* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download The Art of Looking at Cells
Survey
Document related concepts
Tissue engineering wikipedia , lookup
Signal transduction wikipedia , lookup
Cell nucleus wikipedia , lookup
Extracellular matrix wikipedia , lookup
Cell membrane wikipedia , lookup
Cell encapsulation wikipedia , lookup
Cellular differentiation wikipedia , lookup
Cell growth wikipedia , lookup
Cell culture wikipedia , lookup
Organ-on-a-chip wikipedia , lookup
Cytokinesis wikipedia , lookup
Transcript
BIOLOGY CONCEPTS & CONNECTIONS Fourth Edition Neil A. Campbell • Jane B. Reece • Lawrence G. Mitchell • Martha R. Taylor CHAPTER 4 A Tour of the Cell Modules 4.1 – 4.5 From PowerPoint® Lectures for Biology: Concepts & Connections Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings The Art of Looking at Cells • Artists are often inspired by biology and biology depends on art • The paintings of Wassily Kandinsky (1866-1944) show the influence of cellular forms Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings • Illustration is an important way to represent what scientists see through microscopes • The anatomist Santiago Ramón y Cajal (18521934) was trained as an artist – He drew these retina nerve cells Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings INTRODUCTION TO THE WORLD OF THE CELL • The microscope was invented in the 17th century • Using a microscope, Robert Hooke discovered cells in 1665 • All living things are made of cells (cell theory) Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings 4.1 Microscopes provide windows to the world of the cell • The light microscope enables us to see the overall shape and structure of a cell Image seen by viewer Eyepiece Ocular lens Objective lens Specimen Condenser lens Light source Figure 4.1A Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings • Electron microscopes were invented in the 1950s • They use a beam of electrons instead of light • The greater resolving power of electron microscopes – allows greater magnification – reveals cellular details Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings • Scanning electron microscope (SEM) • Scanning electron micrograph of cilia Figure 4.1B Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings • Transmission electron microscope (TEM) • Transmission electron micrograph of cilia Figure 4.1C Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings 4.2 Cell sizes vary with their function • Below is a list of the most common units of length biologists use (metric) Table 4.2 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings • Cell size and shape relate to function • 250 bacteria would stretch across the high power field of your microscopes. • 50 animal cells would stretch across that same field. Figure 4.2 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Is there a limit to cell size? Can you have a giant man eating mouse? Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings 4.3 Natural laws limit cell size • At minimum, a cell must be large enough to house the parts it needs to survive and reproduce • The maximum size of a cell is limited by the amount of surface needed to obtain nutrients from the environment and dispose of wastes Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings • A small cell has a greater ratio of surface area to volume than a large cell of the same shape 30 µm Figure 4.3 Surface area of one large cube = 5,400 µm2 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings 10 µm Total surface area of 27 small cubes = 16,200 µm2 4.4 Prokaryotic cells are small and structurally simple • There are two kinds of cells: prokaryotic and eukaryotic. Most cells are 70% water by weight, 18% protein, 3% lipids, 2% polysaccharides, 1.1% RNA and .25% DNA. • Prokaryotic cells are small, relatively simple cells. • The smallest prokaryotes are bacteria called mycoplasmas which are 2 micrometers in diameter. • Prokaryotes do not have a nucleus or membrane bound organelles. • Prokaryote means “before the kernel” Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings • A prokaryotic cell is enclosed by a plasma membrane and is usually encased in a rigid cell wall – The cell wall may be covered by a sticky capsule Prokaryotic flagella-for movement Ribosomes-site of protein synthesis Capsule-protection Cell wall-protection – Inside the cell are its DNA and other parts Plasma membrane Pili-for attachement Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Nucleoid region (DNA) Figure 4.4 4.5 Eukaryotic cells are partitioned into functional compartments • All other life forms are made up of one or more eukaryotic cells • These are larger and more complex than prokaryotic cells averaging 10-100 micrometers. • The largest cells include the nerve cell in the leg of a giraffe which is 2 meters long. • Eukaryotes are distinguished by the presence of a true nucleus Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings • An animal cell Smooth endoplasmic reticulum Nucleus Rough endoplasmic reticulum Flagellum Not in most plant cells Lysosome Centriole Ribosomes Peroxisome Microtubule Cytoskeleton Intermediate filament Microfilament Figure 4.5A Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Golgi apparatus Plasma membrane Mitochondrion • The plasma membrane controls the cell’s contact with the environment • The cytoplasm contains organelles • Many organelles have membranes as boundaries – These compartmentalize the interior of the cell – This allows the cell to carry out a variety of activities simultaneously. ie. Poisonous H2O2 made in the peroxisomes while hormones are being folded in the endoplasmic reticulum. – Many organelles have fluid filled spaces-this allows for activities termed cellular metabolism – Membranes allow for surfaces for metabolic processes to occur. Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings • A plant cell has some structures that an animal cell lacks: – Chloroplasts – site of photosynthesis – A rigid cell wall with cellulose – Central vacuole for storage of water and chemicals – Lack centrioles seen during cell division Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Nucleus Rough endoplasmic reticulum Ribosomes Smooth endoplasmic reticulum Golgi apparatus Microtubule Not in animal cells Central vacuole Intermediate filament Chloroplast Microfilament Cell wall Mitochondrion Peroxisome Plasma membrane Figure 4.5B Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Cytoskeleton