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Vocabulary Watson & Crick Codon DNA replication mRNA tRNA rRNA DNA Protein Polypeptide Peptide Bond amino acids nucleotide transcription translation point mutation Double Helix mutation frameshift mutation hydrogen bond Complementary base pairing Objective Biology Curriculum 3.01 Analyze Instruction SHOULD include: Compare and contrast the structure of DNA and as compared to RNA. the molecular Identify complementary base pairing between nucleotides. basis of Illustrate that the sequence of nucleotides in DNA codes for proteins – (2004 the central key to cell function and life. heredity Edition) Explain how the process of DNA replication allows daughter cells to including: have an exact copy of parental DNA. CH 11, Describe the semi-conservative nature of the replication process. DNA 281-301 (nature of the process, not the term semi-conservative) Identify that mutations are a change in the DNA code. Replication Protein Synthesis (transcription & translation) Gene Regulation Asexual / Sexual Reproduction chromosomes chromatin chromatid interphase prophase metaphase anaphase telophase cytokinesis mitosis meiosis centromere fertilization nondisjunction zygote haploid diploid gametes somatic cells Related Chapters Point out the position of DNA replication within the cell cycle. Show the importance of relatively weak hydrogen bonds. Illustrate that transcription that produces an RNA copy of DNA, which is further modified into the three types of RNA mRNA traveling to the ribosome (rRNA) Translation - tRNA supplies appropriate amino acids Show that amino acids are linked by peptide bonds to form polypeptides which are folded into proteins. Use of a codon chart to determine the amino acid sequence produced by a particular sequence of bases. Demonstrate that all (with a few exceptions) of an organism’s cells have the same DNA but differ based on the expression of genes. Differentiation of cells in multi-cellular organisms Cells respond to their environment by producing different types and amounts of protein. Discuss advantages (injury repair) and disadvantages (cancer) of the overproduction, underproduction or production of proteins at the incorrect times Instruction SHOULD include: 3.02 Compare and Recognizing mitosis as a part of asexual reproduction and meiosis as a contrast the part of sexual reproduction. Similarities and differences between mitosis and meiosis including characteristic replication and separation of DNA and cellular material, changes in s of asexual chromosome number, number of cell divisions, and number of cells and sexual produced in complete cycle. Putting mitosis diagrams in order and describing what is occurring reproduction. throughout the process. The sources of variation including: Crossing over. Random assortment of chromosomes. Gene mutation Nondisjunction Fertilization Types of Asexual Reproduction: Regeneration Vegetative Propagation Budding Binary Fission Sporulation (spores) (2004 Edition) CH 8.28.3, 201213 CH 10, 10.2, 263-273 Homozygous heterozygous Recessive Dominant Gregor Mendel Carrier Hemophilia PKU Multiple Alleles Sex-linked traits heredity allele phenotype genotype Punnett Square Cystic Fibrosis karotype Down Syndrome autosome incomplete dominance Co dominant polygenic inheritance genetics pedigree Sickle Cell Anemia Color blindness sex chromosomes 3.03 Interpret Instruction SHOULD include: Identify and determine genotypes and phenotypes. and predict Recognize that phenotype is the result of both genotype and the patterns of environment. inheritance. Discuss Mendel’s experiments and laws. Dominant, recessive and intermediate traits. Multiple alleles. Polygenic traits. Sex linked traits Independent assortment. Test cross. Pedigrees. Punnett squares. (2004 Edition) Interpret karyotypes (gender, chromosomal abnormalities) Understand that dominant traits mask recessive alleles. CH 10, There are a variety of intermediate patterns of inheritance, including 10.1, codominance and incomplete dominance. 253-262 Incomplete dominance (also called partial dominance) results in the blending of traits. (Usually results from an inactive or less active gene CH 12, so the heterozygous phenotype appears intermediate. E.g. Pink flowers) 309-329 Co-dominant alleles result in the expression of both traits. (two different proteins are produced and both are detected e.g. roan cows and AB blood type.) Autosomal inheritance patterns and characteristics of sickle cell anemia, cystic fibrosis, and Huntington’s disease Solve and interpret co-dominant crosses involving multiple alleles. A, B, AB and O blood types (alleles: IA, IB, and i). Determine if parentage is possible based on blood types. Some traits are controlled by more than one pair of genes. This pattern of inheritance is identified by the presence of a wide range of phenotypes (consider examples of skin and hair color). An understanding of human sex chromosomes. Solving crosses involving sex linked traits (examples: color-blindness and hemophilia.) Understand why males are more likely to express a sex-linked trait. The importance of the genes being on separate chromosomes as it relates to meiosis. How the process of meiosis leads to independent assortment and ultimately to greater genetic diversity. Given certain phenotypes suggest an appropriate test cross to determine the genotype of an organism. Identify the genotypes of individuals from a given pedigree. (students should be able to interpret pedigrees which show phenotype not genotype) Solving and interpreting problems featuring monohybrid crosses. (Parental, F1, F2 generations) Determining parental genotypes based on offspring ratios. Test Cross Recombinant 3.04 Assess Instruction SHOULD include: DNA The reasons for establishing the human genome project. Ethical issues the impacts Gene Therapy and implications of genomics and biotechnology. Clone of genomics Recognition that the project is useful in determining whether Plasmid on individuals may carry genes for genetic conditions and in developing Restriction gene therapy. individuals Enzyme Gel electrophoresis as a technique to separate molecules based on size. Human Genome and society. Uses of DNA fingerprinting Project Applications of transgenic organisms (plants, animals, & bacteria) in Gel Human agriculture and industry including pharmaceutical applications such as Electrophoresis genome the production of human insulin. Genetically project. Ethical issues and implications of genomics and biotechnology. (stem Modified cell research and genetically modified organisms) Organisms Applications Genetic of Engineering biotechnology. Vector Transgenic Organisms DNA fingerprinting (2004 Edition) CH 13.213.3, 341-353 Biogenesis Abiogenesis 3.05 Examine Instruction SHOULD include: Miller & Urey the (2004 Fossils development Historical development of the theory of evolution by Edition) Relative Dating of the theory natural selection. Absolute Dating of evolution Biogenesis in contrast to abiogenesis with emphasis CH 15, Speciation 393-413 Charles Darwin by natural on the experiments used to support both ideas. selection natural Early atmosphere hypotheses and experiments. Selection including: How the early conditions affected the type of Homologous organism that developed (anaerobic and prokaryotic). Structure Developme Evolution of eukaryotic and aerobic organisms. Vestigial nt of the Structure Fossils– relative and absolute dating methods theory. Geographic A discussion of what can be inferred from patterns in isolation The origin the fossil record. Divergent and history Biochemical similarities. Evolution of life. Shared anatomical structures. Convergent Evolution How variations provide material for natural selection. Fossil and Camouflage biochemical The role of geographic isolation in speciation. Analogous evidence. The importance of the environment in selecting Structure adaptations. Adaptive Mechanism Radiation Discuss the evolutionary selection of resistance to s of Gradualism evolution antibiotics and pesticides in various species. mimicry embryo Application Directional s (pesticide selection & antibiotic stabilizing resistance). selection Punctuated Equilibrium Goal Vocabulary 2 2 2 Organic Compound Inorganic Compound Cellulose insulin glycogen glucose Protein Amino Acid acid/base starch lipid/fat hemoglobin Nucleic Acid DNA/RNA Organelle Chromatin Plasma Membrane Prokaryote Eukaryote nucleus ribosome mitochondria vacuole cytoplasm cell wall chloroplast hormone Diffusion Facilitated Diffusion Selectively Permeable Passive transport Active Transport Homeostasis Phospholipid Osmosis ATP/ADP Enzyme Related Chapters Course Objective Biology Curriculum 2.01 Compare and contrast the structure and functions of the following organic molecules: Carbohydrates. Proteins. Lipids. Nucleic Acids Instruction SHOULD include: 2005 1. Examine the role and importance of organic molecules Edition to organisms. CH 6, 6.3, 2. Examples to investigate include starch, cellulose, 157-163 insulin, glycogen, glucose, enzymes, hemoglobin, fats, DNA and RNA. 3. Interpret results of tests for starch (iodine), lipids (brown paper), monosaccharides (Benedict’s Solution), and protein (Biuret’s). Instruction SHOULD include: 1. Identify and give the structure and function of the following cell organelles: nucleus, plasma membrane, 2005 cell wall, mitochondria, vacuoles, chloroplasts and the Edition ribosomes. 2. Proficient use and understanding of light microscopic CH 7, 171techniques. Students should determine total power 187 magnification as well as steps in proper microscope usage. 3. Hierarchy of cell organization: Cells tissuesorgans organ systems. 4. Structure of cells as it relates to their specific functions. 5. Students should view a variety of cells with particular emphasis on the differences between plant and animal cells. 6. Chemical signals may be released by one cell to influence the activity of another cell. 7. Know the role of receptor proteins 8. Know the role of hormones 2.03 Investigate Instruction SHOULD include: and analyze the cell 1. Examples for exploration should include regulation of 2005 as a living system temperature, pH, blood glucose levels and water balance. Edition including: 2. Discussion should include active vs. passive transport, Maintenance of diffusion, osmosis, and the porous nature of the semiCH 7, 171homeostasis. permeable plasma membrane. (Pinocytosis, phagocytosis, 187 Movement of endocytosis, and exocytosis have been deliberately CH 8, 8.1, materials into and excluded) 195-200 out of cells. 3. Given different types of cells, students should be able CH 9, 9.1, Energy use and to predict any changes in osmotic pressure that may 221-224 release in occur as the cell is placed in solutions of differing biochemical concentrations. (Emphasis is on the processes, not reactions. terminology such as hypertonic, isotonic, hypotonic, turgor pressure) 4. Examine ATP as the source of energy for cell activities. 5. Students will describe how cells store and use energy with ATP and ADP molecules Instruction SHOULD include: 2.02 Investigate and describe the structure and function of cells including: Cell organelles Cell specialization. Communication among cells Goal Vocabulary Course Objective 4 4 Biology Curriculum 4.01 Analyze the Instruction SHOULD include: classification of organisms History of classification system according to their Originally two kingdoms (plants and animals). More evolutionary kingdoms added as knowledge of the diversity of organisms relationships. increased. The historical Development of the seven level classification system development and (KPCOFGS) and binomial nomenclature changing nature of Basis of classification system classification Evolutionary phylogeny, DNA and biochemical analysis, systems. embryology, morphology Similarities and Interpret phylogenetic trees. differences between Only basic differences and similarities should be detailed. eukaryotic and Membrane bound organelles – none in prokaryotes. prokaryotic Ribosomes in both. organisms. Contrasts in chromosome structure. Similarities and Contrasts in size. differences among Compare: the eukaryotic Cellular structures. kingdoms: Protists, Unicellular vs. Multicellular. Fungi, Plants, and Methods of making/getting food and breaking down food to Animals. get energy. Classify organisms Reproduction. using keys Use dichotomous keys to identify organisms. Representati 4.02 Analyze the Instruction SHOULD include the comparison and contrast ve processes by which how the organisms listed accomplish the essential life Organisms organisms functions specified below. The focus is on physiology rather representative of the than on the names of parts. following groups accomplish essential Transport – how organisms get what they need to cells; how life functions they move waste from cells to organs of excretion. including: Excretion – how organisms get rid of their waste and balance their fluids (pH, salt concentration, water). Groups: Regulation – how organisms control body processes – Unicellular protists, hormones, nervous system. annelid worms, Respiration – how organisms get oxygen from the insects, amphibians, environment and release carbon dioxide back to the mammals, nonenvironment and how plants exchange gases. vascular plants, Nutrition – how organisms break down and absorb foods. gymnosperms and Synthesis – how organisms build necessary molecules. angiosperms. Reproduction – sexual versus asexual, eggs, seeds, spores, placental, types of fertilization. Essential Life Growth and development – metamorphosis, development in Functions egg or in uterus, growth from seed or spore. Transport, excretion, respiration, regulation, nutrition, synthesis, reproduction, and Related Chapters 2000 Edition CH 17, 453-473 2005 Edition CH 17, 443-459 2000 Edition (Pgs) 519-525 597-607 608-617 661-666 748-753 771- 774 827-833 867-873 2005 Edition (Pgs) 503-509 577-587 588-597 641-645 728-733 747-755 803-809 841-847 4.05 Analyze 4 Animal Behavior the Instruction SHOULD include: broad patterns of animal behaviors as Taxes and instincts, including: adaptations to the • suckling (instinct) environment: • insects moving away from or toward light (taxis) • migration, estivation, hibernation Innate behavior Learned Behavior Focus should be on various types of learned behavior including: • Habituation Social behavior • Imprinting • Classical conditioning (e.g. Pavlov’s dog –stimulus association) • Trial and error (focus on concept of trial and error learning not term operant conditioning). Focus should be on communication, territorial defense, and courtship, including: • Communication within social structure using pheromones (ex: bees and ants). • Courtship dances. • Territorial defense (ex: Fighting Fish). 2005 Edition 216 312-313 323-324 508-509 928 10231041 Goal 5 5 5 Vocabulary Course Objective Words Symbiosis Mutualism 5.01 Investigate and analyze Commensalism the interrelationships among Parasitism organisms, populations, Abiotic/Biotic communities and ecosystems Niche Techniques of field ecology Habitat Abiotic and biotic factors Population Carrying capacity Community Ecosystem Succession (Primary and Secondary) Limiting Factor Climax Community Predator Prey Lichen Species Organism Carrying Capacity Exponential Growth Heterotroph Scavenger Trophic Level Food Web/Chain Autotroph Ominvore Carnivore Herbivore Decomposers Natural Resources Nonrenewable Resources Renewable Resources Extinction Threatened Species Endangered Species Biodiversity 5.02 Analyze the flow of energy and the cycling of matter in the ecosystem. Relationship of the carbon cycle to photosynthesis and respiration Trophic levels- direction and efficiency of energy transfer Biology Curriculum Related Chapters Instruction SHOULD include: Identification and description of symbiotic relationships Mutualism Commensalism Parasitism Students should be able to identify and predict patterns in Predator /prey relationships. Use field ecology techniques such as sampling and quadrant studies to determine species diversity and changes over time. Explain how abiotic and biotic factors are related to one another and their importance in ecosystems. Analyze how limiting factors influence carrying capacity (e.g. food availability, competition, harsh winter). Interpret population growth graphs. 2005 Edition CH 2, 2.1, 3545 CH 4, 4.1, 9199 Instruction SHOULD include: Investigate the carbon cycle as it relates to photosynthesis and respiration. Analyze food chains, food webs and energy. 5.03 Assess human population Instruction SHOULD include: and its impact on local ecosystems and global Analyze human population growth graphs environments: (historical and potential changes) .(See 5.01) Factors influencing birth rates and death rates. Historic and potential changes Effects of population size, density and resource in population use on the environment. Factors associated with those Discussion of human impact on local changes. ecosystems: Climate Change. Acid rain Resource use Habitat destruction Sustainable practices/ Introduced non-native species. 2005 Edition CH 2, 2.2, 4657 2005 Edition CH 4, 4.1, 9199 CH 4, 4.2 100103 CH 5, 111-125