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Proteins What are proteins? • Chain of molecules of Amino Acids called a polypeptide chain • Found in: muscle, hormones, enzymes • Monomers of proteins are amino acids – 20 total AA Major Functions of Proteins 1. Provide energy 2. Enzyme catalyst: speed up rxn 3. Defense: use shape to recognize foreign invaders 4. Transport: hemoglobin-oxygen to RBC 5. Support: fibrous proteins 1. Fibrin in blood clots 2. Collagen-matrix of skin Amino Acids • Monomers of Proteins • All contain: 1. Amino group NH2 2. Carboxyl group –COOH 3. R group -different for every AA -determines the properties of AA Joined together by peptide bonds Peptide Bonds • Amino acids join together by peptide bond • Forms when amino end of one AA joins to carboxyl end of another AA by dehydration synthesis. http://science.nhmccd.edu/BioL/dehydrat/dehydrat.html • Protein structures As AA join, R groups interact and cause molecules to bond 1. 2. 3. 4. Primary-straight chain Secondary-helix Tertiary-mass Quaternary-2 proteins combined Enzymes • All enzymes are proteins • Speed up chemical rxn; catalyst • Shape of protein allows it to bond to specific molecules called substrates, causes a change in shape Examples maltase: breaks down maltose into 2 glucose lipase: breaks down lipids into fatty acids protease: breaks down proteins into amino acids **works best under certain temperatures or pH Enzymes