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Bell Work Transcription occurs in the ________, creating a single stranded ________. This _______ contains the Nitrogen base ______ instead of __________. Word Bank: Uracil, DNA, mRNA, Adenine, Guanine, Nucleus, Cytoplasm, Thymine Translation: • decoding of an mRNA message into a polypeptide(Protein) chain • occurs on a ribosome (OUTSIDE the nucleus) Translation: 1. mRNA travels to the ribosome 2. transfer RNA (tRNA) brings amino acids to the ribosome 3. polypeptide (protein) is formed Codon: three consecutive mRNA bases Ex: GCU Anticodon: three complementary tRNA bases Codon GCU CGA Anticodon •tRNA looks for the codon that pairs with its anticodon • the ribosome takes the amino acid and attaches it to the polypeptide chain ORDER MATTERS! order of DNA bases order of RNA bases order of amino acids what protein is made tRNA Amino acids mRNA How to use the Codon Chart: 1. Use the left side to find the first letter in the codon 2. Use the top to find the second letter in the codon 3. Use the right side to find the third letter of the codon 4. Go to where ALL three overlap on the chart Did you notice?: The codon “AUG” can specify methionine or serve as the “start” codon for protein synthesis. How to use the Codon Wheel: 1. Begin in the middle with the first letter of the codon 2. Go outward to the second letter in the codon 3. Go outward again to the third letter in the codon. What other codons will tell the ribosome to stop putting amino acids together? What DNA sequences will give you these codes?