* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Presentation
Polycomb Group Proteins and Cancer wikipedia , lookup
Cre-Lox recombination wikipedia , lookup
Behavioural genetics wikipedia , lookup
Nucleic acid analogue wikipedia , lookup
Genetically modified crops wikipedia , lookup
Primary transcript wikipedia , lookup
Epigenetics of diabetes Type 2 wikipedia , lookup
Medical genetics wikipedia , lookup
Minimal genome wikipedia , lookup
Genome evolution wikipedia , lookup
Non-coding DNA wikipedia , lookup
Transgenerational epigenetic inheritance wikipedia , lookup
Point mutation wikipedia , lookup
Site-specific recombinase technology wikipedia , lookup
Extrachromosomal DNA wikipedia , lookup
Deoxyribozyme wikipedia , lookup
Genetic engineering wikipedia , lookup
Biology and consumer behaviour wikipedia , lookup
Gene expression profiling wikipedia , lookup
Cell-free fetal DNA wikipedia , lookup
Genomic imprinting wikipedia , lookup
Genome (book) wikipedia , lookup
Vectors in gene therapy wikipedia , lookup
Nutriepigenomics wikipedia , lookup
Therapeutic gene modulation wikipedia , lookup
Helitron (biology) wikipedia , lookup
Hardy–Weinberg principle wikipedia , lookup
Epigenetics of human development wikipedia , lookup
X-inactivation wikipedia , lookup
Artificial gene synthesis wikipedia , lookup
History of genetic engineering wikipedia , lookup
Quantitative trait locus wikipedia , lookup
Designer baby wikipedia , lookup
S7L3. Students will recognize how biological traits are passed on to successive generations. A.Explain the role of genes and chromosomes in the process of inheriting a specific trait. B. Compare and contrast that organisms reproduce asexually and sexually (bacteria, protists, fungi, plants, and animals). C. Recognize that selective breeding can produce plants or animals with desired traits. DNA • DNA is often called the blueprint of life. • In simple terms, DNA contains the instructions for making proteins within the cell. Why do we study DNA? We study DNA for many reasons: • its central importance to all life on Earth • medical benefits such as cures for diseases • better food crops. Chromosomes and DNA • Chromosomes are made up of genes. • Genes are made up of a chemical called DNA. The Nucleus • DNA is located in the nucleus The Shape of the Molecule • DNA is a very long molecule. • The basic shape is like a twisted ladder or zipper. • This is called a double helix. Nucleotides One deoxyribose together with its phosphate and nitrogen base make a nucleotide. O O -P O O Phosphate Nitrogen base O C C C O Deoxyribose One Strand of DNA • The backbone of the molecule is alternating phosphate and deoxyribose sugar parts. • The steps are nitrogen bases. phosphate deoxyribose bases Four nitrogenous bases DNA has four different bases: • • • • Cytosine Thymine Adenine Guanine C T A G Important Adenine and Thymine always join together A -- T Cytosine and Guanine always join together C -- G Two Stranded DNA • Remember, DNA has two strands that fit together something like a zipper. • The teeth are the nitrogen bases but why do they bond together? Hydrogen Bonds • When making hydrogen bonds, cytosine always pairs up with guanine, • And adenine always pairs up with thymine. • (Adenine and thymine are shown here.) O N O C C C C N C Do Now! • Where is DNA located? • What does it look like? • What are its bases? • Why do you think DNA is located there? DNA Synthesis/DNA Replication • Step 1- DNA unwinds and unzips • Step 2- Once the molecule is separated it copies itself. • The new strand of DNA has bases identical to the original What are the main differences between DNA and RNA 1. Thymine is replaced by the nitrogen base Uracil. 2. Deoxyribose sugar is replaced by Ribose sugar. 