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NAME _______________________________________________ CH. 8 HONORS STUDY GUIDE SCIENTISTS: 1. Hershey & Chase experiment – describe the bacteriophages used in their experiment. 2. Watson & Crick experiment explain what happened. CENTRAL DOGMA: 1. Explain how information flows in the Central Dogma. 2. Where does DNA replication take place for eukaryotic organisms? 3. During what part of the cell cycle will replication take place & how many times? 4. After replication, explain how the new & old strands of DNA are arranged. 5. What is the function of the enzyme DNA polymerase? 6. Explain Chargaff’s rule. 7. List the things that DNA nucleotides are composed of. 8. List the things that RNA nucleotides are composed of. 9. Describe the DNA double helix. 10. DNA strand: T T A G C T A T A G C C G T A WRITE: the complementary DNA strand: 11. Using the DNA strand above, WRITE: the complementary RNA strand: 12. What is the job of the mRNA? 13. What is the job of rRNA? 14. What is the job of tRNA? 15. What RNA molecules are involved in protein synthesis? 16. Which RNA molecule functions as the blueprint of the genetic code? 17. Where is mRNA edited? Explain what is removed & what is put back together. 18. What nucleotide bases are found in DNA? _____________________________ RNA? ___________________ 19. Name the process that is taking place in the picture to the right. 20. Describe the relationship between a codon & an anticodon. 21. Compare & contrast a DNA molecule with a RNA molecule. GENETIC CODE: 1. How many bases are needed to code for one amino acid? 2. Using the genetic code to the right or from your textbook, write the correct amino acid sequence for the following mRNA strand: AUGCCGAAAGGGUAG MUTATIONS: 1. List & explain the different types of gene mutations. 2. Explain how a frameshift mutation affects the reading frame. 3. List & explain the different types of chromosomal mutations. 4. In the boxes, label the different types of chromosomal mutations in this picture. DEFINITIONS: 1. Base pairing rules: 2. Codon: 3. Replication: 4. Transcription: 5. Translation: