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Cell Structure Chapter 5 Copyright © McGraw-Hill Companies Permission required for reproduction or display Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Cell Theory Schleidon and Schwann • All organisms are composed of one or more cells. Metabolism and heredity occur within these cells. • Cells are the basic units of organization for all organisms. • Cells arise only by division of a previously existing cell. Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Three Main Features of ALL Cells • • • • 1. Surrounded by a plasma membrane that encloses the cell and separates its contents from its surroundings - phospholipid bilayer with embedded proteins (transport proteins and receptor proteins) 2. Genetic material is enclosed within a nucleus or a nucleoid 3. Cytoplasm Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Cells Are Small • • The human body has approx. 100 Trillion Cells Cell diameter range: 7.5 micrometers (RBC) to 150 micrometers (ovum) Cells Are Small • Advantage of small cell size is explained by surface area-to-volume ratio. As a cell’s size increases, its volume increases much more rapidly than surface area. Cell membrane plays a key role in controlling cell function. - Small cells have more surface area per unit volume thus more effective communication. Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies • Prokaryotic Cells Bacterial cells are small, consisting of cytoplasm surrounded by a plasma membrane enclosed within a rigid cell wall of peptidoglycan (carbohydrate matrix crosslinked by short polypeptide units) Categorized by cell wall structure: - Gram Positive - Thick, single-layered cell wall. Gram Negative - Multilayered cell wall (less peptidoglycan) Many propelled by flagellum (flagella). Lack internal organization. Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Eukaryotic Cells • Interior of eukaryotic cells contain numerous membrane-bound structures (organelles) that close off compartments to allow multiple simultaneous biochemical processes. Vesicles - Storage and Transport (Plants and Animals) Nucleus – Chromosomes (DNA) Cytoskeleton - Internal Structure Central Vacuole - Storage (Plants Only) Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Nucleus Largest organelle: repository of genetic info. DNA is divided into chromosomes found in nucleus (chromatin) • Nucleolus in center: synthesizes rRNA • Nuclear envelope made of two phospholipid bilayers • Nuclear pores in envelope filled with proteins allow passage of two types of molecules • Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Endoplasmic Reticulum • • • Internal membrane composed of phospholipid bilayer and embedded proteins. Weaves through cell, creating series of cisternal channels between its folds (cisternae) Rough ER - Surface regions covered with ribosomes. Synthesizes proteins for export. Smooth ER - Membrane has few embedded ribosomes, and is embedded with enzymes for lipid synthesis, carbohydrate synthesis Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Golgi Apparatus • • Collection of interconnected flattened stacks of membranes (Golgi bodies). Each membrane is called a cisternae. Function in collection, packaging, and distribution of molecules synthesized in one place, and utilized in another place within the cell. - Cis face - Receiving end - Trans face - Discharging end Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Vesicles • • Lysosomes - Membrane-bound digestive vesicles that arise from Golgi apparatus. Contain degrading enzymes. - Break down old organelles and other structures and recycles them Microbodies - Bear enzymes for metabolism Glyoxysome - Convert fat into carbohydrates Peroxisome – Detoxify (those of kidneys and liver contain degrading enzyme catalase to detoxify hydrogen peroxide) metabolic waste, drugs, etc. Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Ribosomes • Ribosomes are site of protein synthesis. Made up of rRNA bound within complex of several dozen different proteins. Composed of two subunits (large RNA and smaller ribosomal protein) - Join to form functional ribosome only when they attach to messenger RNA. Assembled in nucleolus within the nucleus. Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Organelles With DNA • Mitochondria Bound by smooth outer membrane and an inner membrane folded into cristae. Contain own DNA. Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Copyright © McGraw-Hill Companies Permission required for reproduction or display Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Organelles With DNA • Chloroplasts Contain photosynthetic pigment chlorophyll that gives most plants their green color. Double membrane Grana - Stacked membranes internal to inner membrane. - Contain disk-shaped Thylakoids which also contain light-capturing pigments on surface Stroma – fluid surrounding grana Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Chloroplast Structure Copyright © McGraw-Hill Companies Permission required for reproduction or display Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Organelles With DNA • Centrioles - Barrel-shaped organelles usually located near nuclear membrane. Help assemble microtubules. Some appear to contain DNA. Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Cytoskeleton • Network of protein fibers supports cell shape. Individual fibers formed by polymerization. - Actin Filaments – cell movement and formation of cellular extensions - Microtubules – cell movement and moving material within cell - Intermediate Filaments – line organs and body cavities Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Cell Movement • • Some cells crawl via a pseudopod. Moving Material Within the Cell Short Distances – ER and Golgi Apparatus Long Distances - Molecular Motors - Vesicle - Microtubule Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Cell Movement • • Many eukaryotic cells contain flagellum consisting of a circle of nine microtubule pairs surrounding two central microtubules: “9+2 Structure” Flagella undulates with the help of flagella motor protein dynein. Cilia: short cellular projections often organized in rows that carry out a multitude of functions Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Plant Cells Central Vacuole - Functions as storage center and helps increase surface-to-volume ratio by stretching (swelling) cell • Cell Walls • Chloroplasts Plastids: organelle for photosynthesis and starch storage -Choroplasts -Leucoplasts -Amyloplasts • Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies Endosymbiosis • Theory of endosymbiosis proposes some eukaryotic organelles evolved by symbiosis. One species of prokaryote was engulfed and lived inside another. Raven - Johnson - Biology: 6th Ed. - All Rights Reserved - McGraw Hill Companies