3. DNA is double stranded, while RNA is a single strand. RNA • In RNA Thymine is replaced by Uracil • A-U (RNA) • not • A-T (DNA) • IF the DNA strand is GTACCAGATTAGC • What would the matching RNA strand be? G TAC CAGATTAG C C A U G G U C U AA U C G Protein Synthesis Codon • The flow of information from gene to protein is based on codons. • A codon is a threebase word that codes for one amino acid • The flow of information from gene to protein is based on codons. Information Flow: DNA to RNA to Protein Transcription • When a secretary transcribes a speech, the language remains the same. However, the form of the message changes from spoken to written Transcription • Transcription- RNA is made from a DNA template in the nucleus. • This type of RNA is called messenger RNA or mRNA Transcription • DNA is protected inside the nucleus. • mRNA carries the message of DNA into the cytoplasm to the ribosome's Translation • To translate English into Chinese requires an interpreter. • Some person must recognize the words of one language and covert them into the other. tRNA Transfer RNA • The cells interpreter • tRNA translated the three-letter codons of mRNA to the amino acids that make up protein. Translation • Genetic translation converts nucleic acid language into amino acid language. S7L3. Students will recognize how biological traits are passed on to successive generations. A.Explain the role of genes and chromosomes in the process of inheriting a specific trait. B. Compare and contrast that organisms reproduce asexually and sexually (bacteria, protists, fungi, plants, and animals). C. Recognize that selective breeding can produce plants or animals with desired traits. Genetics and Heredity History • Genetics is the study of genes. • Inheritance is how traits, or characteristics, are passed on from generation to generation. • Heredity is the passing of traits from parents to offspring. • Chromosomes are made up of genes, which are made up of DNA. • Genetic material (genes,chromosomes, DNA) is found inside the nucleus of a cell. • Gregor Mendel is considered “The Father of Genetics" Mendelian Genetics Vocabulary • • • • • • • • Dominant traits- traits that are expressed. Recessive traits- traits that are covered up. Alleles- the different forms of a characteristic. Probability- the chances/ percentages that something will occur. – Punnett Squares- show how crosses are made. Genotype- the types of genes (Alleles) present. Phenotype- what it looks like. Homozygous genotype- two of the same alleles. Heterozygous genotype- two different alleles. Gregor Mendel (1822-1884) • Austrian Monk. • Experimented with “pea plants”. • Used pea plants because: – They were available – They reproduced quickly – They showed obvious differences in the traits Understood that there was something that carried traits from one generation to the next“FACTORS”. Mendel's Plant Breeding Experiments Gregor Mendel was one of the first to apply an experimental approach to the question of inheritance. For seven years, Mendel bred pea plants and recorded inheritance patterns in the offspring. Mendel’s Terminology • True breeding (purebred): When the plants self-pollinate, all their offspring are of the same variety. • Hybridization: Mating, or crossing, of two varieties. • Inbreeding: The crossing of two individuals that have similar traits. • Monohybrid cross: A cross that tracks the inheritance of a single characteristic. • P generation: True breeding parents. • F1 generation: (first filial) Hybrid offspring of the P generation. • F2 generation: (second filial) Offspring from the selffertilization of the F1 hybrids. Mendel’s law of Dominance • In a cross of parents that are pure for contrasting traits, only one form of the trait will appear in the next generation. Offspring that are hybrid for a trait will all have only the dominant trait in the phenotype. Mendel’s law of segregation • During the formation of gametes (ovum or sperm), the two alleles responsible for a trait separate from each other. Alleles for a trait are then “recombined” at fertilization, producing the genotype for the trait of the offspring. • Mendel discovered this 1860. • DNA was not discovered until 1953. Mendel’s law of Independent Assortment • Alleles for different traits are distributed to gametes independently of one another. Reproduction in Flowering Plants Review •Pollen contains sperm –Produced by the stamen •Ovary contains eggs –Found inside the flower Pollen carries sperm to the eggs for fertilization Self-fertilization can occur in the same flower Cross-fertilization can occur