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Download Oncogene Tumor suppressor gene dominant gain-of-function mutations promote cell transformation
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Oncogene — dominant gain-of-function mutations promote cell transformation Tumor suppressor gene — recessive, loss-of-function mutations promote cell transformation Images removed due to copyright reasons. Daughter cells Extracellular growth control signals G0 Intracellular quality control checks M (Mitosis) G1 G2 S (DNA synthesis) Figure by MIT OCW. Cell cycle in S. cerevisiae Mother cell Cytokinesis Daughter cell Chromosome segregation; nuclear division Growth G1 M START Spindle pole body duplication Spindle formation S G2 Bud emergence DNA replication Nuclear migration Figure by MIT OCW. A Genetic Screen for Cell Cycle Mutants Figure by MIT OCW.
