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Name: _____________________ Class: ______ Date: _________________________ DNA REPLICATION PRE/POST-TEST BENCHMARK COVERED: SC.912.L.16.3 Describe the basic process of DNA replication and how it relates to the transmission and conservation of the genetic information. Part 1. Multiple Choice (15 POINTS) DIRECTIONS: Write the letter of the BEST ANSWER beside each number of each the question. 1. Genes for medically important proteins can be cloned and inserted into bacteria, as shown in the diagram on the right. Why can bacteria recognize a human gene and then produce a human protein? A. DNA replication in bacteria and humans is the same. B. Bacterial cells contain the same organelles as human cells. C. The basic components of DNA are the same in humans and bacteria. D. Bacterial cells and human cells contain the same kind of chromosomes. 2. Which type of molecule contains genetic information that is passed from parents to offspring? A. Fat molecules B. DNA molecules C. Protein molecules D. Carbohydrate molecules 3. What is the genetic code? A. The sequence of subunits in a DNA molecule B. The number of subunits in a DNA molecule C. The sequence of subunits in a protein molecule D. The number of subunits in a protein molecule 4. Humans, butterflies, and trees are all living things. In which of these organisms would you find DNA molecules? A. Only in humans B. Only in humans and butterflies C. In humans, butterflies, and trees D. In none of these organisms 5. DNA molecules are made up of subunits called nucleotides that are linked together. How many different types of nucleotides are used to make DNA molecules? A. One type B. Two types C. Three types D. Four types 6. Which of the following describes the relationship between chromosomes and DNA molecules? A. Each chromosome is made of a single DNA molecule. B. Each chromosome is made of more than one DNA molecule. C. Each DNA molecule is made of more than one chromosome. D. There is no relationship between chromosomes and DNA molecules. 7. What are the subunits that make up DNA molecules? A. Amino acids B. Nucleotides C. Fatty acids D. Proteins 8. Which of the following contain hereditary information? A. Chromosomes and genes B. Chromosomes but not genes C. Genes but not chromosomes D. Neither chromosomes nor genes 9. In humans, where does DNA replication take place? A. Cytoplasm B. Ribosomes C. Nucleus D. Cell membrane 10. How many amino acids are coded for the strand of mRNA show below? Assume the reading frame begins with the first nucleotide. CGAUAC A. 1 B. 2 C. 3 D. 6 11. Which of the following are found in both DNA and RNA? A. ribose, phosphate groups, and adenine B. deoxyribose, phosphate groups, and guanine C. phosphate groups, guanine, and cytosine D. phosphate groups, guanine, and thymine 12. Which nucleotide in the figure below indicates the nucleic acid above is RNA? A. Uracil B. Cytosine C. Guanine D. Adenine 13. There are 64 codons and 20 amino acids. Which of the following is true? A. Several different codons can specify the same amino acid. B. Each codon specifies a different amino acid. C. Some amino acids have no link to a codon. D. Each amino acid is specified by only one codon. 14. During translation, the type of amino acid that is added to the growing polypeptide depends on the A. codon on the mRNA and the anticodon on the rRNA. B. anticodon on the mRNA and the anticodon on the tRNA. C. anticodon on the rRNA and the codon on the mRNA. D. codon on the mRNA and the anticodon on the tRNA. 15. In eukaryotes A. Transcription takes place in the cytoplasm, and translation takes place in the nucleus. B. Transcription takes place in the nucleus, and translation takes place in the cytoplasm. C. Proteins are produced. D. Transcription and translation both take place in the nucleus. E. Transcription and translation both take place in the cytoplasm. ANSWER KEY Part 1: Multiple Choice 1. 2. 3. 4. 5. 6. 7. 8. C B A C D A B A 9. C 10. B 11. C 12. A 13. B 14. A 15. B Part 2: Using Science Skills 1. Interpret Visuals What is structure E in Figure A? What does it specify? Structure E is the start codon, which specifies the amino acid methionine. 2. Predict What would happen to structure F in Figure A if structure C were deleted? The base sequence of the codon (structure F) would change from GCU to GUG. 3. Predict In Figure A, what effect would the deletion of structure C have on the process that occurs during step Y? The deletion of structure C would shift the reading frame of the codons during translation. As a result, the sequence of the amino acids that follows after structure C might change.