between flowers Mendel’s Experimental Methods •Mendel hand-pollinated flowers using a paintbrush –He could snip the stamens to prevent self-pollination –Covered each flower with a cloth bag •He traced traits through the several generations Mendel was fortunate he chose the Garden Pea •Mendel probably chose to work with peas because they are available in many varieties. •The use of peas also gave Mendel strict control over which plants mated. •Fortunately, the pea traits are distinct and were clearly contrasting. To test the hypothesis, Mendel crossed true-breeding plants that had two distinct and contrasting traits—for example, purple or white flowers. What is meant by “true breeding?” Mendel cross-fertilized his plants by hand. Why is it important to control which plants would serve as the parents? For each monohybrid cross, Mendel cross-fertilized true-breeding plants that were different in just one character—in this case, flower color. He then allowed the hybrids (the F1 generation) to self-fertilize. Following the Generations P (Purebred Parents) TT x tt F1 Results = all Hybrids Tt F2 results = 3 Tall & 1 Short TT, Tt, tt Trait: Plant Height Paternal Gametes Sperm Maternal Gametes Egg Egg Sperm T T t Tt Tt t Tt Tt Probability and Punnett Squares Punnett square: diagram showing the probabilities of the possible outcomes of a genetic cross 1. What are the parent’s genotypes? 2. From this monohybrid cross, what is the probability of the parents producing a homozygous recessive offspring? 3. What is the probability of the parents producing a tall offspring ? Genotype versus phenotype. How does a genotype ratio differ from the phenotype ratio? Seven Pea Plant Traits • Seed shape --- Round (R) or Wrinkled (r) • Seed Color ---- Yellow (Y) or Green (y) • • • • Pod Shape --- Smooth (S) or wrinkled (s) Pod Color --- Green (G) or Yellow (g) Flower position---Axial (A) or Terminal (a) Plant Height --- Tall (T) or Short (t) • Flower color --- Purple (P) or white (p) Mendel studies seven characteristics in the garden pea Identify the correct vocabulary term for each condition presented These are the units which make up chromosomes. Responsible for inheritance of specific characteristics Eye color, skin color and hair color: They are controlled by genes. Sperm and egg cells are both this type of cell. Contain half the amount of DNA of normal diploid cells. When a sperm and egg cell fuse together, they produce this. We use this word to describe cells which contain the full complement of genetic material. In humans this would be 46 chromosomes (23 pairs) The different versions of genes Alleles of a given gene are identical (can be either dominant or recessive Alleles of a given gene are not identical Plants and animals with useful or desired traits are bred together to produce offspring with those desired traits The altering of the characteristics of an organism by inserting genes from another organism Division of the nucleus to produce 2 daughter nuclei which each has the same number and kind of chromosomes as the mother cell Type of reproduction that involves fusion of gametes S7L3. Students will recognize how biological traits are passed on to successive generations. A.Explain the role of genes and chromosomes in the process of inheriting a specific trait. B. Compare and contrast that organisms reproduce asexually and sexually (bacteria, protists, fungi, plants, and animals). C. Recognize that selective breeding can produce plants or animals with desired traits. A concept that can be used to predict the results of a particular event – Examples • Chance of a specific team winning a sporting event • Chance of a coin landing on heads in a coin toss – Predicts what is likely to occur, not necessarily what will actually occur Probability and Heredity • Think back to Mendel’s plant experiments – He noticed that traits were inherited in patterns • For example, when he crossed two plants that were heterozygous for stem height (Tt) he noticed their offspring would inherit this trait in a predictable pattern, with 3 out of 4 having tall stem height. Probability and Heredity • Each time Mendel repeated the cross, he would