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Mendelian Genetic • SC.912.L.16.1 – Analyze pattern of inheritance using Mendel’s Law of segregation and independent assortment • SC.912.L.16.2 – Identify, analyze, and/or predict traits caused by various modes of inheritance, including: • Dominant, incomplete dominance, recessive, co-dominant, sexlinked, polygenic, multiple alleles – Predict the genotype and phenotype of the P1 and F1 generations using Punnett squares and pedigree diagrams – Construct a dihybrid cross that results in the ratio of 9:3:3:1 https://www.youtube.com/watch?v=Mehz7tCxjSE How do the laws of segregation and independent assortment affect the analysis of inheritance patterns? • Traits are inherited independently of one another. – Ex: Just because you have blonde hair does not mean you will have blue eyes. Dominant vs Recessive • Dominant allele is allele that is expressed when two different alleles or two dominant alleles are present (upper case letter= A) • Recessive allele is allele that is only expressed when two copies are present (lower case letter=a) How does the mode of inheritance (dominance, codominance, etc.) affect the prediction and analysis of inheritance patterns? RrYy Phenotypic Ratio= 9:3:3:1 Biotechnology SC.912.L.16.10 • evaluate the possible impact of biotechnology on the individual, society, and the environment, including medical and ethical issues, such as: – – – – – karyotyping DNA fingerprinting cloning gene therapy genetically modified foods and artificial selection • analyze how heredity and family history can impact personal health Karyotype -describes the number of chromosomes and what they look like under a microscope -can be used to study chromosomal abnormalities, disorders, evolutionary relationships among species, etc… DNA Fingerprinting -procedure where the genetic information in a person's cells is analyzed and identified -no two person's genetic code is exactly the same which makes DNA fingerprinting a very useful tool for our modern society. It can be used to: Determine Family Relationship Detect Inherited Diseases Prove Guilt or Innocence Identify a Dead Body Gene Therapy -experimental technique that uses genes to treat or prevent disease Recombinant DNA -DNA made from 2 or more different organisms Genetically Modified Foods -creating “herbicide resistant” crops (kill weeds, not crops) -drought resistant crops -“healthier” food infused with vitamins Pedigrees Analysis https://www.youtube.com/watch?v=Wuk0W10EveU Do you really understand this? Mendel hypothesized that reproductive cells have only one factor for each inherited trait. This hypothesis is supported by which observation? A. Haploid cells are produced by mitosis. B. Diploid cells are produced by mitosis. C. Haploid cells are produced by meiosis. D. Diploid cells are produced by meiosis. A human baby boy inherits a recessive allele from his mother. In which circumstance would he most likely show the trait coded for by the recessive allele? A. The baby inherits the dominant allele from his father. B. The allele is on an autosomal chromosome and the baby is a twin. C. The allele is on the X chromosome. D. The allele is on the Y chromosome. This diagram shows a diploid cell with two pairs of homologous chromosomes. Due to independent assortment, what is the possible genetic make-up of gametes produced by this organism? A. SsTt B. Ss, Tt C. S, s, T, t D. ST, St, sT, st This diagram shows a pedigree for a recessive genetic disorder. What is the genotype of individual 6? A. XHXH B. XHXh C. XHY D. XhY The way that crimes are solved today was affected by which of the following technologies? A. gene therapy B. DNA fingerprinting C. genetic testing D. Genetic modification