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Objective: Learners will be able to complete a gallery walk activity in order to review for the Genetics Unit of the Biology HSA exam. Drill: 1. Take out the cards your teacher has given you. 2. Match up the vocabulary words with the definition and the picture that best represents each word. 3. Work with your neighbor to discuss answers and then copy the correct answers onto your “Genetics Vocabulary Chart.” Vocabulary Genotype Phenotype Homozygous Definition The alleles (letters) that represent a trait. TT or tt The external or physical appearance of a gene. black Both alleles (letters) for gene are same Alleles (letters) for the gene are different Heterozygous Picture Think-Pair-Share: work with your neighbor and complete questions #1-4 on your “Punnett Square Practice Problems” worksheet. Let’s review the answers as a class, then try some more Punnett squares. Let’s complete #5-7 on your “Punnett Square Practice Problems” worksheet. Parent 1 Genotype: b Bb Brown Fur Parent 1 Phenotype: B Parent 2 Genotype: b Bb Bb bb bb bb Parent 2 Phenotype: White Fur b Genotype ratio: 2 : 2 Phenotype ratio: 2 : 2 Roger has short ears. Genevieve is heterozygous for long ears. Use the steps below to solve the problem. Determine the parent’s genotype and phenotype PARENT #1: PARENT #2: E 1. What are the chances of a baby with the genotype Ee? out of or % e 2. What are the chances of a baby with short ears? out of or % e e Ee ee Ee ee Complete the notes on your “Chromosomes and Sex-Linked Traits” worksheet. If we take all the chromosomes out of one cell and match them up, we find that we have 23 pairs. The first 22 pairs contain the genes that make up our bodies (called autosomes). The 23rd pair are called sex chromosomes because they determine your gender. XX There are two different sex chromosomes, X and Y. If you receive an X and a Y, you are genetically a male. If you receive two X’s then you are genetically a female. XY X chromosomes can carry other traits besides those related to gender. Sex-Linked Traits Hemophilia Male Pattern Baldness Red-Green Colorblindness Duchenne Muscular Dystrophy Today we will look at hemophilia. In order to have offspring you need a female XX and a male XY. These crosses work just like the ones we have done in the past. XX= female baby XY= male baby Ratio = 2:2 or 50% Let’s cross a male with hemophilia with a carrier female. XH Xh Genotype Phenotype h H H X X X Normal h h XHXh XHXh X x XhXh Carrier hemophilia XHY Normal XhY hemophilia XHY Xh Y Y Since females have two X’s they need two alleles to get hemophilia. Because males only have one X, they only need one allele to get hemophilia. Antoinette has hemophilia but her husband Bobby is normal. •Draw a Punnett square to predict the genotypes of their children. Xh XH Xh XHxh XHxh XhY XhY •Determine how many children will have hemophilia. Y Mitosis starts with one parent cell. Each daughter cell also has 4 chromosomes. Parent cell starts with 4 chromosomes Afterwards you have two cells that are identical to the original cell. Growth Healing wounds Asexual Reproduction in Bacteria Cancer 4 Sperm 1 Egg Spermatogenesis Oogenesis 46 chromosomes Woman produces an egg. 23 chromosomes The male produces sperm. 23 chromosomes The sperm fertilizes the egg to make a zygote. Sperm and Egg only have 23 chromosomes and are created by a process called meiosis. Meiosis Mitosis Work with a partner to complete “Comparing and Contrasting Mitosis vs. Meiosis” worksheet. What information can we learn from this pedigree? Male Female 4 Generations Trait Inherited What kind of trait is inherited in this family? How do you know? Transcription Translation Scribes were people that used to copy books before the invention of the printing press. Transcription- is when DNA is copied into RNA DNA is our only copy of our genetic blueprint, so we need to keep it nice and safe in the nucleus. DNA has two strands DNA stays in nucleus DNA is larger RNA only has one strand RNA can go anywhere in the cell RNA is smaller RNA has A,U, G, C. DNA has A,T,G,C We can make a copy of a portion of our DNA, called RNA. We can then take RNA to our job site to build our proteins. This RNA is called mRNA because it has a message in it. We learned earlier that DNA has a code that provides instructions on how to build proteins. These instructions are passed on to the mRNA I’m a ribosome, I read the code in mRNA 3 letters at a time. The code in mRNA is read 3 letters at a time. Every 3 letters is called a codon, which codes for an amino acid. This step is called Translation. Codon = three letters = amino acid Third letter GTA CAU CAG GUC We can now translate the mRNA. Each codon equals an amino acid. We will get practice with pedigrees and protein synthesis during our gallery walk next! The artist captured man’s inner struggle with nature. Yeah whatever. It looks like a hot mess to me! You will work in groups of three to complete a gallery walk on Genetics Review problems. You will have a set time at each station. Let’ review answers as a class. Use your clickers to answer the old HSA questions. Don’t write on the handout!!! (Then turn in your clickers and your exit ticket paper) Your homework is to study for your Genetics VOCAB QUIZ!!!! Also keep working on your service learning project!!! Next class we will study for the evolution part of the HSA