obtain similar results • He could say that the probability, or chance, of the cross producing a tall plant was 3 in 4 and the probability of producing a short plant was 1 in 4. Mendel noticed the same pattern of inheritance in other traits as well Probability and Punnett Squares • Punnett Square – A chart that shows how parents’ alleles might combine in an offspring – a tool that can help you understand the patterns of heredity – Geneticists use Punnett Squares to show all the possible outcomes of a genetic cross and to determine the probability of a particular outcome – Punnett Squares Explained at http://www.siskiyous.edu/class/bio1/genetics/monohybri d_v2.html Probability and Punnett Squares • What is the probabilty of….. – The offspring having a yellow seed color? 2 in 4 – The offspring having a green seed color? 2 in 4 Probability and Punnett Squares • How else can probability be written? – The offspring having a yellow seed color? 2 in 4 or 50% – The offspring having a green seed color? 2 in 4 or 50% Using a Punnett Square • In rabbits, black fur color is dominant to white. What is the probability of producing a white rabbit if two heterozygous rabbits mate? Using a Punnett Square • Step 1: figure out the genotype of the parents. • Black is dominant to white. – B - black – b - white • Parents are heterozygous. – Bb - dad – Bb - mom Using a Punnett Square • Step 2: set up a Punnett Square. B B b b Bb Bb Using a Punnett Square • Step 3: Fill in the Punnett Square. B B b b Using a Punnett Square • Step 3: Fill in the Punnett Square. B B b BB b Using a Punnett Square • Step 3: Fill in the Punnett Square. B B b BB b Bb Using a Punnett Square • Step 3: Fill in the Punnett Square. B B BB b Bb b Bb Using a Punnett Square • Step 3: Fill in the Punnett Square. B b B BB Bb b Bb bb Using a Punnett Square • Step 4: Count the results. B b B BB Bb b Bb bb • Genotypes – 1 homozygous dominant Using a Punnett Square • Step 4: Count the results. B b B BB Bb b Bb bb • Genotypes – 1 homozygous dominant – 2 heterozygotes Using Punnett Square • Step 4: Count the results. B b B BB Bb b Bb bb • Genotypes – 1 homozygous dominant – 2 heterozygotes – 1 homozygous recessive Using a Punnett Square • Step 4: Count the results. B b B BB Bb b Bb bb • Genotypes – 1 homozygous dominant – 2 heterozygotes – 1 homozygous recessive • Phenotypes Using a Punnett Square • Step 4: Count the results. B b B BB Bb b Bb bb • Genotypes – 1 homozygous dominant – 2 heterozygotes – 1 homozygous recessive • Phenotypes – 3 black fur Using a Punnett Square • Step 4: Count the results. B b B BB Bb b Bb bb • Genotypes – 1 homozygous dominant – 2 heterozygotes – 1 homozygous recessive • Phenotypes – 3 black fur – 1 white fur Probability and Punnett Squares • In rabbits, black fur color is dominant to white. What is the probability of producing a white rabbit if two heterozygous rabbits mate? – 1 in 4 or 25% Representing Ratios • Probability can also be represented in ratios – A ratio compares or shows the relationship between a part to the whole • Example the probability that a coin will land on heads in a single coin toss is 1 in 2 or 50% – As a ratio, the probability would be written as 1:2 and would be read as, “One to two.” – In genetics we use ratios to represent probability Using a Punnett Square • Step 4: Count the results. B b B BB Bb b Bb bb • Genotypes = – – – – 1 homozygous dominant 2 heterozygotes 1 homozygous recessive Genotypic Ratio = 1:2:1 • Phenotypes – 3 black fur – 1 white fur Using a Punnett Square • Step 4: Count the results. B b B BB Bb b Bb bb • Genotypes = – – – – 1 homozygous dominant 2 heterozygotes 1 homozygous recessive Genotypic Ratio = 1:2:1 • Phenotypes – 3 black fur – 1 white fur – Phenotypic Ratio = 3:1 Let’s Practice 1. In pine trees, long needles are dominant over short needles. Cross a homozygous dominant plant with a plant that is heterozygous. What is the probability that the parents will produce offspring that have short needles? Give the genotypic and phenotypic ratios. Let’s Practice 2. In cats, a striped coat is dominant over a solid coat. Cross a cat with a solid coat with a cat that is heterozygous for a striped coat. What is the probability that the parents will produce offspring with a solid coat? Give the genotypic and phenotypic ratios. What does pedigree mean? Pedigree: a diagram that traces one trait through several generations of a family = female = male Example #1 3 How many girls? ___ 2 How many boys? ___ mom daughter #1 dad daughter #2 son mom dad oldest daughter #1 youngest daughter #2 son A horizontal line connecting two shapes represents a cross/marriage. mom dad Example #2 How many crosses/marriages? 