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Transcript
Odor responses in the olfactory bulb. A. The axons from neurons in one epithelial zone with the same odorant receptor type usually converge to two glomeruli, one on each side of the olfactory bulb. Here a probe specific for one odorant receptor gene labeled a glomerulus on the medial side (left) and lateral side (right) of a mouse olfactory bulb. The probe hybridized to receptor messenger RNAs present in sensory axons in these coronal sections. (Adapted from Ressler, Sullivan, and Buck 1994.) B. This section of a rat olfactory bulb shows the uptake of radiolabeled 2-deoxglucose at multiple foci (red) following exposure of the animal to the odorant methyl benzoate. The labeled correspond to numerous glomeruli of at Neural different locations the olfactory bulb. (Reproduced, with permission, from Source: Smell and foci Taste: The Chemical Senses, Principles Science, FifthinEditon Johnson, Farahbod, and Leon 2005.) Citation: Kandel ER, Schwartz JH, Jessell TM, Siegelbaum SA, Hudspeth AJ, Mack S. Principles of Neural Science, Fifth Editon; 2012 Available C. The olfactory bulb has a precise map of Accessed: odorant receptor inputs at: http://mhmedical.com/ June 11, 2017because each glomerulus is dedicated to only one type of receptor. The maps in the two olfactoryCopyright bulbs are©bilaterally symmetrical and are nearly identical 2017 McGraw-Hill Education. All rights reservedacross individuals. The maps on the medial and lateral sides of each bulb are similar, but slightly displaced along the dorsal-ventral and anterior-posterior axes.