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Transcript
2010 Pilot
Sample Outcomes & Items
Organic Chemistry
Amides are organic compounds which can be
found in plants (coffee, tea, etc.) and in some
medicinal drugs (paracetamol, penicillin, etc.).
Outcome:
To realize that an amide: (a) is an acid derivative
where the hydroxyl group -OH is substituted by the
amino group -NR2, and that (b) it can be obtained
from the reaction between a carboxylic acid and an
amine.
Question 1:
The organic synthesis of an amide requires 2
compounds. What families of organic molecules do
these 2 compounds belong to?
Outcome:
Analysis of the reactivity of a given amide in acidic
water reveals that amides hydrolyze to the parent
acid and the appropriate amine, whereas in
hydrolysis a molecule is cleaved into two parts by
the addition of a molecule of water.
Question 2:
Amides can be hydrolyzed under acidic or basic
conditions. Describe the reaction of hydrolysis and
give the obtained compounds in acidic medium.