2 A C B D E F G A vertical line extending down from a marriage/cross represents that the couple has children. mom dad A C B D questions… E F G Example #3 A C How many couples have children? B D H G E F M J N P K L O Q ? R S T 4 How do you show twins? A C B D E F How do you show traits? Shading ( shaded = recessive ) RR Rr rr Mutation/ Deceased **A pedigree chart follows one trait. Rr mom RR dad R = tongue roller r = non-roller Rr son Rr daughter RR daughter R R R RR RR r Rr Rr A C B D H H G E F M J N P K L O Q R S T Interpreting a Pedigree • What can you tell from a pedigree? – Whether a family has an autosomal or sex-linked disease or disorder • Autosomal disorder: appears in both sexes equally • Sex-linked (X-linked)disorder: allele is located only on the X or Y chromosome. Most sex-linked genes are on the X chromosome and are recessive • So who would have an X-linked disorder more often, boys or girls? – Whether a disorder is dominant or recessive Sex determination Sex chromosomes – determines the sex of an individual Y X Males have X and Y Two kinds of gametes Female have two X’s Only one type of gamete Which parents determines the sex of the offspring? XY male X XX Y X Female X It is the male that determines the sex of the offspring. Sex Linked Traits Traits controlled by genes located on sex chromosomes (X or Y) Most are X-linked The X chromosome is larger and has more genes Y has very few genes Show inheritance patterns that differs for autosomal traits. X-linked Inheritance Males only have one copy of the X chromosome (hemizygous), plus a Y Female have two X chromosomes, and may be homozygous or heterozygous for a trait X-linked genes are never passed from father to son. The Y chromosome is the only sex chromosome that passes from father to son. Females with one copy of the normal gene and one copy of the mutated gene are called carriers. They don’t show the trait. Males are never carriers – if they have a mutated gene on the X chromosome, it will be expressed X-linked disorders Recessive Red-green color blindness Hemophilia Dominant Hypertrichosis Red-green color blindness Can not distinguish red from green. Normal redgreen Red-green colorblind Sickle Cell Anemia Disorder where abnormal hemoglobin (a protein inside red blood cells) is produced and warps red blood cells Sickle cells deliver less oxygen to body’s tissues and can get stuck in small blood vessels Autosomal Recessive trait, tends to be seen in people of African or Mediterranean descent Cystic Fibrosis Recessive, autosomal disease Life threatening, causes thick mucus to build up in various areas of the body (lungs, digestive tract, etc). Tends to run in Caucasians, of Northern/Central European descent (1 in 29 Americans carry the allele) Average life span in US for people with CF is 37, death usually caused by lung complications Hemophilia Bleeding disorder, where it takes a long time for blood to clot (body lacks proteins involved in clotting) Recessive, Sex-linked (carried on the X chromosome) Treatment involves injection with missing clotting protein Make a cross with an X-linked gene Hemophilia is an X-linked ________________ recessive ________________ disease H for normal dominant blood Use ______ clotting gene. h for recessive hemophilia gene. Use ______ h X On X chromosome so write it as ________ Mother H H Without hemophilia = X X H Without hemophilia = X X h With hemophilia = X X h h Unaffected Carrier Affected Father H Without hemophilia = X Y h With hemophilia = X Y Unaffected Affected Make a cross with an X-linked gene H X H X h X Y H H X X H h X X H X Y h X Y Carrier Mom X Normal dad GIRLS 50% = normal _______ 