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Fall Semester Exam Review Congratulation!!!…You made it to the end of the first semester of pre-AP Biology and now you get the opportunity to demonstrate your knowledge in biology. Unfortunately for you, EVERYONE will take the semester exam, regardless if you are exempt or not, EVERYONE will take the exam. This review will help you to test your knowledge of every single concept we covered during the semester. Some concepts and ideas are not included in this review, which means you do not have to stress about them. The review is divided in Units, six units in total. Each unit contains a required vocabulary that you have to be familiar with and some questions that will help you to apply your knowledge. Bonus Points: If you turn in this review the day of the test (TBA), you will get 5 extra points in your Semester Exam and it can replace your lowest quiz grade of the Six-Weeks with a 100. Good Luck and if you need help, you can always come to tutorials before and after school. Biochemistry Vocabulary Biochemistry Carbohydrates Monomer Polymer Atom Proteins Nucleic Acid Enzyme Biomolecule Lipids Peptide Chemical Reaction Reactants Products Law of Conservation of Energy Activation Energy Catalyst Substrate Inhibitor Denature Questions What are the monomer and polymer of each biomolecule? What are the functions of each biomolecule? How can you distinguish between saturated and unsaturated lipids? Why are the four types of protein structure different? Why are proteins different? What are the elements found in each type of biomolecule? Write two example molecules for each biomolecule. What is the function of an enzyme? What the two types of chemical reactions? Why do they depend on activation energy? What are the three key characteristics of an enzyme? What is the Enzyme/Substrate Complex? Explain each part of the complex. How can you modify or disrupt the activity of an enzyme What is the role of an Enzyme in a chemical reaction? What would that look like on in the form of a line graph (Y axis is RATE OF REACTION and X axis is % of CONCENTRATION? Biological Macromolecule Function(s) Monomer Examples Carbohydrate Lipids Proteins Nucleic Acids Cell Structure and Transport Vocabulary Cell Prokaryotic Cell Organelle Nucleus Eukaryotic Cell Chromatin Nuclear Membrane Nucleolus Mitochondria Ribosomes Rough Endoplasmic Reticulum Smooth Endoplasmic Reticulum Golgi Apparatus Vacuoles Lysosomes Cytoskeleton Chloroplast Cell Wall Photosynthesis Cellular Respiration Cell Membrane Cytoplasm Protein Channel Active Transport Passive Transport ATP DNA Diffusion Osmosis Concentration Gradient Synthesis Homeostasis Isotonic Hypertonic Hypotonic Phospholipid Solution Solute Solvent Questions What are the differences and similarities between eukaryotic and prokaryotic cells? What organelles can be found in plants only? Where can you find ribosomes in a cell? Why is photosynthesis and cellular respiration important for organisms? Write the formula for each chemical reaction. What are the differences between Passive and Active transport? What is a cell membrane made of? What are the functions of each part? Draw a diagram that illustrates a cell in an isotonic, hypotonic, and hypertonic solution. What is the importance of ATP? Provide 3 examples. Why is active transport and passive transport necessary to keep homeostasis in a cell? Prokaryotic Eukaryotic Examples Main Characteristics of each DNA Structure and Protein Synthesis Vocabulary DNA Nucleotide Nitrogenous Bases DNA Backbone Purine Pyrimidine Hydrogen Bond Chargaff’s Rule Cell Cycle Zygote Genome Interphase Mitotic Phase Cytokinesis Mitosis DNA Chromatin Chromosomes Histone Gene Cancer Sister Chromatids Gene Expression Central Dogma Transcription Translation Ribosomes RNA DNA mRNA tRNA Pre-mRNA Ribozyme Codon Anticodon Template Strand RNA Polymerase TATA Box Spliceosome Polypeptide Mutations Point Mutations Operon Alleles Questions Draw and describe the structure of DNA. Why are Nitrogenous bases important? Draw the structure of a Nucleotide. What kind of biomolecule is DNA? What is the function of Cell Division? What kinds of cells perform cell division, especially mitosis? Develop a concept map that shows the steps of cell division and describe their main function. You must include all the correct terminology. Total number of terms: 12 Terms How many chromosomes are found in cells that under mitosis? What is the purpose of the central dogma? What are the differences between DNA and RNA? What are the differences and similarities of protein synthesis between