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8.3 DNA Replication
___________________________copies the genetic information.
A single strand of DNA serves as a template for a new strand.
The rules of base pairing direct replication.
DNA is replicated during the ______________________________stage of the cell cycle.
Each body cell gets a complete set of _________________________ DNA.
During DNA replication:
1.The DNA is unwound and unzipped by the enzyme
_______________________.
The strands are held apart by single-stranded binding proteins (also
known as ssbps)
2. Each original DNA strand is used as a ____________________________(or model) to make a new DNA strand with
base pairing
3. The enzyme _________________________ lays down an RNA Primer a few base pairs long to which the new DNA can
be added.
4. Another enzyme, called _______________________________, adds new _____________________ to the RNA
Primer.
It always reads ________to _________________ and synthesizes the new strand from _________ to _____________
This occurs in the direction following ________________________ opening up the “replication fork”. For this reason,
the new strand is called the _______________________________.
5. Another DNA Polymerase also “proofreads” the new DNA to check for
errors.
6. Meanwhile, on the other strand, known as the
_________________________, Primase and DNA Polymerase synthesize
DNA from 5’ to 3’ away from the replication fork.
These small spurts of replication form what are known as ___________________________________________
** DNA Polymerase only works in one direction. One strand is read and synthesized
______________________________ while the other is synthesized in ____________________________.
7. The Okazaki fragments are joined together by the enzyme ___________________________.
8. On both strands, the RNA Primer is replaced with DNA nucleotides by the enzyme DNA Polymerase.
When replication is complete, each DNA molecule is made of one _________________________ and one
_______________________. This is described as the _________________________________ model of replication.
9. The new DNA molecules are rewound by the enzyme ______________________________________
Replication is fast and accurate.
DNA replication starts at _____________________________________ in eukaryotic chromosomes.
DNA polymerases can find and correct errors