50% = look normal _______ but are CARRIERS BOYS 50% = normal _______ _______ 50% = hemophilia Hemophilia Incomplete Dominance Codominance Multiple Alleles In a nutshell! Dominant/Recessive • One allele is dominant over the other (capable of masking the recessive allele) PP = purple pp = white Pp = purple Dominant/Recessive • In pea plants, purple flowers (P) are dominant over white flowers (p) show the cross between two heterozygous plants. GENOTYPES: - PP (1); Pp (2); pp (1) - ratio 1:2:1 PHENOTYPES: - purple (3); white (1) - ratio 3:1 P p P PP Pp p Pp pp Incomplete Dominance • A third (new) phenotype appears in the heterozygous condition. • Flower Color in 4 O’clocks RR = red rr = white Rr = Pink Incomplete Dominance • In Incomplete Dominance, every genotype has its own phenotype. (One allele not completely dominant over the other.) Third phenotype that is a blending of the parental traits. (2 alleles produce 3 phenotypes.) – Result: Heterozygous phenotype somewhere in between homozygous phenotype. Problem: Incomplete Dominance • Show the cross between a pink and a white flower. GENOTYPES: - Rr (2); rr (2) - ratio 1:1 PHENOTYPES: - pink (2); white (2) - ratio 1:1 R r r Rr rr r Rr rr Codominance In codominance, neither alleles are dominant; both are expressed. A cross between organisms with two different phenotypes produces offspring with has both phenotypes of the parental traits shown. Codominance • Both alleles contribute to the phenotype. – Example: In some chickens Black Chicken x White Speckled Chicken YOU tell me which type of dominance… Codominance! Type of Dominance? Incomplete Dominance! Type of Dominance? Incomplete Dominance! Multiple Alleles • There are more than two alleles for a trait • Example: Blood type in humans • Blood Types? (phenotypes) – Type A, Type B, Type AB, Type O • Three Blood Alleles – A, B, O ( IA, IB, i) Rules for Blood Type (Genotypes) • A and B are codominant – AA = Type A – BB = Type B – AB = Type AB • A and B are dominant over O – AO = type A – BO = type B – OO = type O • The alleles are as follows: ALLELE IA IB i CODES FOR Type "A" Blood Type "B" Blood Type "O" Blood • According to the symbols used in the table below, that the allele for "O" (i) is recessive to the alleles for "A" & "B". • With three alleles we have a higher number of possible combinations in creating a genotype. GENOTYPES RESULTING PHENOTYPES IAI A Type A IAi Type A IBIB Type B IBi Type B I AI B Type AB ii Type O Problem: Multiple Alleles • Show the cross between a mother who has type O blood and a father who has type AB blood. O O GENOTYPES: - AO (2) BO (2) - ratio 1:1 A AO AO PHENOTYPES: - type A (2); type B (2) - ratio 1:1 B BO BO Problem: Multiple Alleles • Show the cross between a mother who is heterozygous for type B blood and a father who is heterozygous for type A blood. GENOTYPES: -AB (1); BO (1); AO (1); OO (1) - ratio 1:1:1:1 PHENOTYPES: -type AB (1); type B (1) type A (1); type O (1) - ratio 1:1:1:1 A O B AB BO O AO OO Sample Problem A woman with Type O blood and a man who is Type AB are expecting a child. What are the possible blood types of the kid? Solve this using the symbols for blood type alleles & the good old punnett square. 1. Figure out the genotypes of mom & dad using the given info. 2. "Woman with Type O" must be ii, because that is the one & only genotype for Type O. 3. "Man who is AB" must be IAIB, again because it is the one & only genotype for AB blood. 4. So our cross is: ii x IAIB. Make a punnett square As you can see, our results are as follows: 50% of kids will be heterozygous with blood Type A 50% will be heterozygous with blood Type B Multiple Alleles vs. Polygenic • Polygenic = is the inheritance pattern of a trait that is controlled by two or more genes. Each gene may have two or more alleles • The resulting phenotype usually shows a range of value for the trait. (ie. human height or human hair color) Genetics IF: Prince Charming is blond What color hair should their children have? Snow White has dark hair First you must understand: There are three basic kinds of genes: – Dominant - A gene that is always expressed and hides others – Recessive - A gene that is only