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I. Cellular respiration • The process of breaking down food to make energy. • Occurs in the mitochondria of the cell. • A process called glycolysis must take place first before it can happen. A. Glycolysis • The process of breaking down food, usually glucose. • Occurs in the cytoplasm of cells. • Doesn’t require oxygen. • The cell must borrow 2 ATP to start the process. • Creates a product called pyruvic acid. • The end product, pyruvic acid, will enter cellular respiration if oxygen is available in the cell. • 4 ATP is made but because 2 was borrowed, 2 must be paid back. Net gain is only 2ATP. B. Cellular respiration – Kreb Cycle • If oxygen is available in the cell, pyruvic acid will enter the mitochondria for aerobic cellular respiration. • The first step is the Kreb cycle. • The Kreb cycle produces some ATP but also produces carbon dioxide. This carbon dioxide is a waste product of the Kreb cycle that we exhale. • The products NADH and FADH2 will then enter the electron transport chain. C. Cellular Respiration – electron transport chain (ETC) • When the kreb cycle is done, the 2nd step of cellular respiration occurs. The electron transport chain. • In this 2nd step, the most number of ATP is produced. About 36 molecules of ATP is made. More or less can be made depending on the type of cell. A fat cell will make less ATP than a muscle cell. • In addition to making ATP water is also produced. • NADH and FADH2 drops of the “hydrogen” becoming NAD and FAD to pick up more “hydrogen”. II. What if there’s no oxygen? • After glycolysis, if oxygen is not available in the cell pyruvic acid will enter an alternate pathway called Anaerobic Fermentation. • There are two types: – Alcoholic fermentation (how beer, wine and cider is made). – Lactic acid fermentation (done by animals & yeasts) • the cramping you feel in your muscle after heavy heavy exercise… “charlie horse” • How sour foods such as sauerkraut, dry sausages, kimchi, yogurt and other pickled foods • Fermentation is important because it produces NAD+ which is needed to keep glycolysis running until oxygen becomes available.