prokaryotes and eukaryotes? Draw a diagram showing the steps of protein synthesis. Include all the correct terminology. Number of terms: 10 terms (minimum). What are the different types of point mutation? Explain the 5 different types. Why do you want to regulate gene expression? Why do you want to synthesize proteins? What are the different types of gene control? Why animals, plants, and bacteria (different organisms) share the same genetic bases? A nucleotide is composed of the following parts: a. Label X, Y and Z in the following diagram: What is the complimentary strand of this DNA segment: 5’ A-C-A-C-T-G-T-A-G-T-C-A-C-T-G-A-C-A-T-G-C 3’ Before DNA can replicate in the S phase, this enzyme must “un-zip” the DNA: ___________. After this enzyme unzips the DNA, another enzyme called _________________ replicates the DNA material by creating new nucleotides. Explain the purpose and where each process takes place: Transcription Translation Purpose: Purpose: Where does this take place: Where does this take place: If the mRNA 5’ AUGACUAAU 3’ had a mutation to 5’ AUGACCAAU 3’ what would be the effect? If the mRNA 5’ AUGACUAAU 3’ had a mutation to 5’ AUGACCAAA 3’ what would be the effect? Unit 2.3 Meiosis and Mitosis Vocabulary Meiosis Somatic Cells Gametes Sexual Reproduction Asexual Reproduction Diploid Haploid Fertilization Crossing Over Independent Assortment Genes Chromosomes Homologous Chromosomes Autosomes Sex Chromosomes Karyotype Cancer Life Cycle Zygote Synapsis Chiasmata Tetrad Sister Chromatids Genetic Variation Questions Develop a concept map that shows the steps of the life cycle and describe their main function. You must include all the correct terminology. Total number of terms: 15 Terms Why does cell needs to have meiosis 1 and meiosis 2 during gamete formation? What steps of gamete formation are unique to meiosis? How many chromosomes are found in human cells after meiosis? How can gametes end up with different genes/genetic information, even that the can be formed from the same cell? What is the purpose of the terms “n” and “2n”? Complete the following diagram with the correct number of human chromosomes. Use the picture and chart below to describe the steps of the Cell Cycle. Interphase Prophase Metaphase Anaphase Telophase Cytokinesis Mendel and Genetics Vocabulary Gene Alleles Phenotype Genotype P Generation F1 Generation F2 Generation Dominant Allele Homozygous Dominant Gene Recessive Alleles Homozygous Recessive Gene Heterozygous Gene Law of Segregation Punnett Square Test Cross Law of Independent Assortment Monohybrid Cross Dihybrid Cross Complete Dominance Codominance Incomplete Dominance Multiple Alleles Polygenic Inheritance Pedigree Autosomal Recessive Disorder Autosomal Dominant Disorder Nature and Nurture Questions (Monohybrid Crosses) Set up the Punnett squares for each of the crosses listed below. Round seeds are dominant to wrinkled seeds. Rr x rr What percentage of the offspring will be round? RR x rr What percentage of the offspring will be round? (Dihybrid Crosses) In guinea pigs the allele for black fur (B) is dominant over the allele for brown fur (b), and the allele for short fur (F) is dominant over the allele for long fur (f). If a male guinea pig that is heterozygous for both traits mates with a female that has long brown fur, what are all the possible genotypes of their offspring? (HINT: fill in the dihybrid cross square below) a. What percentage of the offspring from a BbFf x bbff cross would be expected to be heterozygous for both traits? b. What are all the possible phenotypes from this cross? A man who is heterozygous with type A blood marries a woman who is homozygous with type B blood. What possible blood types might their children have? Phenotype Genotype(s) (Blood Group) Type A IAIA or IAi Type B IBIB or IBi Type AB IAIB Type O ii If several pea plants with the genotype T TYy are crossed with pea plants with the genotype Ttyy, what percentage of the offspring will be expected to have the T TYy allele combination? Fur color in cats is controlled by an autosomal gene that can occur in the dominant form, (B), or the recessive form, (b). The length of the cat’s fur is controlled by another autosomal gene that occurs in the dominant form, (S), or the recessive form, (s). The table below shows the traits for these allele codes Gene Trait B black fur b white fur S short-haired fur s long-haired fur The following genotypes were found in a male cat and a female cat. Male cat Female cat BbSs bbSS Which one of the following choices is true of the phenotype of offspring when the male and female cats are crossed?