following in the cell cycle clock: a. Kinase _________________________________________________________________ __________________________________________________________________________ b. Cyclin _________________________________________________________________ __________________________________________________________________________ c. CDKs _________________________________________________________________ __________________________________________________________________________ 15. Describe the mechanism for regulating the passage of the cell into anaphase. __________________________________________________________________________ __________________________________________________________________________ 4 of 5 2004-2005 Name __________________________________ Ms. Foglia 16. Describe what triggers mitosis from G2. __________________________________________________________________________ __________________________________________________________________________ 17. What is the role of ubiquitin? __________________________________________________________________________ __________________________________________________________________________ __________________________________________________________________________ 18. Describe a model for an external signal for growth. __________________________________________________________________________ __________________________________________________________________________ __________________________________________________________________________ 19. What happens when cancer develops? __________________________________________________________________________ __________________________________________________________________________ __________________________________________________________________________ __________________________________________________________________________ 20. What is the role of p53? __________________________________________________________________________ __________________________________________________________________________ __________________________________________________________________________ 5 of 5 2004-2005