expressed when a dominant gene isn’t present – Codominant - Genes that work together to produce a third trait Genetics Dominant and Recessive Genes • A dominant gene will always mask a recessive gene. • A “widows peak” is dominant, not having a widows peak is recessive. • If one parent contributes a gene for a widows peak, and the other parent doesn’t, the offspring will have a widows peak. Widows Peak Genetics Punnet Square - A tool we use for predicting the traits of an offspring – Letters are used as symbols to designate genes – Capital letters are used for dominant genes – Lower case letters are used for recessive genes – Genes always exist in pairs Genetics A Widows Peak, dominant, would be symbolized with a capital “W”, while no widows peak, recessive, would be symbolized with a lower case “w”. Father - No Widows Peak - w Mother - Has a Widows Peak - W Genetics All organisms have two copies of each gene, one contributed by the father, the other contributed by the mother. Homozygous - Two copies of the same gene Heterozygous - Two different genes Genetics For the widows peak: WW - has a widows peak Ww - has a widows peak ww - no widows peak Homozygous dominant Heterozygous Homozygous recessive Genetics Since Herman has no widows peak, he must be “ww”, since Lilly has a widows peak she could be either “WW” or “Ww” ww Either Ww or WW Homozygous recessive Heterozygous Homozygous dominant Genetics We can use a “Punnet Square” to determine what pairs of genes Lilly has • A Punnet Square begins with a box 2 x 2 Assume Lilly is heterozygous Ww Assume Herman is homoozygous recessive ww • One gene is called an “allele” W w w Ww ww w Ww ww • One parents pair is split into alleles on top, the other along the side • Each allele is crossed with the other allele to predict the traits of the offspring Genetics Notice that when Lilly is crossed with Herman, we would predict that half the offspring would be “Ww”, the other half would be “ww” Half “Ww”, Heterozygous, and will have a widows peak Half “ww”, Homozygous, and not have a widows peak W w w Ww will ww w Ww ww Genetics Another possibility is that Lilly might be “WW”, homozygous dominant. Assume Lilly is homozygous dominant WW W Assume Herman is homoozygous ww W w Ww Ww w Ww Ww Notice that all the offspring are heterozygous and will have a widows peak Genetics So which is true? Is Lilly homozygous dominant (WW) or is she heterozygous (Ww)? W w W W w Ww ww w Ww Ww w Ww ww w Ww Ww Genetics If Lilly were heterozygous, then 1/2 of their offspring should have a widows peak, 1/2 shouldn’t W If Lilly were homozygous, all of their children will have a widows peak w W W w Ww ww w Ww Ww w Ww ww w Ww Ww Genetics Recall that Herman and Lilly had another offspring, Marylin. She had no widows peak, therefore, Lilly must be heterozygous. Genetics So, back to the original question. What color hair will the offspring of Prince Charming and Snow White have? Genetics Hair color is different from widows peak, no color is truly dominant. – Brown and blond are the two, true traits – Homozygous conditions produce either brown or blond hair – Heterozygous conditions produce red hair Genetics For Snow White to have brown hair she must be homozygous dominant, “BB”, a blond Prince Charmin must be homozygous recessive, “bb”. B B b Bb Bb b Bb Bb Genetics All the offspring from Prince Charming and Snow White will therefore be heterozygous, “Bb”, and since hair color is codominant….. all their children will have red hair. + Are you the Dominant or Recessive type? Dominant: overpowers the recessive; will be expressed if one or both genes in the genotype is/are dominant Recessive: is masked by the dominant; will only be expressed if both genes in the genotype are recessive Tongue Rolling Recessive = non-roller Dominant = roller RR or Rr rr Ear Lobes Dominant = free Recessive = attached EE or Ee ee Hairline Dominant = widow’s peak Recessive = straight AA or Aa aa Hair Color Dominant = Non-red Recessive = Red DD or Dd dd Dimples Dominant = Dimples Recessive = no dimples II or Ii ii Hair Dominant = Curly/wavy Recessive = straight NN or Nn nn Eyelashes Dominant = Long Recessive = Short GG or Gg gg